Results 51 to 60 of about 803,393 (302)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Fair Dealing for the Purpose of Education: York University v The Canadian Copyright Licensing Agency

open access: yes, 2021
In York University v The Canadian Copyright Licensing Agency (2020), the Federal Court of Appeal was confronted with two issues at the heart of ongoing debates in Canadian copyright law.
Chapdelaine, Pascale
core   +1 more source

Characteristic Study of a Valve-Matched Flow Single-Piston Miniature Water-Hydraulic Pump

open access: yesIEEE Access
A miniature single-piston valve flow-matching water-hydraulic pump is described in this paper, which designs with a unique double-face cam mechanism to achieve the reciprocating motion of the piston and a new flow-matching valve to adapt to the ...
Tong Xing   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Design and Characteristic Research on Variable Displacement Mechanism of Two-Dimensional (2D) Bivariable Pump

open access: yesEnergies
In a hydraulic system, a micro variable pump is required to be high pressure and high speed, and this work presents a new type of 2D bivariable pump structure in which the worm gear and worm mechanism are used to rotate the cylinder block to change the ...
Tong Xing, Xu Ji, Zeri Yang, Jian Ruan
doaj   +1 more source

Estimation of the Time-Varying High-Intensity Heat Flux for a Two-Layer Hollow Cylinder

open access: yesEnergies, 2018
Gun barrels are subjected to time-varying high-intensity heat flux under multiple firing, which may damage the material and limit the overall performance of the gun.
Lihui Zhang   +5 more
doaj   +1 more source

Effect of texture evolution on corrosion resistance of AZ80 magnesium alloy subjected to applied force in simulated body fluid

open access: yesMaterials Research Express, 2020
The electrochemical corrosion behavior of a rolled AZ80 magnesium alloy after pre-compressive strain along different orientation in a simulated body fluid (SBF) was investigated by immersion test for 48 h. The results showed that the corrosion resistance
Ying Xiong   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Periodization of the development of public preschool education of children of non-Russian nationalities in the RSFSR (1917 – early 1930s.)

open access: yesРазвитие образования, 2023
The article presents the results of studying the organization of public preschool education of children of non-Russian nationalities in the RSFSR. The purpose of the study was to study the development of public preschool education of children of non ...
Olga V. Bodenova
doaj   +1 more source

The purpose of science education

open access: yesNordina: Nordic Studies in Science Education, 2022
This study used a quantitative deductive approach based on Biesta’s functions of education and Roberts’ curriculum emphases to analyse the purposes that are stressed in the Swedish science syllabuses in lower and upper secondary school.
Eva Knekta, Pia, Christina Ottander
doaj   +1 more source

Home - About - Disclaimer - Privacy