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THROMBOTIC THROMBOCYTOPENIC PURPURA
Annals of Internal Medicine, 1953Excerpt Thrombotic thrombocytopenic purpura is a rare disease of which only a few cases have been diagnosed ante mortem.4Because of the rarity of diagnosis, other than at the autopsy table, few lab...
Thomas W. Green, Waverly S. Green
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The Pathogenesis of Thrombotic Thrombocytopenic Purpura [PDF]
Seminars in Thrombosis and Hemostasis, 1979 The vascular lesions with microthrombi were studied in 12 patients with thrombotic thrombocytopenic purpura (TTP), diagnosed by the characteristic clinical and laboratory findings and confirmed histologically in each case. While defibrination was not observed, and with only minimal changes in the circulating levels of fibrinogen, fibrin degradation ...
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Thrombotic thrombocytopenic purpura in pregnancy
BJOG: An International Journal of Obstetrics & Gynaecology, 1982Summary. A 20 week primigravida with intrauterine fetal death and the rare occurrence of thrombotic thrombocytopenic purpura (TTP) in pregnancy is presented. Aprotinin has been used to overcome uterine inertia non‐responsive to oxytocin stimulation. TTP was successfully treated with repeated plasmaphereses.
M. Atlas +4 more
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Autoimmunity in Thrombotic Thrombocytopenic Purpura
Seminars in Thrombosis and Hemostasis, 2005In the last few years, an autoimmune hypothesis for the pathogenesis of thrombotic thrombocytopenic purpura (TTP) has been proposed often, with variable success because of inconsistent supporting data. We are now aware that at least one subgroup of TTP patients does present with pathogenic autoantibodies (i.e, anti-ADAMTS13); this group consequently is
Porta, Camillo +2 more
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Thrombotic Thrombocytopenic Purpura
JAMA: The Journal of the American Medical Association, 1982Though thrombotic thrombocytopenic purpura (TTP) is not a common disorder, having an estimated annual incidence of one per million population, it merits attention.1First, it afflicts those in the prime of life between the third and fourth decade. Second, it generally runs a fulminant course with mortality in excess of 8096.
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Thrombotic Thrombocytopenic Purpura
Annals of Internal Medicine, 1980Excerpt Originally described in 1925 (1), thrombotic thrombocytopenic purpura remained until recently a fulminating and rapidly fatal disorder. Fortunately, it has been rare.
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Thrombotic Thrombocytopenic Purpura
JAMA, 1981Thrombotic thrombocytopenic purpura (TTP) is an infrequent, sporadic, and highly fatal syndrome. Recent advances in therapy and insight into the pathogenesis of this disorder have dramatically changed its once poor prognosis. A reappraisal of the diagnosis, pathogenesis, and treatment of TTP is the subject of this article. (JAMA1981;246:1243-1246)
Sidney M. Crain, Abdul M. Choudhury
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Thrombotic thrombocytopenic purpura
The Journal of Pediatrics, 1962Summary Thrombotic thrombocytopenic purpura is a relatively uncommon clinical syndrome characterized by thrombocytopenia, hemolytic anemia, and neurologic abnormalities. The case presented followed an infection with rubeola. The patient had a complete remission for 6 months.
Mildred Schaffhausen +2 more
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Thrombotic thrombocytopenic purpura
JAAPA, 2021Lauren Collin, Zachary Lavender
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