Results 131 to 140 of about 116,128,661 (298)

The Human Side of Purpose: Where Values Become Value in Benefit Corporations

open access: yes
reservedLa presente tesi esplora il lato umano del purpose nelle Benefit Corporations, analizzando come i valori dichiarati si traducano in valore concreto per le persone all’interno dell’organizzazione.
SQUIZZATO, SARAH
core  

Origins of Purpose in Life: Refining our Understanding of a Life Well Lived

open access: yesPsychological Topics, 2009
Purpose can be characterized as a central, self-organizing life aim. Central in that when present, purpose is a predominant theme of a person’s identity.
Todd B. Kashdan, Patrick E. McKnight
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The Calm Before the Storm? - Anticipating the Arrival of General Purpose Technologies [PDF]

open access: yes
This paper presents a Schumpeterian quality-ladder model incorporating the impact of new General Purpose Technologies (GPTs). GPTs are breakthrough technologies with a wide range of applications, opening up new innovational complementarities. In contrast
Daniel Schiess, Roger Wehrli
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Chair of landscape architecture : Estonian University of Life Sciences [PDF]

open access: yes, 2018
BookWelcome to the chair of Landscape Architecture at the Estonian University of Life Sciences. This book has been prepared as an introduction to our chair and should give you an insight into our teaching programme and examples of students’ works ...
Estonian University of Life Sciences. Chair of Landscape Architecture
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Purpose-driven organizations: a reality to understand

open access: yes
reservedDai primi anni 2000 e a seguito delle ultime crisi avvenute nei nostri sistemi, i temi riguardanti le organizzazioni si sono sempre più concentrati su aspetti quali la sostenibilità e l’impatto che le aziende possono avere all’interno del ...
SEMENZATO, ALICE
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy