Results 21 to 30 of about 206,651 (343)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Coordination between Translation and Degradation Regulates Inducibility of mGluR-LTD

open access: yesCell Reports, 2015
Dendritic protein homeostasis is crucial for most forms of long-term synaptic plasticity, and its dysregulation is linked to a wide range of brain disorders.
Matthew E. Klein   +2 more
doaj   +1 more source

Spatial contextual effects in primary visual cortex limit feature representation under crowding

open access: yesNature Communications, 2020
Visual crowding can strongly limit perceptual discriminability, yet its neural basis remains unclear. Here, the authors show that perceptual crowding is similar in monkeys and humans, and that feature encoding in neuronal populations in primary visual ...
Christopher A. Henry, Adam Kohn
doaj   +1 more source

Protocol to study presynaptic protein synthesis in ex vivo mouse hippocampal slices using HaloTag technology

open access: yesSTAR Protocols, 2023
Summary: Presynaptic boutons in the mammalian brain are typically small and difficult to manipulate and study. Here, we present a protocol applying HaloTag self-labeling technology to detect de novo local protein synthesis in intact presynaptic mossy ...
Shivani C. Kharod   +3 more
doaj   +1 more source

Alteration of transcriptomic networks in adoptive-transfer experimental autoimmune encephalomyelitis

open access: yesFrontiers in Integrative Neuroscience, 2007
Adoptive transfer experimental autoimmune encephalomyelitis (AT-EAE) is an inflammatory demyelination that recapitulates in mouse spinal cord (SC) the human multiple sclerosis disease.
Dumitru A Iacobas   +4 more
doaj   +1 more source

Cryoglobulinaemic vasculitis: classification and clinical and therapeutic aspects [PDF]

open access: yes, 2007
Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection.
Braun, Gerald S.   +4 more
core   +2 more sources

A role for cerebellum in the hereditary dystonia DYT1

open access: yeseLife, 2017
DYT1 is a debilitating movement disorder caused by loss-of-function mutations in torsinA. How these mutations cause dystonia remains unknown. Mouse models which have embryonically targeted torsinA have failed to recapitulate the dystonia seen in patients,
Rachel Fremont   +3 more
doaj   +1 more source

Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]

open access: yes, 2014
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad   +6 more
core   +2 more sources

Childhood IgA Vasculitis (Henoch Schonlein Purpura)—Advances and Knowledge Gaps

open access: yesFrontiers in Pediatrics, 2019
Immunoglobulin A vasculitis (IgAV; formerly Henoch Schonlein Purpura) is the most common form of childhood vasculitis. It can occur in any age and peaks around 4–6 years old.
L. Oni, S. Sampath
semanticscholar   +1 more source

Idiopathic Thrombocytopenic Purpura

open access: yesDefinitions, 2020
B-cell disorders include a large group of malignant and nonmalignant diseases with tremendous variation in incidence, natural history, treatment, and prognosis.
Amy Goodrich
semanticscholar   +1 more source

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