Results 51 to 60 of about 21,807 (192)

Infectious purpura fulminans

open access: yesIndian Journal of Medical Research, 2015
A 60 year old male patient was admitted to the medical intensive care unit (MICU) at the Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, in October 2013, with acute exacerbation of chronic obstructive pulmonary disease, acute respiratory failure requiring mechanical ventilatory support.
J, Harikrishna, Alladi, Mohan
openaire   +2 more sources

An Uncommon Case of Ecthyma Gangrenosum in a Three‐Year‐Old Immunocompetent Child

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
The necrotic lesions on day 10. ABSTRACT Ecthyma gangrenosum (EG) is a rare cutaneous finding of Pseudomonas aeruginosa sepsis, typically in immunocompromised patients. We present EG with septic shock in a previously healthy three‐year‐old child who presented with rapidly progressing necrotic eschars and severe neutropenia.
Shobha Maharjan   +2 more
wiley   +1 more source

Analysis of the Phenotype and Gene Mutations of Two Families With Combined Mutations of Anticoagulant Protein Genes

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 4, April 2026.
In these two pedigrees, we identified distinct mutations in the AT and PC genes. Individuals harboring both mutations exhibited a significantly higher incidence of venous thrombosis. ABSTRACT Background AT and PC are key components of the anticoagulant system. Mutations in their encoding genes, SERPINC1 and PROC, can lead to insufficient protein levels
Yueli Guo   +5 more
wiley   +1 more source

A Retrospective Study of Adult and Pediatric D‐Dimer Tests to Identify Opportunities for Improved Utilization

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 2, Page 392-401, April 2026.
ABSTRACT Introduction D‐dimers are produced by lysis of cross‐linked fibrin. In children, D‐dimer testing is used to evaluate disseminated intravascular coagulation (DIC) and some inflammatory states, but its use is not validated for screening or ruling out suspected venous thromboembolic events (VTE).
Rabab Al Dawood   +4 more
wiley   +1 more source

Protein C Deficiency Caused by a Novel Mutation in the PROC Gene in an Infant with Delayed Onset Purpura Fulminans

open access: yesCase Reports in Dermatological Medicine, 2017
Protein C is an anticoagulant that is encoded by the PROC gene. Protein C deficiency (PCD) is inherited in an autosomal dominant or recessive pattern.
Mariam S. Al Harbi, Ayman W. El-Hattab
doaj   +1 more source

The use of negative-pressure wound therapy over a cultured epithelial autograft for full-thickness wounds secondary to purpura fulminans in an infant

open access: yesArchives of Plastic Surgery, 2021
Purpura fulminans is a serious condition that can result in severe morbidity in the pediatric population. Although autologous skin grafts remain the gold standard for the coverage of partial- to full-thickness wounds, they have several limitations in ...
Benjamin Kah Liang Goh   +6 more
doaj   +1 more source

Rare presentation of rickettsial infection as purpura fulminans: a case report

open access: yesJournal of Medical Case Reports, 2018
Background Purpura fulminans is an acute life-threatening disorder characterized by intravascular thrombosis and hemorrhagic infarction of the skin complicated with disseminated intravascular coagulation. It is commonly seen in acute infections following
Chamara Dalugama   +1 more
doaj   +1 more source

Fatal meningococcal septicemia without meningeal signs, contribution of the peripheral smear in diagnosis: Report of a case

open access: yesIndian Journal of Pathology and Microbiology, 2018
Acute meningococcemia is characterized by extensive purpurae consisting of both petechiae and ecchymoses. This condition can be rapidly fatal without treatment due to shock and severe consumptive coagulopathy.
Deepti Mutreja   +3 more
doaj   +1 more source

Neisseria meningitidis Induced Fatal Waterhouse–Friderichsen Syndrome in a Patient Presenting With Disseminated Intravascular Coagulation and Multiple Organ Failure

open access: yesBrain Sciences, 2020
Neisseria meningitidis-induced acute systemic meningococcal disease is an emergency and a fatal condition that has a high mortality rate. In patients with a fulminant infection, a maculopapular petechial eruption, purpura fulminans, or an ecchymotic ...
Meng-Yu Wu   +5 more
doaj   +1 more source

Efficacy and Safety of Human Protein C Concentrate in Japanese Patients With Severe Congenital Protein C Deficiency

open access: yesPediatrics International, Volume 68, Issue 1, January/December 2026.
ABSTRACT Background Severe congenital protein C deficiency (SCPCD) is a rare disorder associated with life‐threatening thrombotic complications. Protein C concentrate is recommended for both acute and long‐term management of SCPCD. However, no efficacy and safety data in Japanese patients have been reported.
Katsuyoshi Koh   +8 more
wiley   +1 more source

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