Results 41 to 50 of about 206,651 (343)

Characterization and treatment of congenital thrombotic thrombocytopenic purpura.

Blood, 2019
Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra-rare thrombomicroangiopathy caused by an inherited deficiency of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13).
F. Alwan, C. Vendramin, R. Liesner, A. Clark, W. Lester, T. Dutt, W. Thomas, R. Gooding, T. Biss, Henry G. Watson, N. Cooper, R. Rayment, T. Cranfield, J. J. Veen, Q. Hill, Sarah Davis, J. Motwani, N. Bhatnagar, Nicole Priddee, M. Dávid, Maeve P. Crowley, J. Alamelu, H. Lyall, J. Westwood, M. Thomas, M. Thomas, M. Scully, M. Scully   +27 more
semanticscholar   +1 more source

Henoch–Schonlein purpura due to sodium valproate: A case report

Clinical Case Reports, 2022
We report a 5‐year‐old girl with a generalized seizure treated with sodium valproate syrup. She returned to the clinic with Henoch–Schonlein purpura after 20 days due to the consumption of sodium valproate.
Firozeh Hosseini, Mojgan Safari
doaj   +1 more source

Clinical surveillance of thrombotic microangiopathies in Scotland, 2003-2005 [PDF]

, 2007
The prevalence, incidence and outcomes of haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are not well established in adults or children from prospective studies. We sought to identify both outcomes and current management
D. YOUNG, Hosler, K. G. J. POLLOCK, Marques, Sadler, T. J. BEATTIE, Tarr, Van Dyck, W. T. A. TODD   +8 more
core   +2 more sources

Pneumococcal purpura fulminans in asplenic or hyposplenic patients: a French multicenter exposed-unexposed retrospective cohort study

Critical Care, 2020
Background Pneumococcal infections remain the main cause of overwhelming post-splenectomy infections, and purpura fulminans may develop in almost 20% of patients with overwhelming post-splenectomy infection.
D. Contou, R. Coudroy, G. Colin, J. Tadié, M. Cour, R. Sonneville, A. Mekontso Dessap, N. de Prost, Laurent François Amélie Gaëtan Frédéric Pascal Pascal Cédr Argaud Barbier Bazire Béduneau Bellec Beuret Blanc, L. Argaud, F. Barbier, A. Bazire, G. Béduneau, F. Bellec, P. Beuret, P. Blanc, C. Bruel, C. Brun-Buisson, G. Colin, Delphine Colling, A. Conia, R. Coudroy, M. Cour, D. Contou, F. Daviaud, V. Das, J. Dellamonica, Nadège Demars, S. Ehrmann, A. Galbois, E. Gélisse, J. Grouille, L. Guérin, E. Guérot, S. Jaber, Caroline Jannière, S. Jochmans, M. Jozwiak, P. Kalfon, A. Kimmoun, A. Lautrette, J. Lemarié, C. Le Moal, C. Lenclud, N. Lerolle, O. Leroy, A. Marchalot, B. Mégarbane, A. Dessap, E. de Montmollin, F. Pène, C. Pichereau, G. Plantefeve, S. Préau, G. Preda, N. de Prost, J. Quenot, S. Ricôme, D. Roux, B. Sauneuf, M. Schmidt, G. Schnell, R. Sonneville, J. Tadié, Yacine Tandjaoui, M. Tchir, N. Terzi, X. Valette, L. Zafrani, B. Zuber   +69 more
semanticscholar   +1 more source

CRYPTOGENIC INCREASED ACTIVITY OF ASPARTATE AMINOTRANSFERASE: A CASE REPORT

Slovenska pediatrija, 2021
We present a case of cryptogenic elevation of aspartate aminotransferase (AST) activity. AST is an enzyme found in many tissues, so the serum activity of this enzyme may be elevated in various diseases.
Tjaša Žagar, Rok Orel
doaj   +1 more source

Which spike train distance is most suitable for distinguishing rate and temporal coding?

, 2018
Background: It is commonly assumed in neuronal coding that repeated presentations of a stimulus to a coding neuron elicit similar responses. One common way to assess similarity are spike train distances.
Kreuz, Thomas, Satuvuori, Eero
core   +3 more sources

Tapering thrombopoietin receptor agonists in primary immune thrombocytopenia: Expert consensus based on the RAND/UCLA modified Delphi panel method

Research and Practice in Thrombosis and Haemostasis, 2021
Background Thrombopoietin receptor agonists (TPO‐RAs) are used to treat primary immune thrombocytopenia (ITP). Some patients have discontinued treatment while maintaining a hemostatic platelet count.
Adam Cuker, Jenny M. Despotovic, Rachael F. Grace, Caroline Kruse, Michele P. Lambert, Howard A. Liebman, Roger M. Lyons, Keith R. McCrae, Vinod Pullarkat, Jeffrey S. Wasser, David Beenhouwer, Sarah N. Gibbs, Irina Yermilov, Michael S. Broder   +13 more
doaj   +1 more source

Discussion required for correct interpretation [PDF]

, 2006
Thank you for the opportunity to comment on the editorial by Romero and colleagues [1], which raises a number of important and interesting questions.
Aguan, Bethin, Challis, Chan, Gary D. V Hankins, George R Saade, Radek Bukowski, Romero, Slater, Sparey, Steve Thornton   +10 more
core   +3 more sources

Sex-specific hypothalamic neural projection activity drives caregiving in mice

Nature Communications
Infant care is critical for survival and healthy development. In laboratory mice, unmated males and females display infant-directed behavior ranging from neglect and aggression to alloparental care.
Ilaria Carta, Tushar Arora, Stefano Lutzu, Giovanni Podda, Gaspar Nicolay Vera Ortega, Stephanie Rudolph, Anita E. Autry   +6 more
doaj   +1 more source

Aberrant cerebellar Purkinje cell activity as the cause of motor attacks in a mouse model of episodic ataxia type 2

Disease Models & Mechanisms, 2018
Many cerebellar-induced neurological disorders, such as ataxias and cerebellar-induced dystonias, are associated with abnormal Purkinje cell activity. In tottering mice, a well-established mouse model of episodic ataxia type 2 (EA2), cerebellar Purkinje ...
Esra Tara, Ariel Vitenzon, Ellen Hess, Kamran Khodakhah   +3 more
doaj   +1 more source