Diagnosis and management of immune thrombocytopenic purpura (ITP) remain largely dependent on clinical expertise and observations more than on evidence derived from clinical trials of high scientific quality.
F. Rodeghiero+19 more
semanticscholar +1 more source
Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad+6 more
core +2 more sources
Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]
Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Catlow, Jamie+4 more
core +1 more source
Coordination between Translation and Degradation Regulates Inducibility of mGluR-LTD
Dendritic protein homeostasis is crucial for most forms of long-term synaptic plasticity, and its dysregulation is linked to a wide range of brain disorders.
Matthew E. Klein+2 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana+6 more
wiley +1 more source
A Case of Henoch-Schonlein Purpura Associated with Rotavirus Infection in an Elderly Asian Male and Review of the Literature. [PDF]
BACKGROUND Henoch-Schönlein purpura (HSP), a small vessel vasculitis mediated by deposition of immune-complexes containing IgA in the skin, gut, and glomeruli, often presents with abdominal pain, purpuric rash in the lower extremities and buttocks, joint
Adderley+13 more
core +2 more sources
“Ghost tablet” husks excreted in feces in large bupropion XL overdose [PDF]
Background: Extended-release medications are widely prescribed across the spectrum of medical specialties; however, there is heterogeneity in how they are formulated.
Nanagas, Kristine+2 more
core +1 more source
Acute cerebellar knockdown of Sgce reproduces salient features of myoclonus-dystonia (DYT11) in mice
Myoclonus dystonia (DYT11) is a movement disorder caused by loss-of-function mutations in SGCE and characterized by involuntary jerking and dystonia that frequently improve after drinking alcohol.
Samantha Washburn+4 more
doaj +1 more source
IgA vasculitis associated with renal and joint findings in children and correlation between patient’s compliance in treatment: A case series [PDF]
Objectives. Evaluation and therapeutic management of pediatric patients having Henoch-Schönlein purpura with renal and joint involvement and the importance of their follow-up in preventing complications.
Ana-Maria Roxana Koller, Alexandra Man
doaj +1 more source
Caplacizumab for Acquired Thrombotic Thrombocytopenic Purpura.
BACKGROUND Acquired thrombotic thrombocytopenic purpura (TTP) is caused by aggregation of platelets on ultralarge von Willebrand factor multimers. This microvascular thrombosis causes multiorgan ischemia with potentially life-threatening complications ...
F. Peyvandi+13 more
semanticscholar +1 more source