Results 41 to 50 of about 2,039 (167)

Infectious purpura fulminans

Indian Journal of Medical Research, 2015
A 60 year old male patient was admitted to the medical intensive care unit (MICU) at the Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, in October 2013, with acute exacerbation of chronic obstructive pulmonary disease, acute respiratory failure requiring mechanical ventilatory support.
J, Harikrishna, Alladi, Mohan
openaire   +2 more sources

A Retrospective Study of Adult and Pediatric D‐Dimer Tests to Identify Opportunities for Improved Utilization

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 392-401, April 2026.
ABSTRACT Introduction D‐dimers are produced by lysis of cross‐linked fibrin. In children, D‐dimer testing is used to evaluate disseminated intravascular coagulation (DIC) and some inflammatory states, but its use is not validated for screening or ruling out suspected venous thromboembolic events (VTE).
Rabab Al Dawood, Hassan Abu Sabah, Natalie Mathews, James Douketis, Catherine Hayward   +4 more
wiley   +1 more source

Rare presentation of rickettsial infection as purpura fulminans: a case report

Journal of Medical Case Reports, 2018
Background Purpura fulminans is an acute life-threatening disorder characterized by intravascular thrombosis and hemorrhagic infarction of the skin complicated with disseminated intravascular coagulation. It is commonly seen in acute infections following
Chamara Dalugama, Indika Bandara Gawarammana   +1 more
doaj   +1 more source

Fatal meningococcal septicemia without meningeal signs, contribution of the peripheral smear in diagnosis: Report of a case

Indian Journal of Pathology and Microbiology, 2018
Acute meningococcemia is characterized by extensive purpurae consisting of both petechiae and ecchymoses. This condition can be rapidly fatal without treatment due to shock and severe consumptive coagulopathy.
Deepti Mutreja, Nikhil Moorchung, S J Manasa, Jeenu Varghese   +3 more
doaj   +1 more source

Neisseria meningitidis Induced Fatal Waterhouse–Friderichsen Syndrome in a Patient Presenting With Disseminated Intravascular Coagulation and Multiple Organ Failure

Brain Sciences, 2020
Neisseria meningitidis-induced acute systemic meningococcal disease is an emergency and a fatal condition that has a high mortality rate. In patients with a fulminant infection, a maculopapular petechial eruption, purpura fulminans, or an ecchymotic ...
Meng-Yu Wu, Chien-Sheng Chen, Chih-Yi Tsay, Giou-Teng Yiang, Jian-Yu Ke, Po-Chen Lin   +5 more
doaj   +1 more source

Capnocytophaga canimorsus Septicaemia Presenting With Multiorgan Dysfunction Syndrome (MODS) and Disseminated Intravascular Coagulation (DIC) in an Immunocompetent Individual

Case Reports in Critical Care, Volume 2026, Issue 1, 2026.
We present a rare case of fulminant Capnocytophaga canimorsus septicaemia in a previously well 52‐year‐old immunocompetent woman, following a minor dog‐related forehead abrasion. Despite a recent course of amoxicillin/clavulanate prescribed by her general practitioner, the patient developed profound sepsis characterised by disseminated intravascular ...
Kadison Michel, Prashant Pruthi, Charlie Corke, Lipi Buch   +3 more
wiley   +1 more source

Use of Double Dose Intravenous Immunoglobulin Therapy in the Treatment of Streptococcal Toxic Shock Syndrome

Case Reports in Critical Care, Volume 2026, Issue 1, 2026.
Streptococcal toxic shock syndrome (STSS) is a life‐threatening condition with increasing incidence and high mortality worldwide. It is characterised by hypotension and multiorgan failure, resultant of invasive group A Streptococcus (GAS) infections. Intravenous immunoglobulin (IVIG) has been proposed as an adjunctive therapy that reduces mortality in ...
Yuning Xue, Alex Yartsev, Lipi Buch
wiley   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Invasive Meningococcal Disease in a Patient With Complement 7 Deficiency

Journal of General and Family Medicine, Volume 26, Issue 6, Page 646-649, November 2025.
ABSTRACT Neisseria meningitidis can cause invasive meningococcal disease (IMD). Individuals with primary complement deficiencies are at a higher risk of developing IMD. However, cases of IMD associated with complement deficiency have rarely been reported in Japan.
Hiroaki Nishioka, Kazuki Maegawa, Shigeo Hara   +2 more
wiley   +1 more source

Necrotizing Fasciitis of Eyelid in Children: A Rare Complication of Varicella Infection

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Necrotizing fasciitis (NF) of the eyelid is an extremely rare but severe complication of varicella zoster virus (VZV) infection in children. We present a case of an 8‐year‐old girl who developed necrotizing fasciitis of the left eyelid following varicella infection.
Govinda Bhandari, Himal Acharya, Richa Paudyal   +2 more
wiley   +1 more source