Results 31 to 40 of about 2,039 (167)

PURPURA FULMINANS. [PDF]

The Lancet, 1912
n ...
openaire   +2 more sources

Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel

Emerging Infectious Diseases, 2018
We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case ...
Regev Cohen, Frida Babushkin, Maurice Shapiro, Martina Uda, Yafit Atiya-Nasagi, Dar Klein, Talya Finn   +6 more
doaj   +1 more source

Clinically Suspected Invasive Meningococcal Disease Presenting With Purpura Fulminans‐Like Rash, Septic Shock, Multiorgan Dysfunction, and Recovery From ARDS in a Previously Healthy Child

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Clinically suspected invasive meningococcal disease can deteriorate rapidly in previously well children. Prompt recognition of the petechial–purpuric rash with shock, early empirical antibiotics, and aggressive supportive pediatric intensive care are cornerstones of management as multiorgan dysfunction and Acute Respiratory Distress Syndrome ...
Shatha Omar, Adil Alsweis, Amr Khaled, Noor Nabresi, Mosub Qatu, Yahya Qahwash, Mahfouth Jallad   +6 more
wiley   +1 more source

Prenatal Etiology Diagnosis of Rare Compound Heterozygous PROC Gene Variants in a Fetus With Ocular Ultrasonic Anomaly Using Whole Exome Sequencing

Molecular Genetics &Genomic Medicine, Volume 14, Issue 7, July 2026.
This study first describes two rare compound heterozygous variants in PROC gene in a Chinese individual, which may broaden the mutation spectrum of thrombophilia due to protein C deficiency. ABSTRACT Background This study aims to present novel compound heterozygous PROC gene variants in a fetus.
Jianlong Zhuang, Nan Huang, Ling Gu, Wanyu Fu   +3 more
wiley   +1 more source

Advancing tele‐physiology: A chest patch solution for continuous, non‐invasive remote monitoring in a hypoxic environment

Experimental Physiology, Volume 111, Issue 7, Page 3280-3293, 1 July 2026.
Abstract Skin‐mounted sensors are thin, flexible and lightweight electronic devices that enable monitoring of multiple physiological parameters. The aim of this study was to provide pilot evidence for possible utilization of a sensorized patch for capturing the bodily response to hypoxia. The subsequent phases of the study comprised a case report and a
Danilo Bondi, Ferdinando Calcagno, Elisa Fioraso, Camillo Di Giulio, Federico Schena, Anna Pedrinolla   +5 more
wiley   +1 more source

Neonatal Wet Gangrene With Early Auto‐Amputation in a Resource‐Limited Setting With Incomplete Etiologic Workup: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Neonatal limb gangrene with auto‐amputation is rare and often idiopathic. Early recognition, prompt referral, and thorough etiologic workup—despite resource limitations—are critical. Wet gangrene requires broad‐spectrum antibiotics, wound care, and timely surgical amputation to preserve growth plates and allow future prosthesis fitting.
Milki Tufa Feyisa, Beza Eshetu, Tolosa Dibisa, Mulatu Gshaw, Birhanu Tolera, Endalew Dessie Birara, Adugna Lamessa, Tamirat Godebo Woyimo   +7 more
wiley   +1 more source

An Uncommon Case of Ecthyma Gangrenosum in a Three‐Year‐Old Immunocompetent Child

Clinical Case Reports, Volume 14, Issue 6, June 2026.
The necrotic lesions on day 10. ABSTRACT Ecthyma gangrenosum (EG) is a rare cutaneous finding of Pseudomonas aeruginosa sepsis, typically in immunocompromised patients. We present EG with septic shock in a previously healthy three‐year‐old child who presented with rapidly progressing necrotic eschars and severe neutropenia.
Shobha Maharjan, Nipun Shrestha, Dhruba Shrestha   +2 more
wiley   +1 more source

Analysis of the Phenotype and Gene Mutations of Two Families With Combined Mutations of Anticoagulant Protein Genes

Molecular Genetics &Genomic Medicine, Volume 14, Issue 4, April 2026.
In these two pedigrees, we identified distinct mutations in the AT and PC genes. Individuals harboring both mutations exhibited a significantly higher incidence of venous thrombosis. ABSTRACT Background AT and PC are key components of the anticoagulant system. Mutations in their encoding genes, SERPINC1 and PROC, can lead to insufficient protein levels
Yueli Guo, Tingting Shan, Wenjieying Zheng, Chun Zhao, Wanzhong Kong, Xiaojing Zou   +5 more
wiley   +1 more source

Protein C Deficiency Caused by a Novel Mutation in the PROC Gene in an Infant with Delayed Onset Purpura Fulminans

Case Reports in Dermatological Medicine, 2017
Protein C is an anticoagulant that is encoded by the PROC gene. Protein C deficiency (PCD) is inherited in an autosomal dominant or recessive pattern.
Mariam S. Al Harbi, Ayman W. El-Hattab
doaj   +1 more source

The use of negative-pressure wound therapy over a cultured epithelial autograft for full-thickness wounds secondary to purpura fulminans in an infant

Archives of Plastic Surgery, 2021
Purpura fulminans is a serious condition that can result in severe morbidity in the pediatric population. Although autologous skin grafts remain the gold standard for the coverage of partial- to full-thickness wounds, they have several limitations in ...
Benjamin Kah Liang Goh, Alvin Wen Choong Chua, Khong Yik Chew, Gavin Chun-Wui Kang, Li-Wei Chiang, Bien-Keem Tan, Savitha Ramachandran   +6 more
doaj   +1 more source