Results 131 to 140 of about 46,143 (249)
Jun Zheng,1 Xiaohong Pan,2 Yiyun Jiang3 1Department of Rehabilitation, Nanxing Health Service Center, Shangcheng, Hangzhou, Zhejiang, 310000, People’s Republic of China; 2Tuberculosis Care Unit, Hospital of Integrated Traditional Chinese and Western ...
Zheng J, Pan X, Jiang Y
doaj
The ADAMTS131239–1253 peptide is a dominant HLA-DR1-restricted CD4+ T-cell epitope
Acquired thrombotic thrombocytopenic purpura is a rare and severe disease characterized by auto-antibodies directed against “A Disintegrin And Metalloproteinase with Thrombospondin type 1 repeats, 13th member" (ADAMTS13), a plasma protein involved in ...
Laurent Gilardin+19 more
doaj +1 more source
Clinical Dilemma in the Treatment of a Patient with Microangiopathic Haemolytic Anaemia, Thrombocytopaenia and Severe Hypertension [PDF]
While haemolytic uraemic syndrome in children is predominantly associated with Shiga toxin -producing Escherichia coli (typically 0157:H7), some cases occur without associated diarrhoea, or as the manifestation of an underlying disorder other than ...
Castro, I, Gomes, D, Viegas, V
core
Background Severe ADAMTS13 deficiency is a critical component of the pathogenesis of idiopathic thrombotic thrombocytopenic purpura but is found only in about 60% of patients clinically diagnosed with this disease.Design and Methods Over a period of 8 ...
Rahel Froehlich-Zahnd+11 more
doaj +1 more source
Plasma von Willebrand factor levels predict in-hospital survival in patients with acute-on-chronic liver failure [PDF]
BACKGROUND AND AIMS: Circulating levels of von Willebrand factor (vWF) predict mortality in patients with cirrhosis. We hypothesized that systemic inflammation in acute-on-chronic liver failure (ACLF) will stimulate endothelium, increase vWF levels, and ...
Amirtharaj, GJ+9 more
core +1 more source
We herein would like to report an interesting case of a patient who presented with anemia and thrombocytopenia combined with high serum Lactic Dehydrogenase where Thrombotic Thrombocytopenic Purpura was originally considered.
Panagiotis Andreadis+6 more
doaj +1 more source
The PLASMIC score for the prediction of a likelihood of a severe ADAMTS13 deficiency represents a valid pre-test diagnostic tool to identify patients with thrombotic thrombocytopenic purpura.
Giovanni Tiscia+17 more
doaj +1 more source
Purpura tronbotiko tronbozitopenikoaren berrikustea. Basurtuko ospitalean izandako kasuen analisia [PDF]
[EUS] Purpura tronbotiko tronbozitopenikoa (PTT) odoleko gaixotasun arraroa da, urteko 10 kasu/milioi prebalentziarekin eta 1 kasu berri/milioi-ko intzidentziarekin1.
De Ariño Hervas, Itziar
core
Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK [PDF]
Seasonal outbreaks of cutaneous and renal glomerular vasculopathy (CRGV) have been reported annually in UK dogs since 2012, yet the aetiology of the disease remains unknown. The objectives of this study were to explore whether any breeds had an increased
Cardwell, J M+5 more
core +1 more source
Pathophysiology of thrombotic thrombocytopenic purpura.
The discovery of a disintegrin-like and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS13) revolutionized our approach to thrombotic thrombocytopenic purpura (TTP).
J. E. Sadler
semanticscholar +1 more source