Results 181 to 190 of about 5,279,387 (270)

FPGA‐Based Real‐Time Implementation of Closed‐Loop Brain‐Controlled Eye Movement System

CAAI Transactions on Intelligence Technology, Volume 11, Issue 5, Page 1626-1643, October 2026.
ABSTRACT This paper presents a comprehensive closed‐loop brain‐eye movement framework, spanning parametric modelling, dynamic analysis and real‐time FPGA implementation. A simplified first‐order oculomotor model was derived from the classical Robinson formulation to preserve the essential neural‐mechanical feedback structure while enabling efficient ...
Guodao Zhang, Yupeng Li, Yanjie Lu, Genfu Yang, Xiaotian Pan, Jing Wang   +5 more
wiley   +1 more source

Pregabalin Depresses Cerebellar Parallel Fiber-Purkinje Cell Synaptic Transmission by Modulating Glun2a-Containing Nmda Receptors in Mice In Vitro. [PDF]

Int J Mol Sci
Li MR, Zhang XD, Chen L, Zhang YD, Wang CY, Zhao ZY, Zhou M, Chu CP, Qiu DL.   +8 more
europepmc   +1 more source

Repeated Moderate and Severe Heat Exposure Has Divergent Effects on Skeletal Muscle Mitochondrial, Proteostatic and Neuromuscular Outcomes in Mice

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim Repeated heat exposure may promote adaptive remodeling or cumulative tissue burden depending on thermal dose, but its graded molecular and functional consequences during recovery remain unclear. We examined whether repeated moderate (39°C) and severe (41°C) whole‐body hyperthermia produce distinct skeletal muscle trajectories involving ...
Cansu Yakin, Cihan Suleyman Erdogan, Fatma Ozge Tuncel, Yunus Kosif, Bayram Yilmaz   +4 more
wiley   +1 more source

Depression of synaptic outputs by reduction of Ca²⁺ influx, but not RRP vesicles, becomes evident upon CB2R hyper-expression at cerebellar Purkinje cell terminals. [PDF]

Front Mol Neurosci
Inoshita T, Kawaguchi SY.
europepmc   +1 more source

Synaptic Proteostasis in Health and Disease

Journal of Neurochemistry, Volume 170, Issue 10, October 2026.
The localised creation and degradation of proteins at the pre and postsynaptic terminal are processes that are crucial for neuronal homeostasis. Synaptic proteostasis pathways are frequently reported as dysregulated in neurodevelopmental and neurodegenerative disorders.
Paul G. Donlin‐Asp, Emma L. Clayton
wiley   +1 more source

Cerebellar purkinje cell dysfunction contributes to gait impairments in Shank3-mutant mice. [PDF]

Mol Autism
Liu H, Huang X, Ma G, Zhao X, Xia R, Li Z, Guo B, Wu S, Wang W.   +8 more
europepmc   +1 more source

An eikonal model with re‐excitability for fast simulations in cardiac electrophysiology

The Journal of Physiology, Volume 604, Issue 19, Page 8264-8283, 1 October 2026.
Abstract figure legend Restitution properties obtained from cable‐equation simulations and anisotropic remeshing informed by local fibre orientation are combined in an eikonal model with re‐excitability. The resulting reduced electrophysiology model enables efficient simulations of recurrent activation patterns, here illustrated by atrial re‐entry ...
Lia Gander, Rolf Krause, Francisco Sahli Costabal, Simone Pezzuto   +3 more
wiley   +1 more source

Purkinje cell-specific loss of Neurofascin and Ankyrin G causes disruption of axon initial segments, neurodegeneration, and cerebellar ataxia. [PDF]

Front Cell Neurosci
Shi Q, Taylor AM, Sell LB, Bhat MA.
europepmc   +1 more source

Purkinje cell activity changes in cerebellar subregions during fear conditioning. [PDF]

Front Behav Neurosci
Pakusch J, Nair T, Grosch T, Mark MD.
europepmc   +1 more source

Cerebellar Purkinje cell firing reduction contributes to aging-related declining motor coordination in mice. [PDF]

Proc Natl Acad Sci U S A
Fields E, Rogers BC, Leung TCS, Huang A, Kern M, Kontowicz N, Dolin H, Watt AJ.   +7 more
europepmc   +1 more source