Results 11 to 20 of about 206,651 (343)

Thrombotic Thrombocytopenic Purpura: Pathophysiology, Diagnosis, and Management

open access: yesJournal of Clinical Medicine, 2021
Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and ischemic end organ injury due to microvascular platelet-rich thrombi.
S. Sukumar, B. Lämmle, S. Cataland
semanticscholar   +1 more source

Immune Thrombocytopenic Purpura in a Patient with Covid-19

open access: yesNew England Journal of Medicine, 2020
Immune Thrombocytopenic Purpura and Covid-19 Immune thrombocytopenia with lower-extremity purpura, mucosal bleeding, and cerebral microhemorrhage developed during the clinical course in a 65-year-o...
A. Zulfiqar   +3 more
semanticscholar   +1 more source

ISTH guidelines for treatment of thrombotic thrombocytopenic purpura

open access: yesJournal of Thrombosis and Haemostasis, 2020
Despite advances in treatment options for thrombotic thrombocytopenic purpura (TTP), there are still limited high quality data to inform clinicians regarding its appropriate treatment.
X. L. Zheng   +13 more
semanticscholar   +1 more source

ISTH guidelines for the diagnosis of thrombotic thrombocytopenic purpura

open access: yesJournal of Thrombosis and Haemostasis, 2020
Despite an increase in our understandings of pathogenesis of thrombotic thrombocytopenic purpura (TTP), the approaches for initial diagnosis and management of TTP vary significantly.
X. L. Zheng   +13 more
semanticscholar   +1 more source

Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura

open access: yesNew England Journal of Medicine, 2019
BACKGROUND In acquired thrombotic thrombocytopenic purpura (TTP), an immune‐mediated deficiency of the von Willebrand factor–cleaving protease ADAMTS13 allows unrestrained adhesion of von Willebrand factor multimers to platelets and microthrombosis ...
M. Scully   +12 more
semanticscholar   +1 more source

Post-Varicella Purpura Fulminans With Extensive Skin Necrosis in a Child. [PDF]

open access: yesEJHaem
eJHaem, Volume 7, Issue 1, February 2026.
Correia Pires M   +5 more
europepmc   +2 more sources

The differing pathophysiologies that underlie COVID‐19‐associated perniosis and thrombotic retiform purpura: a case series

open access: yesBritish Journal of Dermatology, 2020
There are two distinctive acral manifestations of COVID‐19 embodying disparate clinical phenotypes. One is perniosis occurring in mildly symptomatic patients, typically children and young adults; the second is the thrombotic retiform purpura of ...
C. Magro   +7 more
semanticscholar   +1 more source

“Ghost tablet” husks excreted in feces in large bupropion XL overdose [PDF]

open access: yes, 2018
Background: Extended-release medications are widely prescribed across the spectrum of medical specialties; however, there is heterogeneity in how they are formulated.
Nanagas, Kristine   +2 more
core   +1 more source

Acute cerebellar knockdown of Sgce reproduces salient features of myoclonus-dystonia (DYT11) in mice

open access: yeseLife, 2019
Myoclonus dystonia (DYT11) is a movement disorder caused by loss-of-function mutations in SGCE and characterized by involuntary jerking and dystonia that frequently improve after drinking alcohol.
Samantha Washburn   +4 more
doaj   +1 more source

How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome [PDF]

open access: yes, 2014
Thrombotic thrombocytopenic purpura (TTP) and atypical haemolytic uraemic syndrome (aHUS) are acute, rare life-threatening thrombotic microangiopathies that require rapid diagnosis and treatment.
Goodship, T, Scully, M
core   +1 more source

Home - About - Disclaimer - Privacy