Results 81 to 90 of about 45,806 (246)
Journal of Thrombosis and Haemostasis, 2020 Congenital thrombotic thrombocytopenic purpura (cTTP), otherwise known as Upshaw‐Schulman syndrome, is an extremely rare hereditary disease. Pregnancy is identified as a trigger for TTP episodes in patients with cTTP.
K. Sakai +14 more
semanticscholar +1 more source
Daratumumab for immune thrombotic thrombocytopenic purpura
Blood Advances, 2021 Key Points Treatment of iTTP with daratumumab leads to disappearance of ADAMTS13 inhibitor and restoration of normal ADAMTS13 activity. Targeting of plasma cells with daratumumab is a new treatment option in relapsing and refractory iTTP.
J. van den Berg +6 more
semanticscholar +1 more source
Rare Presentation of Refractory Thrombotic Thrombocytopenic Purpura: Jejunal Stricture
International Journal of Hematology-Oncology and Stem Cell Research, 2017 Thrombotic thrombocytopenic purpura is a rare thrombotic disease characterized by episodes of thrombocytopenia and microangiopathic hemolytic anemia due to disseminated microvascular thrombosis.
Prabath K. Abeysundara +5 more
doaj
FIGO guideline on liver disease and pregnancy
International Journal of Gynecology &Obstetrics, Volume 170, Issue 1, Page 28-48, July 2025.Abstract The number of women entering pregnancy with chronic liver disease is rising. Gestational liver disorders affect 3% of the pregnant population. Both can be associated with significant maternal and fetal morbidity and mortality. European guidance has recently been published to inform management.
Melanie Nana +24 more
wiley +1 more source
Journal of Thrombosis and Haemostasis, 2020 Immune thrombotic thrombocytopenic purpura (iTTP) is a life‐threatening blood disorder, primarily resulting from autoantibodies against ADAMTS13. Infection or inflammation often precedes acute iTTP.
Jingrui Sui +6 more
semanticscholar +1 more source
Clinical Physiology and Functional Imaging, Volume 45, Issue 4, July 2025.Abstract Introduction It remains to be established whether it provides any clinical or diagnostic benefits to perform ventilation/perfusion (V/Q) scintigraphy as a single photon emission computed tomography in children. Here, we report our experience with this modality, evaluate its impact on clinical decision‐making and assess its interrater agreement.
Lise Borgwardt +6 more
wiley +1 more source
Thrombotic microangiopathy and associated renal disorders [PDF]
, 2012 Thrombotic microangiopathy (TMA) is a pathological process involving thrombocytopenia, microangiopathic haemolytic anaemia and microvascular occlusion.
Barbour, T +3 more
core +1 more source
Applied Research, Volume 4, Issue 3, June 2025.The development of a nanobody for Nogo‐A, a potent neurite outgrowth inhibitor crucial in multiple sclerosis, is reported using a rational design approach. The nanobody targets the Nogo‐A ectodomain at the S1PR2 receptor‐binding region with submicromolar KD.
Vaidehi Roy Chowdhury +9 more
wiley +1 more source
Blood, 2018 Preemptive rituximab infusions prevent relapses in immune thrombotic thrombocytopenic purpura (iTTP) by maintaining normal ADAMTS13 activity. However, the long-term outcome of these patients and the potential adverse events of this strategy need to be ...
M. Jestin +26 more
semanticscholar +1 more source
A rare case of hereditary thrombotic thrombocytopenic purpura in a toddler
Liječnički vjesnik, 2023 Hereditary thrombotic thrombocytopenic purpura (hTTP) is a thrombotic microangiopathy caused by pathogenic variants in the ADAMTS13 gene resulting in highly reduced activity of von Willebrand factor-cleaving metalloprotease.
Ozana Jakšić +2 more
doaj +1 more source