Clinical surveillance of thrombotic microangiopathies in Scotland, 2003-2005 [PDF]
, 2008 The prevalence, incidence and outcomes of haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are not well established in adults or children from prospective studies. We sought to identify both outcomes and current management
Todd, W.T.A. +3 more
core +4 more sources
Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]
, 2010 Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Douglas, Kenneth W. +4 more
core +4 more sources
Human protein C concentrate in the treatment of purpura fulminans : a retrospective analysis of safety and outcome in 94 pediatric patients [PDF]
, 2010 Introduction: Purpura fulminans (PF) is a devastating complication of uncontrolled systemic inflammation, associated with high incidence of amputations, skin grafts and death.
Doris Fischer +16 more
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A role for cerebellum in the hereditary dystonia DYT1
eLife, 2017 DYT1 is a debilitating movement disorder caused by loss-of-function mutations in torsinA. How these mutations cause dystonia remains unknown. Mouse models which have embryonically targeted torsinA have failed to recapitulate the dystonia seen in patients,
Rachel Fremont +3 more
doaj +1 more source
IgA vasculitis associated with renal and joint findings in children and correlation between patient’s compliance in treatment: A case series [PDF]
Romanian Journal of Pediatrics, 2023 Objectives. Evaluation and therapeutic management of pediatric patients having Henoch-Schönlein purpura with renal and joint involvement and the importance of their follow-up in preventing complications.
Ana-Maria Roxana Koller, Alexandra Man
doaj +1 more source
Thrombotic Thrombocytopenic Purpura, Moschcowitz Syndrome [PDF]
, 2001 The authors present a case of a 16-year-old boy, who was referred to the hospital due to thrombocytopenia, anemia, proteinuria and hyperbilirubinemia. Based on the clinical picture and the laboratory data, thrombotic thrombocytopenic purpura (TTP) was ...
Czinyéri, Judit +4 more
core +1 more source
Coordination between Translation and Degradation Regulates Inducibility of mGluR-LTD
Cell Reports, 2015 Dendritic protein homeostasis is crucial for most forms of long-term synaptic plasticity, and its dysregulation is linked to a wide range of brain disorders.
Matthew E. Klein +2 more
doaj +1 more source
Neurobiology of Disease, 2015 Loss-of-function mutations in the α3 isoform of the sodium pump are responsible for Rapid Onset Dystonia–Parkinsonism (RDP). A pharmacologic model of RDP replicates the most salient features of RDP, and implicates both the cerebellum and basal ganglia in
Rachel Fremont +2 more
doaj +1 more source
Journal of the American Medical Association, 1909 In the following case I have regarded the condition as a distinct malady for descriptive purposes, since hemorrhages were the dominating feature. Symptoms of slight fever and weakness seemed not causative, but natural results respectively of ferment in the ecchymoses and loss of blood. Family History. —The patient's family consisted of father, mother
openaire +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source