Results 21 to 30 of about 79,367 (221)

Vincristine as an Adjunct to Therapeutic Plasma Exchange for Thrombotic Thrombocytopenic Purpura: A Single-Institution Experience

Balkan Medical Journal, 2018
Background: Thrombotic thrombocytopenic purpura is a potentially life-threatening condition. Although the introduction of therapeutic plasma exchange has reduced mortality rates from over 90% to 10%-20%, approximately 40% of patients relapse, and ...
Seniz Öngören, Ayşe Salihoğlu, Tuğçe Apaydın, Sevil Sadri, Ahmet Emre Eşkazan, Muhlis Cem Ar, Tuğrul Elverdi, Zafer Başlar, Yıldız Aydın, Teoman Soysal   +9 more
doaj   +1 more source

Human neutrophil peptides and complement factor Bb in pathogenesis of acquired thrombotic thrombocytopenic purpura

Haematologica, 2016
Acquired thrombotic thrombocytopenic purpura is primarily caused by the deficiency of plasma ADAMTS13 activity resulting from autoantibodies against ADAMTS13.
Wenjing Cao, Huy P. Pham, Lance A. Williams, Jenny McDaniel, Rance C. Siniard, Robin G. Lorenz, Marisa B. Marques, X. Long Zheng   +7 more
doaj   +1 more source

Hereditary thrombotic thrombocytopenic purpura

Haematologica, 2019
The first description of thrombotic thrombocytopenic purpura (TTP) by Moschowitz was published nearly 100 years ago.[1][1] This was likely to have been an immune-mediated TTP episode and the author described multi organs affected with worsening ...
M. Scully
semanticscholar   +2 more sources

Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura

New England Journal of Medicine, 2019
BACKGROUND In acquired thrombotic thrombocytopenic purpura (TTP), an immune‐mediated deficiency of the von Willebrand factor–cleaving protease ADAMTS13 allows unrestrained adhesion of von Willebrand factor multimers to platelets and microthrombosis ...
M. Scully, S. Cataland, F. Peyvandi, P. Coppo, P. Knöbl, J. Hovinga, A. Metjian, J. de la Rubia, K. Pavenski, F. Callewaert, Debjit Biswas, H. de Winter, R. Zeldin   +12 more
semanticscholar   +1 more source

Sequential occurrence of thrombotic thrombocytopenic purpura, essential thrombocythemia, and idiopathic thrombocytopenic purpura in a 42-year-old African-American woman: a case report and review of the literature

Journal of Medical Case Reports, 2012
Introduction Thrombotic thrombocytopenic purpura and idiopathic thrombocytopenic purpura are two well recognized syndromes that are characterized by low platelet counts. In contrast, essential thrombocythemia is a myeloproliferative disease characterized
Farhat Mirna H, Kuriakose Philip, Jawad Michael, Hanbali Amr   +3 more
doaj   +1 more source

IDIOPATHIC TROMBOCYTOPENIC PURPURA DURING PREGNANCY.OBSTETRICS AND PERENATAL RISKS

Акушерство, гинекология и репродукция, 2016
Idiopathic thrombocytopenic purpura is a relatively rare disease, especially during pregnancy. Currently, there are many ways of diagnostics, monitoring and treatment of patients.
V. B. Tskhay, E. K. Grebennikova
doaj   +1 more source

Platelet count response to Helicobacter pylori eradication for idiopathic thrombocytopenic purpura in northeastern Brazil

Hematology, Transfusion and Cell Therapy, 2018
Background: Several studies have demonstrated that platelet counts in Helicobacter pylori-positive patients with chronic idiopathic thrombocytopenic purpura improved significantly after successful eradication of the infection.
Alzira Maria de Castro Barbosa, Rosangela Albuquerque Ribeiro, Cícero Ígor Simões Moura Silva, Francisco Will Saraiva Cruz, Orleancio Gomes Ripardo de Azevedo, Maria Helena da Silva Pitombeira, Lucia Libanez Campelo Braga   +6 more
doaj   +1 more source

The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: key findings at enrollment until 2017

Haematologica, 2019
Congenital thrombotic thrombocytopenic purpura is an autosomal recessive inherited disease with a clinically heterogeneous course and an incompletely understood genotype-phenotype correlation.
H. A. van Dorland, M. M. Taleghani, K. Sakai, K. Friedman, J. George, I. Hrachovinova, P. Knöbl, A. von Krogh, R. Schneppenheim, I. Aebi-Huber, L. Bütikofer, C. Largiadèr, Z. Cermakova, K. Kokame, T. Miyata, H. Yagi, Deirdra R. Terrell, S. Vesely, M. Matsumoto, B. Lämmle, Y. Fujimura, J. K. Kremer Hovinga   +21 more
semanticscholar   +1 more source

Campylobacter Jejuni and Thrombotic Thrombocytopenic Purpura

Canadian Journal of Gastroenterology, 1990
Gastrointestinal bacterial infections could be associated with multisystem complication due to the thrombotic phenomena. This paper reports the association of Campylobacter jejuni infection and thrombotic thrombocytopenic purpura, and describes a new ...
Roman Jaeschke, E Jan Irvine, Jane Moore, John Kelton   +3 more
doaj   +1 more source

Tuberculosis associated thrombocytopenic purpura: effectiveness of antituberculous therapy

Hematology Reports, 2009
Association of immune thrombocytopenic purpura and tuberculosis is a rare condition. In 5 patients presenting with this association, anti-tuberculous therapy was effective on both tuberculosis and thrombocytopenia suggesting a causal relationship between
Raphael Borie, Claire Fieschi, Eric Oksenhendler, Lionel Galicier   +3 more
doaj   +1 more source