Results 91 to 100 of about 43,401 (230)

Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. [PDF]

, 2009
The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome.
Hársfalvi, Jolán, Molvarec, Attila, Gombos, Tímea, Udvardy, Miklós László, Cervenak, László, Derzsy, Zoltán, Prohászka, Zoltán, Rigó, János, Bõze, Tamás, Makó, Veronika   +9 more
core   +1 more source

Hereditary Thrombotic Thrombocytopenic Purpura in a 9-Month-old: Diagnosing and Managing an Ultra-rare Disorder [PDF]

, 2020
Hereditary thrombotic thrombocytopenic purpura is an ultra-rare disorder caused by biallelic mutations in the ADAMTS13 gene. Because it can be difficult to diagnose, plasma ADAMTS13 activity assessment should be considered in patients with ...
Kohorst, Mira A, Kirk D. Wyatt, Hendrika Anette van Dorland, Rachel M. Hurley, Arndt, Carola A S, Lea M. Coon, Carola A.S. Arndt, Mira A. Kohorst, Wyatt, Kirk D, Coon, Lea M, Hurley, Rachel M, van Dorland, Hendrika Anette   +11 more
core   +2 more sources

Wiskott–Aldrich syndrome that was initially diagnosed as immune thrombocytopenic purpura secondary to a cytomegalovirus infection

SAGE Open Medical Case Reports, 2018
Wiskott–Aldrich syndrome is a rare X-linked recessive disease resulting from variations in the WAS gene. Wiskott–Aldrich syndrome is sometimes difficult to differentiate from immune thrombocytopenic purpura. A 2-month-old boy was admitted to our hospital
Ryota Kaneko, Shohei Yamamoto, Naoko Okamoto, Kosuke Akiyama, Ryosuke Matsuno, Daisuke Toyama, Akihiro Hoshino, Kohsuke Imai, Keiichi Isoyama   +8 more
doaj   +1 more source

Immune Thrombocytopenia as a Consequence of Rocky Mountain Spotted Fever

Case Reports in Oncology, 2017
Primary immune thrombocytopenia (ITP) – also called idiopathic thrombocytopenic purpura or immune thrombocytopenic purpura – is an acquired thrombocytopenia caused by autoantibodies against platelet antigens.
Cherisse Baldeo, Karan Seegobin, Lara Zuberi   +2 more
doaj   +1 more source

Human Herpesvirus 8 Causes a Wide Spectrum of Disease in Liver Transplant Recipients and May be Donor Derived: Case Series and Systematic Review of an Emerging Challenge

Transplant Infectious Disease, EarlyView.
Among 135 cases of post‐liver transplant HHV8 disease (4 from NSW), presentations varied, and mortality was high (44%). Donor screening was rare, and donor‐derived infection was suspected in 33%. Survival improved with mTORi, reduced immunosuppression, chemotherapy, and, for non‐KS disease, donor screening. ABSTRACT Background Human herpesvirus 8 (HHV8)
Karen M. J. Waller, Sudarshan Arvind, Simone I. Strasser, Ken Liu, Geoff W. McCaughan, David G. Bowen, Madeleine Gill, Rebecca Davis, William Rawlinson, Sacha Stelzer‐Braid, Geoff Watson, Vinay Vanguru, Tina Marinelli   +12 more
wiley   +1 more source

Idiopathic Thrombocytopenic Purpura after Mastectomy and Axillary Lymph Node Dissection

Case Reports in Surgery, 2014
First described in 1916, idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease resulting in the destruction of platelets. Here, we present a case of an 85-year-old patient diagnosed with invasive ductal carcinoma of the breast whose surgical
Wil L. Santivasi, Meghan M. Routt, Alicia M. Terando   +2 more
doaj   +1 more source

Clinical predictors of mortality in immune thrombotic thrombocytopenic purpura: A National Inpatient Sample analysis

British Journal of Haematology, EarlyView.
Anand Shah, Christopher Chen, Ilana Pyatetsky, Shruti Chaturvedi, Ankit S. Shah   +4 more
wiley   +1 more source

Functional validation of a modified platelet desialylation test for immune and hereditary thrombocytopenias

Transfusion Medicine, EarlyView.
Abstract Background Thrombocytopenia arises from heterogeneous inherited and acquired disorders, and identifying the underlying platelet clearance mechanisms remains challenging. Platelet desialylation, characterised by loss of sialic acid and consequent exposure of terminal β‐galactose residues recognised by the Ashwell–Morell receptor, represents an ...
Karen Nogueira Chinoca Ziza, Thamy Caroline Silva, Mateus Domentino, Marina Cavalcanti Albuquerque Veiga Conrado, João Vitor Bernardo Oliveira, Felipe Augusto Rós, Caroline Gabe, Elyse Moritz, Akemi Chiba, Paula Villaça, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Dante Langhi, Carla Luana Dinardo   +14 more
wiley   +1 more source

Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom [PDF]

, 2010
Atypical haemolytic uraemic syndrome (aHUS) is associated with a poor prognosis with regard to survival at presentation, recovery of renal function and transplantation.
Sam Machin, ?, ?, Machin, Sam, Tim H. J. Goodship, Goodship, Tim H J, Stephen J. Wigmore, Taylor, C Mark, Wigmore, Stephen J, C. Mark Taylor   +8 more
core   +1 more source

Hereditary thrombotic thrombocytopenic purpura and the hereditary TTP registry [PDF]

, 2013
Hereditary thrombotic thrombocytopenic purpura, Upshaw-Schulman syndrome, ADAMTS13 Hereditary thrombotic thrombocytopenic purpura (TTP), also known as Upshaw-Schulman syndrome, is a rare recessively inherited disease.
J. N. George, J. A. Kremer Hovinga, Quist-Paulsen, P., I. Hrachovinova, von Krogh, A.-S., Fujimura, Y., Mansouri Taleghani, Magnus, Knöbl, P. N., R. Schneppenheim, Hrachovinová, I., P. Quist-Paulsen, Kremer Hovinga, Johanna Anna, M. Mansouri Taleghani, George, J. N., B. Lämmle, A.-S. von Krogh, Y. Fujimura, Lämmle, Bernhard, P. N. Knöbl, Schneppenheim, R.   +19 more
core   +1 more source