Results 71 to 80 of about 167,574,678 (311)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Self-esteem in girls: does physical education make a difference [PDF]
, 2002 vi, 54 leaves ; 29 cm. --The purpose of this study was to determine whether participation in a girls' physical education class can contribute to the development of self-esteem.
Howe, Lori +1 more
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Character matters : central office administrators' perceptions of character education [PDF]
, 2004 vii, 87 leaves ; 29 cm. --In recent years there has been increasing pressure all across North America for schools to focus more on character education. This study examines one District's response to character education through the implementation of the
University of Lethbridge. Faculty of Education +1 more
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Current Science, 2018 During interactions with faculty colleagues and scientists at HCU, IISER and NCL Pune as well as other institutions where I have given lectures and attended conferences, I often hear the record playing, ‘it’s very difficult to get students to attend seminars; they are not interested in research; we were far more motivated in our times, etc.’ This chain
openaire +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
State Board of Education of Ohio annual report
, 2008 Electronic coverage as of Dec.
Ohio. State Board of Education.
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Teacher perception of character education [PDF]
, 2009 ix, 95 leaves ; 29 cmThis study explores teachers’ understanding of character education, their perceived role in curriculum development, implementation effectiveness, and their teaching practices.
Tuff, Lone +1 more
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source