Results 71 to 80 of about 167,732,555 (302)

Le projet pédagogico-didactique de socialisation : perspective d’une socialisation démocratique pour l’enseignement-apprentissage des questions environnementales et de développement

open access: yesÉducation et Socialisation, 2018
This contribution is a reflection on the educational purposes as conditions of possibility of a pedagogical-didactic synergy in the analysis and the elaboration of educational situations. This reflection focuses, then, on the possibility of socialization
Melki Slimani   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Purposes of public school education in Oregon

open access: yes, 1955
Title from PDF caption (viewed on August 2, 2018).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

State Board of Education of Ohio annual report

open access: yes, 2008
Electronic coverage as of Dec.
Ohio. State Board of Education.
core  

The Impact of ChatGPT on English for Academic Purposes (EAP) Students’ Language Learning Experience: A Self-Determination Theory Perspective

open access: yesEducation sciences
This qualitative study explores the perceptions of English language students regarding the use of the generative AI tool, ChatGPT, as a supportive tool for English for Academic Purposes (EAP) students in a New Zealand university context.
Jin-Ming Du, Antonie Alm
semanticscholar   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

List of town school committees, boards of school visitors, boards of education; List of town school committees, boards of school visitors, boards of education, library directors; Directory of Connecticut public school officials

open access: yes, 1952
Vols. for 19-44 issued as Connecticut school document.; Two vols. issued as 1909 ( Mar. 1909, Dec. 1909); no vol. 1908 published?; Vols.
Connecticut. State Department of Education.
core   +1 more source

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