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Thrombotic thrombocytopenic purpura [PDF]
Nature Reviews Disease Primers, 2017 Thrombotic thrombocytopenic purpura (TTP; also known as Moschcowitz disease) is characterized by the concomitant occurrence of often severe thrombocytopenia, microangiopathic haemolytic anaemia and a variable degree of ischaemic organ damage, particularly affecting the brain, heart and kidneys.
Kremer Hovinga, Johanna A. +5 more
semanticscholar +9 more sources
Journal of Medical Case Reports, 2018 Background Incidences of immune thrombocytopenic purpura occur in 1 in every 1000–10,000 pregnancies accounting for 3% of all thrombocytopenic pregnancies.
Naser Al-Husban, Oqba Al-Kuran
doaj +2 more sources
Haematologica, 2019 Immune-mediated thrombotic thrombocytopenic purpura is characterized by severe thrombocytopenia and microangiopathic hemolytic anemia. It is primarily caused by immunoglobin G type autoantibodies against ADAMTS13, a plasma metalloprotease that cleaves ...
Elizabeth M. Staley +10 more
doaj +2 more sources
Novel Mutation of Upshaw-Schulman Syndrome Associated with Coarctation of Aorta in Palestinian Child [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2020 Upshaw-Schulman syndrome is a rare inherited form of thrombotic thrombocytopenic purpura disease caused by deficiency of ADAMTS13 and reversible by fresh frozen plasma infusions.
Mahdi Zaid +5 more
doaj +1 more source
Thrombotic Thrombocytopenic Purpura: Pathophysiology, Diagnosis, and Management
Journal of Clinical Medicine, 2021 Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and ischemic end organ injury due to microvascular platelet-rich thrombi.
S. Sukumar, B. Lämmle, S. Cataland
semanticscholar +1 more source
Journal of Medical Case Reports, 2023 Background Immune thrombocytopenic purpura and thrombotic thrombocytopenic purpura are both causes of thrombocytopenia. Recognizing thrombotic thrombocytopenic purpura is crucial for subsequent treatment and prognosis.
Hung-Chen Lin +6 more
doaj +1 more source
Frontiers in Immunology, 2022 For patients with autoimmune diseases, vaccination is controversial. The use of vaccination in patients with autoimmune diseases is controversial. There are many reports of secondary thrombotic thrombocytopenic purpura cases after various vaccinations ...
Yanming Cui, Jianbo Wei, Xiang Peng
doaj +1 more source
Journal of International Medical Research, 2022 A 33-year-old Chinese woman with a history of immune thrombocytopenic purpura presented with heavy menstrual bleeding. She was found to have thrombocytopenia, plasma ADAMTS13 activity of 0%, and positivity for the plasma ADAMTS13 inhibitor.
Hangping Ge +7 more
doaj +1 more source
Immune thrombocytopenic purpura [PDF]
Journal of Community Hospital Internal Medicine Perspectives, 2019 Immune thrombocytopenic purpura (ITP) is a bleeding disorder characterized by isolated thrombocytopenia (platelet count
Abir Zainal, Amr Salama, Richard Alweis
openaire +4 more sources
Immune Thrombocytopenic Purpura in a Patient with Covid-19
New England Journal of Medicine, 2020 Immune Thrombocytopenic Purpura and Covid-19 Immune thrombocytopenia with lower-extremity purpura, mucosal bleeding, and cerebral microhemorrhage developed during the clinical course in a 65-year-o...
A. Zulfiqar +3 more
semanticscholar +1 more source