Results 91 to 100 of about 43,474 (218)

Portal vein thrombosis after laparoscopic splenectomy: an ongoing clinical challenge. [PDF]

, 2005
ObjectivesPortal vein thrombosis (PVT) following open splenectomy is a potentially lethal complication with an incidence of up to 6%. The objective of this report is to describe our management of a recent laparoscopic case, discuss current therapies, and
Kee, Stephen T, Krummel, Thomas M, Mallory, Baird, Miniati, Douglas N, Padidar, Arash M   +4 more
core   +2 more sources

Autoimmunity and Novel Therapies in Immune-Mediated Thrombocytopenia [PDF]

, 2013
Immune-mediated thrombocytopenic purpura (ITP) is recognized as a cell-specific autoimmune disorder, yet, multifactorial in origin. The development of thrombocytopenia is well proven to be mediated by both humoral (anti-platelet antibodies) and cellular (
Shoenfeld, Yehuda, Toubi, Elias, Vadasz, Zahava, Yehudai, Dana   +3 more
core   +1 more source

Impact of COVID‐19 on paediatric care in Japan: Analysis of national health insurance claims data

Acta Paediatrica, Volume 114, Issue 6, Page 1135-1142, June 2025.
Abstract Aim To quantify the impact of the COVID‐19 pandemic on paediatric care use compared to adult care and identify affected subdomains. Methods Data from the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB) for six fiscal years (FY2016‐2021) were analysed.
Takuma Ohnishi, Mari Kinoshita, Satoshi Narumi   +2 more
wiley   +1 more source

Platelet count response to Helicobacter pylori eradication for idiopathic thrombocytopenic purpura in northeastern Brazil

Hematology, Transfusion and Cell Therapy, 2018
Background: Several studies have demonstrated that platelet counts in Helicobacter pylori-positive patients with chronic idiopathic thrombocytopenic purpura improved significantly after successful eradication of the infection.
Alzira Maria de Castro Barbosa, Rosangela Albuquerque Ribeiro, Cícero Ígor Simões Moura Silva, Francisco Will Saraiva Cruz, Orleancio Gomes Ripardo de Azevedo, Maria Helena da Silva Pitombeira, Lucia Libanez Campelo Braga   +6 more
doaj  

Involvement of the ADAMTS13–von Willebrand factor axis in acute kidney injury in mice with liver cirrhosis

Hepatology Research, Volume 55, Issue 6, Page 844-858, June 2025.
Abstract Aim Hepatorenal syndrome‐induced acute kidney injury (AKI) comprises AKI and liver cirrhosis (LC) and is a risk factor for poor prognoses of patients with LC. Decreased a disintegrin‐like metalloproteinase with thrombospondin type 1 motif 13 (ADAMTS13) activity and increased von Willebrand factor (vWF) antigen levels are associated with LC ...
Masayoshi Takami, Norihisa Nishimura, Kosuke Kaji, Nobuyuki Yorioka, Hiroyuki Masuda, Hiroaki Takaya, Koh Kitagawa, Shinya Sato, Tadashi Namisaki, Hitoshi Yoshiji   +9 more
wiley   +1 more source

The clinical use of platelet transfusions: A systematic literature review and meta‐analysis on behalf of the International Collaboration for Transfusion Medicine Guidelines

Transfusion, Volume 65, Issue 6, Page 1155-1169, June 2025.
Abstract Background Platelets are frequently transfused, but supply and potential harms highlight the importance of appropriate use. Study Design and Methods Our systematic review (SR) followed a predefined protocol. Eligible studies included SRs, randomized controlled trials (RCTs), and matched cohort observational studies between 1946 and March 2025.
Rachel Jug, Ursula La Rocca, Arwa Z. Al‐Riyami, Aarti Bathla, Ryan A. Metcalf, Sandra K. White, Simon J. Stanworth, Susan Nahirniak   +7 more
wiley   +1 more source

Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure. [PDF]

, 2009
Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure.
Borgulya, Gábor, Cervenak, László, Förhécz, Zsolt, Gombos, Tímea, Hársfalvi, Jolán, Jánoskuti, Lívia, Kunde, Jan, Makó, Veronika, Papassotiriou, Jana, Pozsonyi, Zoltán, Prohászka, Zoltán   +10 more
core   +1 more source

Púrpura trombopénica inmune : múltiples tratamientos para una enfermedad [PDF]

, 2012
En el present treball es descriuen les principals característiques clíniques de la purpura trombopènica immune, com ara, la distribució per sexes, edat, la presència d'hemorràgies en el moment del diagnòstic i la seva gravetat, la xifra de plaquetes i la
Lluch García, Rafael, Pujol Moix, Nuria, Universitat Autònoma de Barcelona. Departament de Medicina, Universitat Autònoma de Barcelona. Facultat de Medicina   +3 more
core  

Clinical factors and biomarkers predict outcome in patients with immune-mediated thrombotic thrombocytopenic purpura

Haematologica, 2019
Immune-mediated thrombotic thrombocytopenic purpura is characterized by severe thrombocytopenia and microangiopathic hemolytic anemia. It is primarily caused by immunoglobin G type autoantibodies against ADAMTS13, a plasma metalloprotease that cleaves ...
Elizabeth M. Staley, Wenjing Cao, Huy P. Pham, Chong H. Kim, Nicole K. Kocher, Lucy Zheng, Radhika Gangaraju, Robin G. Lorenz, Lance A. Williams, Marisa B. Marques, X. Long Zheng   +10 more
doaj   +1 more source

Thrombotic microangiopathies: thrombotic thrombocytopenic purpura / hemolytic uremic syndrome [PDF]

, 2010
Thrombotic microangiopathies (TMAs) are pathological conditions characterized by generalized microvascular occlusion by platelet thrombi, thrombocytopenia, and microangiopathic hemolytic anemia.
Mastroianni Kirsztajn, Gianna, Polito, Maria Goretti   +1 more
core   +2 more sources