AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Acute cerebellar knockdown of Sgce reproduces salient features of myoclonus-dystonia (DYT11) in mice
eLife, 2019 Myoclonus dystonia (DYT11) is a movement disorder caused by loss-of-function mutations in SGCE and characterized by involuntary jerking and dystonia that frequently improve after drinking alcohol.
Samantha Washburn +4 more
doaj +1 more source
STAR Protocols, 2023 Summary: Presynaptic boutons in the mammalian brain are typically small and difficult to manipulate and study. Here, we present a protocol applying HaloTag self-labeling technology to detect de novo local protein synthesis in intact presynaptic mossy ...
Shivani C. Kharod +3 more
doaj +1 more source
“Ghost tablet” husks excreted in feces in large bupropion XL overdose [PDF]
, 2018 Background: Extended-release medications are widely prescribed across the spectrum of medical specialties; however, there is heterogeneity in how they are formulated.
Nanagas, Kristine +2 more
core +1 more source
Alteration of transcriptomic networks in adoptive-transfer experimental autoimmune encephalomyelitis
Frontiers in Integrative Neuroscience, 2007 Adoptive transfer experimental autoimmune encephalomyelitis (AT-EAE) is an inflammatory demyelination that recapitulates in mouse spinal cord (SC) the human multiple sclerosis disease.
Dumitru A Iacobas +4 more
doaj +1 more source
İmmunoglobulin A Vasküliti Referans Merkez Deneyimi: MEFV Gen Mutasyonunun Klinik Spektruma Etkisi
Sakarya Tıp Dergisi, 2021 İmmunglobulin A vasküliti küçük damarlarda immun kompleks birikimi ile oluşan ve genellikle kendini sınırlayarak iyi seyir gösteren çocukluk çağının en sık vaskülittir.
Nimet Öner +11 more
doaj +1 more source
Clinical surveillance of thrombotic microangiopathies in Scotland, 2003-2005 [PDF]
, 2007 The prevalence, incidence and outcomes of haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are not well established in adults or children from prospective studies. We sought to identify both outcomes and current management
D. YOUNG +8 more
core +2 more sources
How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome [PDF]
, 2014 Thrombotic thrombocytopenic purpura (TTP) and atypical haemolytic uraemic syndrome (aHUS) are acute, rare life-threatening thrombotic microangiopathies that require rapid diagnosis and treatment.
Goodship, T, Scully, M
core +1 more source
A role for cerebellum in the hereditary dystonia DYT1
eLife, 2017 DYT1 is a debilitating movement disorder caused by loss-of-function mutations in torsinA. How these mutations cause dystonia remains unknown. Mouse models which have embryonically targeted torsinA have failed to recapitulate the dystonia seen in patients,
Rachel Fremont +3 more
doaj +1 more source
Pathogenicity of anti-ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura. [PDF]
, 2015 BACKGROUND: Acquired thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease in which anti-ADAMTS13 autoantibodies cause severe enzyme deficiency.
Crawley, JT +3 more
core +2 more sources