Results 11 to 20 of about 56,569 (191)
STAR Protocols, 2023 Summary: Presynaptic boutons in the mammalian brain are typically small and difficult to manipulate and study. Here, we present a protocol applying HaloTag self-labeling technology to detect de novo local protein synthesis in intact presynaptic mossy ...
Shivani C. Kharod +3 more
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Coordination between Translation and Degradation Regulates Inducibility of mGluR-LTD
Cell Reports, 2015 Dendritic protein homeostasis is crucial for most forms of long-term synaptic plasticity, and its dysregulation is linked to a wide range of brain disorders.
Matthew E. Klein +2 more
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A role for cerebellum in the hereditary dystonia DYT1
eLife, 2017 DYT1 is a debilitating movement disorder caused by loss-of-function mutations in torsinA. How these mutations cause dystonia remains unknown. Mouse models which have embryonically targeted torsinA have failed to recapitulate the dystonia seen in patients,
Rachel Fremont +3 more
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Neurobiology of Disease, 2015 Loss-of-function mutations in the α3 isoform of the sodium pump are responsible for Rapid Onset Dystonia–Parkinsonism (RDP). A pharmacologic model of RDP replicates the most salient features of RDP, and implicates both the cerebellum and basal ganglia in
Rachel Fremont +2 more
doaj +1 more source
Natural ITD statistics predict human auditory spatial perception
eLife, 2020 A neural code adapted to the statistical structure of sensory cues may optimize perception. We investigated whether interaural time difference (ITD) statistics inherent in natural acoustic scenes are parameters determining spatial discriminability.
Rodrigo Pavão +3 more
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Viruses, 2021 Extrahepatic manifestations are a feature of chronic hepatitis C virus (HCV) infection. In the course of chronic HCV infection, about 70% of patients have one or more extrahepatic manifestations.
Cesare Mazzaro +9 more
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Henoch–Schonlein purpura due to sodium valproate: A case report
Clinical Case Reports, 2022 We report a 5‐year‐old girl with a generalized seizure treated with sodium valproate syrup. She returned to the clinic with Henoch–Schonlein purpura after 20 days due to the consumption of sodium valproate.
Firozeh Hosseini, Mojgan Safari
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CRYPTOGENIC INCREASED ACTIVITY OF ASPARTATE AMINOTRANSFERASE: A CASE REPORT
Slovenska pediatrija, 2021 We present a case of cryptogenic elevation of aspartate aminotransferase (AST) activity. AST is an enzyme found in many tissues, so the serum activity of this enzyme may be elevated in various diseases.
Tjaša Žagar, Rok Orel
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Sex-specific hypothalamic neural projection activity drives caregiving in mice
Nature CommunicationsInfant care is critical for survival and healthy development. In laboratory mice, unmated males and females display infant-directed behavior ranging from neglect and aggression to alloparental care.
Ilaria Carta +6 more
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