Results 141 to 150 of about 5,869,077 (304)
“The Authority to Interpret, the Purpose of Universities, and the Giving of Awards, Honors, or Platforms by Catholic Universities: Some Thoughts on ‘Catholics in Political Life’,” [PDF]
, 2011 With its June 2004 statement Catholics in Political Life, the United States Conference of Catholic Bishops opened an important and far-reaching discussion about how Catholic individuals ought to comport themselves in political life, and-indirectly-about ...
Baur, Michael
core
Gambling addiction and life meaning
, 1999 Addictive Gambling has plagued mankind for thousands of years. However, it has only recently been studied extensively. One proposed cause for addiction, which has been used in studying alcohol and drug abuse, is a lack of meaning in the addict\u27s life.
Plesh, Andrew Bohdan
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Rangatahi Wahine: Overcoming the odds – preliminary results [PDF]
, 2003 The purpose of my research was to identify factors that have contributed to the development of resilience in young Māori girls’ lives. Incorporated into this was an exploration of their psychosocial competence makeup, to see whether their sense of ...
Merritt, Kiri
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Journal für Psychologie, 2008 Are Germans suffering from a crisis of meaning – as supposed by Chancellor Merkel in 2005? Following a short introduction to meaning research, and differentiations of the construct of meaning in life, results of a representative study among 603 Germans ...
Tatjana Schnell
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Critical Public HealthPurpose in Life (PIL) is a fundamental element of psychological well-being linked to various health outcomes and behaviors, including physical activity. However, the mechanisms underlying this relationship remain unclear.
Zhanjia Zhang, Zhonghui He, Xin Qi
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source