Results 181 to 190 of about 12,040,588 (301)

Cerebellar Purkinje cell firing reduction contributes to aging-related declining motor coordination in mice. [PDF]

Proc Natl Acad Sci U S A
Fields E, Rogers BC, Leung TCS, Huang A, Kern M, Kontowicz N, Dolin H, Watt AJ.   +7 more
europepmc   +1 more source

Long‐Acting Naltrexone Restores Network Connectivity in Subjects With Comorbid Cannabis and Opioid Use Disorder

Addiction Biology, Volume 31, Issue 5, May 2026.
This study describes functional connectivity (FC) in subjects with opioid use disorder (OUD‐only), OUD+CanUD (cannabis use disorder), OUD+AUD (alcohol use disorder), and OUD+CocUD (cocaine use disorder) before and after naltrexone (NTX). All groups displayed hyper connectivity at baseline; however, on‐NTX, OUD+CanUD and OUD+AUD showed a decrease in ...
Lindsey M. Brier, Daniel D. Langleben, Corinde E. Wiers, Zhenhao Shi   +3 more
wiley   +1 more source

Purkinje cell activity changes in cerebellar subregions during fear conditioning. [PDF]

Front Behav Neurosci
Pakusch J, Nair T, Grosch T, Mark MD.
europepmc   +1 more source

Alzheimer's disease and mixed pathologies as a hidden contributor to fatal hypothermia: A large‐scale forensic autopsy‐based study

Brain Pathology, Volume 36, Issue 3, May 2026.
We investigated neuropathological manifestations of hypothermia in 168 cases. Patients aged 65 years or more constituted 80% of the total cohort. Alzheimer's disease was the most common comorbidity, affecting 40% of all patients. Abstract There is a paucity of autopsy‐based studies providing detailed neuropathological characteristics of fatal ...
Shojiro Ichimata, Koji Yoshida, Ryo Tanaka   +2 more
wiley   +1 more source

E3 ligase AREL1 controls perinuclear localization of lysosomes and supports Purkinje cell survival. [PDF]

EMBO J
Jiang L, Tang J, Zhang YF, Zou WX, Deng G, Tian N, Zhao X, Han L, Liu K, Song BL, Luo J.   +10 more
europepmc   +1 more source

Regional cerebellar structural deficits distinguish psychostimulant‐free ADHD youth with and without familial risk for bipolar I disorder: a cross‐sectional morphometric analysis

Journal of Child Psychology and Psychiatry, Volume 67, Issue 5, Page 766-776, May 2026.
Background Although attention‐deficit/hyperactivity disorder (ADHD) with familial risk for bipolar I disorder (BD) may represent a more severe illness conferring greater risk for developing BD, associated neurostructural substrates remain poorly understood.
Biqiu Tang, L. Rodrigo Patino, Wenjing Zhang, Su Lui, Melissa P. DelBello, Robert K. McNamara   +5 more
wiley   +1 more source

Subtle changes in Purkinje cell firing in Purkinje cell-specific <i>Dyt1 ΔGAG</i> knock-in mice. [PDF]

Dystonia
Xing H, Girdhar P, Liu Y, Yokoi F, Vaillancourt DE, Li Y.   +5 more
europepmc   +1 more source

Viewpoint: spinocerebellar ataxias as diseases of Purkinje cell dysfunction rather than Purkinje cell loss. [PDF]

Front Mol Neurosci, 2023
Kapfhammer JP, Shimobayashi E.
europepmc   +1 more source

Molecular insights into electroreceptor ribbon synapses from differential gene expression in sturgeon lateral line organs

Journal of Anatomy, Volume 248, Issue 5, Page 784-805, May 2026.
The expression of various genes involved in synapse development, stability and/or function was studied in developing mechanosensory neuromasts and electrosensory ampullary organs in sterlet sturgeon. Most were shared, including Slc17a8, Slc1a3 and Nrxn3, but Cbln18 was neuromast‐restricted and Tulp1 was ampullary organ‐restricted.
Alexander S. Campbell, Martin Minařík, David Buckley, Tanmay Anand, David Gela, Martin Pšenička, Clare V. H. Baker   +6 more
wiley   +1 more source

FOXP genes regulate Purkinje cell diversity and cerebellar morphogenesis. [PDF]

Nat Neurosci
Khouri-Farah N, Guo Q, Perry TA, Dussault R, Li JYH.   +4 more
europepmc   +1 more source