Results 31 to 40 of about 4,220 (193)

Pediatric Sepsis: clinical Considerations [PDF]

open access: yes, 2018
L
Balázs, Gergely   +3 more
core   +1 more source

Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel

open access: yesEmerging Infectious Diseases, 2018
We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case ...
Regev Cohen   +6 more
doaj   +1 more source

Infectious purpura fulminans

open access: yesIndian Journal of Medical Research, 2015
A 60 year old male patient was admitted to the medical intensive care unit (MICU) at the Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, in October 2013, with acute exacerbation of chronic obstructive pulmonary disease, acute respiratory failure requiring mechanical ventilatory support.
J, Harikrishna, Alladi, Mohan
openaire   +2 more sources

Successful Treatment of Severe Purpura Fulminans With Anakinra

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Purpura fulminans (PF) is a rare, often fatal pediatric condition characterized by intravascular thrombosis and hemorrhagic infarction of the skin. A timely diagnosis and treatment are paramount to prevent the involvement of internal organs, causing disseminated intravascular coagulation and gangrene of the extremities.
Francesco Zulian   +4 more
wiley   +1 more source

The use of negative-pressure wound therapy over a cultured epithelial autograft for full-thickness wounds secondary to purpura fulminans in an infant

open access: yesArchives of Plastic Surgery, 2021
Purpura fulminans is a serious condition that can result in severe morbidity in the pediatric population. Although autologous skin grafts remain the gold standard for the coverage of partial- to full-thickness wounds, they have several limitations in ...
Benjamin Kah Liang Goh   +6 more
doaj   +1 more source

Protein C Replacement in Severe Meningococcemia: Rationale and Clinical Experience [PDF]

open access: yes, 2017
Severe meningococcemia, which is associated with hemodynamic instability, purpura fulminans and disseminated intravascular coagulation, still has a high mortality rate, and patients who survive are often left invalids because of amputations and organ ...
Alberio, Lorenzo   +2 more
core  

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami   +2 more
wiley   +1 more source

Intrauterine purpura fulminans

open access: yesThe Turkish Journal of Pediatrics, 1975
S Ozsoylu, S Bektaş
doaj   +2 more sources

Invasive Meningococcal Disease in a Patient With Complement 7 Deficiency

open access: yesJournal of General and Family Medicine, Volume 26, Issue 6, Page 646-649, November 2025.
ABSTRACT Neisseria meningitidis can cause invasive meningococcal disease (IMD). Individuals with primary complement deficiencies are at a higher risk of developing IMD. However, cases of IMD associated with complement deficiency have rarely been reported in Japan.
Hiroaki Nishioka   +2 more
wiley   +1 more source

Disseminated Intravascular Coagulation with Purpura Fulminans Presentation of Acute Promyelocytic Leukemia [PDF]

open access: yes, 2019
A 47-year-old male presented to the emergency department with 12 hours of nausea, vomiting, abdominal pain, and a widespread skin eruption with mottled, irregular, purpuric lesions with subsequent rapid decompensation.
Ader, Douglas   +2 more
core  

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