Results 141 to 150 of about 167,732,555 (302)
Revista Latinoamericana de Estudios Educativos, 2014 Social studies have a contentious history as a school subject and this article begins with an overview of the historically competing viewpoints on the nature and purposes of social studies education in the North American context.
E. Wayne Ross +2 more
doaj
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The Purposes and Authority of Secular Education in the Monastic Rule of Cassiodorus
ReligionsThis article examines the purposes, origins, and authority of ‘secular education,’ or the seven liberal arts, in Cassiodorus’ Institutiones divinarum et saecularium litterarum. Whilst previous scholarship has argued that Cassiodorus traces the origins of
Marcus C. C. Rynningsjö Carlsén
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Athlete's perceptions of sport and education : a comparision of high school 4A basketball players and midget AAA hockey players in Alberta [PDF]
, 2003 x, 85 leaves ; 29 cm.This study focused on student athletes' perceptions of sport and education. The following research question was used to establish a framework for this thesis: Is there a significant difference in athletes' perceptions of sport and ...
Morgan, Robert +1 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Learning to teach English for academic purposes : some current training and development issues [PDF]
, 2002 In recent years, English for Academic Purposes (EAP) has become an expanding discipline within universities and further education institutions, both in Britain and worldwide.
Sharpling, Gerard
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Reflecting on the development of a new school subject: the development of technology education in New Zealand. [PDF]
, 2007 The last 10 years have seen the production of curricula in Australia, the United Kingdom, USA, Canada, Hong Kong and New Zealand that emphasise the importance of students developing technological literacy.
Jones, Alister
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