Results 41 to 50 of about 78,453 (209)

Evaluation of the diagnostic performance of platelet-derived indices for the differential diagnosis of thrombocytopenia in pediatrics

Revista de la Facultad de Medicina, 2014
Background. Platelet-derived indices have a well-established correlation with the differential diagnosis of thrombocytopenia in adult-based research. These indices include mean platelet volume, platelet distribution width, and platelet-large cell ratio.
Nelson Hernando Aponte Barrios, Adriana Linares Ballesteros, Isabel Cristina Sarmiento Urbina, Gloria Inés Uribe Botero   +3 more
doaj   +1 more source

Graves’ disease-induced immune thrombocytopenic purpura in an African female: a case report

Journal of Medical Case Reports, 2023
Background Immune thrombocytopenic purpura is a condition associated with an unusual, unexplained, and sometimes very severe reduction in the level of platelets in the blood.
Kwabena Oteng Agyapong, Aba A. Folson, Kate Fiador, Cecilia Kootin-Sanwu, Martha Tufuor, Sally Afua Bampoh, Henrietta Fiscian, Roland Wonkyi   +7 more
doaj   +1 more source

Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini, Alla Nakonechna, Annick Barbaud, Sevim Bavbek, Gianfranco Calogiuri, Inmaculada Doña, Violeta Kvedariene, Jose Julio Laguna Martinez, Serena Liberati, Mauro Pagani, Antonino Romano   +10 more
wiley   +1 more source

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

Thrombotic thrombocytopenic purpura: Toward targeted therapy and precision medicine

Research and Practice in Thrombosis and Haemostasis, 2018
Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy characterized by severe congenital or immune‐mediated deficiency in ADAMTS13, the enzyme that cleaves von Willebrand factor multimers.
P. Coppo, A. Cuker, J. George
semanticscholar   +1 more source

Co‐Occurrence of HIV‐Susceptibility and ‐Protective HLA Alleles Is a Possible Contributor to the Development of Primary HIV‐Associated Thrombocytopenia (PHAT): A Cross‐Sectional Study

International Journal of Immunogenetics, EarlyView.
ABSTRACT Primary HIV‐associated thrombocytopenia (PHAT) is an isolated thrombocytopenia in HIV‐positive individuals in the absence of secondary causes. The presence of certain Human Leukocyte Antigens (HLA) has been linked to individuals’ immune response to HIV and the development of immune‐mediated thrombocytopenic disorders.
Walter J Janse van Rensburg, Anne‐Cecilia van Marle, Lomari Geertsema   +2 more
wiley   +1 more source

Caplacizumab for Acquired Thrombotic Thrombocytopenic Purpura.

New England Journal of Medicine, 2016
BACKGROUND Acquired thrombotic thrombocytopenic purpura (TTP) is caused by aggregation of platelets on ultralarge von Willebrand factor multimers. This microvascular thrombosis causes multiorgan ischemia with potentially life-threatening complications ...
F. Peyvandi, M. Scully, J. K. Kremer Hovinga, S. Cataland, P. Knöbl, Haifeng M. Wu, A. Artoni, J. Westwood, M. Mansouri Taleghani, B. Jilma, F. Callewaert, H. Ulrichts, C. Duby, Dominique Tersago   +13 more
semanticscholar   +1 more source

The Relationship Between Helicobacter Pylori Infection And Childhood Idiopathic Thrombocytopenic Purpura

مجلة كلية الطب, 2007
Background: Idiopathic thrombocytopenic purpura , a disorder characterized by autoantibody mediated platelets destruction causing decreased number of circulating platelets manifest as bleeding tendency.
Sawsan S. Abbas, Tariq M. Hadi
doaj  

Secondary immune thrombocytopenic purpura with renal cell carcinoma

IJU Case Reports, 2019
Introduction Several types of cancers are reported to induce secondary immune thrombocytopenia resembling immune thrombocytopenic purpura‐like syndrome. However, renal cell carcinoma‐induced immune thrombocytopenic purpura is an extremely rare phenomenon.
Shigeaki Nakazawa, Masataka Kawamura, Kosuke Nakano, Norichika Ueda, Hidefumi Kishikawa, Hirokazu Kashiwagi, Motohide Uemura, Ryoichi Imamura, Kenji Nishimura, Norio Nonomura   +9 more
doaj   +1 more source

Significance of Immature Platelet Fraction in Diagnosed Patients of the Immune Thrombocytopenic Purpura

Pakistan Armed Forces Medical Journal, 2022
Objective: Determination of significance of immature platelet fraction (IPF%) in diagnosed patients of Immune thrombocytopenic purpura (ITP). Study Design: It was a cross-sectional study.
Mohammad Shabih Haider, Asad Mahmood, Manzar Bozdar, Saima Zahir, Saadia Muzafar, Maliha Batool Bukhari   +5 more
doaj   +1 more source