Results 51 to 60 of about 262,730 (211)

Behavior of Hydrated Lipid Bilayers at Cryogenic Temperatures

Frontiers in Chemistry, 2020
Neutron diffraction was used to study the behavior of water present in phospholipid multilamellar stacks from 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC) at cryogenic temperatures.
Jakob Meineke, Martin Weik, Giuseppe Zaccai, Giuseppe Zaccai, Giovanna Fragneto   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Understanding the molecular regulation of flavonoid 3’-hydroxylase in anthocyanin synthesis: insights from purple qingke

BMC Genomics
Background The Flavonoid 3’-hydroxylase gene(F3’H) is an important structural gene in the anthocyanin synthesis pathway of plants, which has been proven to be involved in the color formation of organs such as leaves, flowers, and fruits in many plants ...
Lupeng Chen, Youhua Yao, Yongmei Cui, Xin Li, Likun An, Yixiong Bai, Xiaohua Yao, Kunlun Wu   +7 more
doaj   +1 more source

Analysis of protein kinase C (HcPKC) gene expression and single-nucleotide polymorphisms related to inner shell color traits in Hyriopsis cumingii

BMC Genomic Data, 2022
Background Protein kinase C (PKC) is a multifunctional serine and PKC can phosphorylate serine residues in the cytoplasmic domain of tyrosinase, thereby regulating the activity of tyrosinase.
Mengying Zhang, Xiajun Chen, Jinpan Zhang, Baiying Guo, Jiale Li, Zhiyi Bai   +5 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

An intelligent active polylactic acid/gelatin nanofibrous membrane with Janus structure for meat freshness monitoring and preservation

Food Chemistry: X
Real-time monitoring of food freshness and extending its shelf life are crucial for reducing food waste and enhancing food quality and safety. In this study, an intelligent active food packaging with Janus structure was fabricated by sequentially ...
Xingzi Lan, Xinyu Chen, Jian Zhang, Yue Qiu, Wei Lan, Yadong Tang   +5 more
doaj   +1 more source

Bactericidal and Anti-Biofilm Activity of Ethanol Extracts Derived from Selected Medicinal Plants against Streptococcus pyogenes

Molecules, 2019
Background: There is a growing interest in medicinal plants which have been traditionally used for the treatment of human infections. This study assessed 14 ethanol extracts (EEs) on bacterial growth and biofilm formation of Streptococcus pyogenes ...
Niluni M. Wijesundara, H. P. Vasantha Rupasinghe   +1 more
doaj   +1 more source

The Effect of Bacterioruberin Deletion on Production of Bacteriorhodopsin in Halobacterium salinarum R1 [PDF]

Journal of Pure and Applied Chemistry Research, 2018
Bacteriorhodopsin is a retinal protein located in purple membrane of Halobacterium salinarum which acts as light-dependent proton pump. Bacterioruberin is a by-product in bacteriorhodopsin biosynthesis pathway in Halobacterium salinarum.
Abbas Karimi Fard, Ali Asghar Deldar, Saeed Sedaghat   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source