Results 11 to 20 of about 2,825 (207)
Photoselection and circular dichroism in the purple membrane
Biophysical Journal, 1982 The transient dichroic ratio D = delta A parallel/delta A perpendicular has been measured in the visible absorption region of bacteriorhodopsin in purple membrane by a flash photolysis method.
Godfrey, R.E.
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Electrodichroism of Purple Membrane Ionic Strength Dependence
Biophysical Journal, 1986 The dichroism of purple membrane suspension was measured in dc and ac electric fields. From these measurements three parameters can be obtained: the permanent dipole moment, μ, the electrical polarizability, α, and the retinal angle, δ, (relative to the ...
Fricsovszky, G., Meszéna, G., Papp, E.
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Light-induced reorientation in the purple membrane
Biophysical Journal, 1993 Reorientation of bacteriorhodopsin in the native purple membrane was studied by time-resolved linear dichroism spectroscopy (TRLD) over the millisecond time regime. The time responses observed in TRLD are distinctly different from the isotropic transient
Wan, C., Qian, J., Johnson, C.K.
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Protein-Protein Interaction in Purple Membrane [PDF]
Physical Review Letters, 2009 We present experimental evidence for a long-range protein-protein interaction in purple membrane (PM). The interprotein dynamics were quantified by measuring the spectrum of the acoustic phonons in the 2D bacteriorhodopsin (BR) protein lattice using inelastic neutron scattering. Phonon energies of about 1 meV were determined.
Rheinstädter, M. C. +3 more
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Flash spectroscopy of purple membrane
Biophysical Journal, 1987 Flash spectroscopy data were obtained for purple membrane fragments at pH 5, 7, and 9 for seven temperatures from 5 degrees to 35 degrees C, at the magic angle for actinic versus measuring beam polarizations, at fifteen wavelengths from 380 to 700 nm, and for about five decades of time from 1 microsecond to completion of the photocycle. Signal-to-noise
Xie, A.H., Nagle, J.F., Lozier, R.H.
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Reversible Photolysis of the Purple Complex in the Purple Membrane of Halobacterium halobium [PDF]
European Journal of Biochemistry, 1973 A suspension of the purple membrane from Halobacterium halobium in concentrated salt solutions saturated with diethylether is bleached by light. During this process, the purple complex is converted in to a compound absorbing maximally at 412 nm (412‐nm complex). The purple complex reappears in the dark with a rate constant of 0.04 s−1 at 20°C.
D, Oesterhelt, B, Hess
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source