Results 81 to 90 of about 22,169 (207)

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, Volume 8, Issue 12, December 2025.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source

Plasma von Willebrand factor levels predict in-hospital survival in patients with acute-on-chronic liver failure [PDF]

, 2016
BACKGROUND AND AIMS: Circulating levels of von Willebrand factor (vWF) predict mortality in patients with cirrhosis. We hypothesized that systemic inflammation in acute-on-chronic liver failure (ACLF) will stimulate endothelium, increase vWF levels, and ...
Amirtharaj, GJ, Balasubramanian, KA, Eapen, CE, Elias, E, Goel, A, Mackie, I, Prasanna, KS, Ramachandran, A, Sajith, KG, Zachariah, U   +9 more
core   +1 more source

Pseudotumor Cerebri and Hemolytic Uremic Syndrome, A Rare Association

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Hemolytic uremic syndrome can present with central nervous system involvement. Idiopathic intracranial hypertension (IIH) is among the possible neurological manifestations of HUS, and clinicians should remain vigilant for extrarenal complications while treating patients with HUS.
Aasim Ali, Armaghana Abdullah, Mukesh Kumar Sharma, Anousha Tanveer, Muhammad Abdullah Mushtaq, Muhammad Mujtaba, Summaya Mushtaq   +6 more
wiley   +1 more source

Idiopathic combined, autoantibody-mediated ADAMTS-13/factor H deficiency in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome in a 17-year-old woman: a case report

Journal of Medical Case Reports, 2011
Introduction Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome is a life-threatening condition with various etiopathogeneses. Without therapy approximately 90% of all patients die from the disease. Case presentation We report the case of a 17-
Patschan Daniel, Korsten Peter, Behlau Arne, Vasko Radovan, Heeg Malte, Sweiss Nadera, Müller Gerhard A, Koziolek Michael   +7 more
doaj   +1 more source

Редкое клиническое наблюдение тромботической тромбоцитопенической пурпуры у больной 16 лет [PDF]

, 2016
Описание случая диагностики и течения тромботической тромбоцитопенической пурпуры у девочки 16 ...
Бадосова, Т. В., Романова, Т. А., Чернявская, Е. К.   +2 more
core   +1 more source

Thrombocytopeniak. [PDF]

, 2014
Thrombocytopenia means low platelet count. This is the most frequent cause of bleeding abnormalities. Petechias, purpuras, mucosal bleeding are typical clinical findings.
Domján, Gyula, Gadó, Klára
core   +1 more source

Modern concepts of the platelet in health and disease [PDF]

, 1962
Thesis (M.D.)--Boston ...
Estes, J. Worth
core  

Thrombotic Thrombocytopenic Purpura Revisited: Upshaw Schulman Syndrome in a 20-Year-Old Male [PDF]

, 2012
Case Report A 20-year-old male with no significant past medical history presented to an outside hospital with a two-week history of progressive fatigue, malaise and decreased appetite. Prior to these events, he had been in his usual state of health with
Peiris, MD, Niluk, Wang, MD, Judy
core   +2 more sources

Clinical Dilemma in the Treatment of a Patient with Microangiopathic Haemolytic Anaemia, Thrombocytopaenia and Severe Hypertension [PDF]

, 2010
While haemolytic uraemic syndrome in children is predominantly associated with Shiga toxin -producing Escherichia coli (typically 0157:H7), some cases occur without associated diarrhoea, or as the manifestation of an underlying disorder other than ...
Castro, I, Gomes, D, Viegas, V
core  

Effect of blood groups on acquired and congenital thrombotic thrombocytopenic purpura and clinical correlation: Multi-center Turkish cohort study

Hematology, Transfusion and Cell Therapy
Background: Thrombotic thrombocytopenic purpura (TTP) is a microangiopathic hemolytic anemia associated with ADAMTS-13 deficiency, a cleaving protease of von Willebrand factor (vWF).
Cevat İlteriş Kıkılı, Damla Ortaboz, Melek Yanaşık, Muhlis Cem Ar, Sevgi Kalayoğlu Beşışık   +4 more
doaj   +1 more source