Results 21 to 30 of about 78,453 (209)

Hereditary thrombotic thrombocytopenic purpura

Haematologica, 2019
The first description of thrombotic thrombocytopenic purpura (TTP) by Moschowitz was published nearly 100 years ago.[1][1] This was likely to have been an immune-mediated TTP episode and the author described multi organs affected with worsening ...
M. Scully
semanticscholar   +2 more sources

Human neutrophil peptides and complement factor Bb in pathogenesis of acquired thrombotic thrombocytopenic purpura

Haematologica, 2016
Acquired thrombotic thrombocytopenic purpura is primarily caused by the deficiency of plasma ADAMTS13 activity resulting from autoantibodies against ADAMTS13.
Wenjing Cao, Huy P. Pham, Lance A. Williams, Jenny McDaniel, Rance C. Siniard, Robin G. Lorenz, Marisa B. Marques, X. Long Zheng   +7 more
doaj   +1 more source

Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura

New England Journal of Medicine, 2019
BACKGROUND In acquired thrombotic thrombocytopenic purpura (TTP), an immune‐mediated deficiency of the von Willebrand factor–cleaving protease ADAMTS13 allows unrestrained adhesion of von Willebrand factor multimers to platelets and microthrombosis ...
M. Scully, S. Cataland, F. Peyvandi, P. Coppo, P. Knöbl, J. Hovinga, A. Metjian, J. de la Rubia, K. Pavenski, F. Callewaert, Debjit Biswas, H. de Winter, R. Zeldin   +12 more
semanticscholar   +1 more source

Sequential occurrence of thrombotic thrombocytopenic purpura, essential thrombocythemia, and idiopathic thrombocytopenic purpura in a 42-year-old African-American woman: a case report and review of the literature

Journal of Medical Case Reports, 2012
Introduction Thrombotic thrombocytopenic purpura and idiopathic thrombocytopenic purpura are two well recognized syndromes that are characterized by low platelet counts. In contrast, essential thrombocythemia is a myeloproliferative disease characterized
Farhat Mirna H, Kuriakose Philip, Jawad Michael, Hanbali Amr   +3 more
doaj   +1 more source

IDIOPATHIC TROMBOCYTOPENIC PURPURA DURING PREGNANCY.OBSTETRICS AND PERENATAL RISKS

Акушерство, гинекология и репродукция, 2016
Idiopathic thrombocytopenic purpura is a relatively rare disease, especially during pregnancy. Currently, there are many ways of diagnostics, monitoring and treatment of patients.
V. B. Tskhay, E. K. Grebennikova
doaj   +1 more source

The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: key findings at enrollment until 2017

Haematologica, 2019
Congenital thrombotic thrombocytopenic purpura is an autosomal recessive inherited disease with a clinically heterogeneous course and an incompletely understood genotype-phenotype correlation.
H. A. van Dorland, M. M. Taleghani, K. Sakai, K. Friedman, J. George, I. Hrachovinova, P. Knöbl, A. von Krogh, R. Schneppenheim, I. Aebi-Huber, L. Bütikofer, C. Largiadèr, Z. Cermakova, K. Kokame, T. Miyata, H. Yagi, Deirdra R. Terrell, S. Vesely, M. Matsumoto, B. Lämmle, Y. Fujimura, J. K. Kremer Hovinga   +21 more
semanticscholar   +1 more source

Development and validation of a predictive model for death in acquired severe ADAMTS13 deficiency-associated idiopathic thrombotic thrombocytopenic purpura: the French TMA Reference Center experience

Haematologica, 2012
Background Acquired thrombotic thrombocytopenic purpura is still associated with a 10–20% death rate. It has still not been possible to clearly identify early prognostic factors of death.
Ygal Benhamou, Cyrielle Assié, Pierre-Yves Boelle, Marc Buffet, Rana Grillberger, Sandrine Malot, Alain Wynckel, Claire Presne, Gabriel Choukroun, Pascale Poullin, François Provôt, Didier Gruson, Mohamed Hamidou, Dominique Bordessoule, Jacques Pourrat, Jean-Paul Mira, Véronique Le Guern, Claire Pouteil-Noble, Cédric Daubin, Philippe Vanhille, Eric Rondeau, Jean-Bernard Palcoux, Christiane Mousson, Cécile Vigneau, Guy Bonmarchand, Bertrand Guidet, Lionel Galicier, Elie Azoulay, Hanspeter Rottensteiner, Agnès Veyradier, Paul Coppo   +30 more
doaj   +1 more source

Characterization and treatment of congenital thrombotic thrombocytopenic purpura.

Blood, 2019
Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra-rare thrombomicroangiopathy caused by an inherited deficiency of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13).
F. Alwan, C. Vendramin, R. Liesner, A. Clark, W. Lester, T. Dutt, W. Thomas, R. Gooding, T. Biss, Henry G. Watson, N. Cooper, R. Rayment, T. Cranfield, J. J. Veen, Q. Hill, Sarah Davis, J. Motwani, N. Bhatnagar, Nicole Priddee, M. Dávid, Maeve P. Crowley, J. Alamelu, H. Lyall, J. Westwood, M. Thomas, M. Thomas, M. Scully, M. Scully   +27 more
semanticscholar   +1 more source

Campylobacter Jejuni and Thrombotic Thrombocytopenic Purpura

Canadian Journal of Gastroenterology, 1990
Gastrointestinal bacterial infections could be associated with multisystem complication due to the thrombotic phenomena. This paper reports the association of Campylobacter jejuni infection and thrombotic thrombocytopenic purpura, and describes a new ...
Roman Jaeschke, E Jan Irvine, Jane Moore, John Kelton   +3 more
doaj   +1 more source

Tuberculosis associated thrombocytopenic purpura: effectiveness of antituberculous therapy

Hematology Reports, 2009
Association of immune thrombocytopenic purpura and tuberculosis is a rare condition. In 5 patients presenting with this association, anti-tuberculous therapy was effective on both tuberculosis and thrombocytopenia suggesting a causal relationship between
Raphael Borie, Claire Fieschi, Eric Oksenhendler, Lionel Galicier   +3 more
doaj   +1 more source