Results 71 to 80 of about 803,393 (302)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Complex Sentences: Searching for the Purpose of Education Inside a Massachusetts State Prison

open access: yes, 2017
While policy makers and scholars often measure the success of prison education programs by quantitative outcomes such as recidivism and post-release employment, there is a gap in the literature with regard to how these programs facilitate community ...
Clint Smith
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Analytical Modeling and Experimental Study on Dynamic Characteristics of 2-D Piston Flowmeter

open access: yesIEEE Access
Dynamic flow measurement represents a critical and challenging research topic in hydraulic engineering. This paper briefly reviews state-of-the-art techniques for dynamic flow measurement, and presents a positive-displacement flowmeter scheme based on a ...
Ruiyi Shi   +3 more
doaj   +1 more source

M. M. Bakhtin as a University Professor

open access: yesDialogic Pedagogy, 2018
This article presents M. M. Bakhtin as a University professor through his own views of on the nature of university teaching: lecturing, seminars and colloquia, engaging students in debates and reflexive analysis of literary texts, “scientific thinking ...
Nikolai L Vasiliev
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

'Eternobee' developing the twofold purpose of education; Curriculum analysis

open access: yes, 2012
This paper introduces the purpose of education in an innovated form, it explains that education should focus on twofold purpose, and to develop that purpose a textbook named 'Eternobee' has been proposed initiatively in this study. But to understand what
Kamali, Lewa
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

How does Information Technology impact the methods, potential and purpose of education?

open access: yes, 2004
It is evident that information technology has affected changes to the methods, purpose and the perceived potential of education. While various authors differ in their opinion on the degree, desirability and destiny of these changes, all agree that change
Furneaux, Craig W.
core  

Education with a Purpose

open access: yesCurrent Science, 2018
During interactions with faculty colleagues and scientists at HCU, IISER and NCL Pune as well as other institutions where I have given lectures and attended conferences, I often hear the record playing, ‘it’s very difficult to get students to attend seminars; they are not interested in research; we were far more motivated in our times, etc.’ This chain
openaire   +1 more source

Home - About - Disclaimer - Privacy