A Retrospective Observational Single-Centre Study on the Burden of Immune Thrombocytopenia (ITP) [PDF]
Background: German data on economic consequences of immune thrombocytopenia (ITP) are limited. Patients and Methods: A retrospective, observational study based on chart review of adult patients with a confirmed diagnosis of ITP was conducted at a German ...
Ackermann, Birgit+6 more
core +1 more source
Alteration of transcriptomic networks in adoptive-transfer experimental autoimmune encephalomyelitis
Adoptive transfer experimental autoimmune encephalomyelitis (AT-EAE) is an inflammatory demyelination that recapitulates in mouse spinal cord (SC) the human multiple sclerosis disease.
Dumitru A Iacobas+4 more
doaj +1 more source
Childhood IgA Vasculitis (Henoch Schonlein Purpura)—Advances and Knowledge Gaps
Immunoglobulin A vasculitis (IgAV; formerly Henoch Schonlein Purpura) is the most common form of childhood vasculitis. It can occur in any age and peaks around 4–6 years old.
L. Oni, S. Sampath
semanticscholar +1 more source
Measuring spike train synchrony [PDF]
Estimating the degree of synchrony or reliability between two or more spike trains is a frequent task in both experimental and computational neuroscience.
Abarbanel, Henry D. I.+4 more
core +3 more sources
A role for cerebellum in the hereditary dystonia DYT1
DYT1 is a debilitating movement disorder caused by loss-of-function mutations in torsinA. How these mutations cause dystonia remains unknown. Mouse models which have embryonically targeted torsinA have failed to recapitulate the dystonia seen in patients,
Rachel Fremont+3 more
doaj +1 more source
Pathogenicity of anti-ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura. [PDF]
BACKGROUND: Acquired thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease in which anti-ADAMTS13 autoantibodies cause severe enzyme deficiency.
Crawley, JT+3 more
core +2 more sources
Hereditary thrombotic thrombocytopenic purpura
The first description of thrombotic thrombocytopenic purpura (TTP) by Moschowitz was published nearly 100 years ago.[1][1] This was likely to have been an immune-mediated TTP episode and the author described multi organs affected with worsening ...
M. Scully
semanticscholar +2 more sources
Henoch–Schonlein purpura due to sodium valproate: A case report
We report a 5‐year‐old girl with a generalized seizure treated with sodium valproate syrup. She returned to the clinic with Henoch–Schonlein purpura after 20 days due to the consumption of sodium valproate.
Firozeh Hosseini, Mojgan Safari
doaj +1 more source
Characterization and treatment of congenital thrombotic thrombocytopenic purpura.
Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra-rare thrombomicroangiopathy caused by an inherited deficiency of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13).
F. Alwan+27 more
semanticscholar +1 more source
Characterization of the complications associated with plasma exchange for thrombotic thrombocytopaenic purpura and related thrombotic microangiopathic anaemias: a single institution experience. [PDF]
Plasma exchange (PEX) is a life-saving therapeutic procedure in patients with thrombotic thrombocytopaenic purpura (TTP) and other thrombotic microangiopathic anaemias (TMAs). However, it may be associated with significant complications, exacerbating the
Collier, D+5 more
core +2 more sources