Results 61 to 70 of about 21,807 (192)

Capnocytophaga canimorsus Septicaemia Presenting With Multiorgan Dysfunction Syndrome (MODS) and Disseminated Intravascular Coagulation (DIC) in an Immunocompetent Individual

open access: yesCase Reports in Critical Care, Volume 2026, Issue 1, 2026.
We present a rare case of fulminant Capnocytophaga canimorsus septicaemia in a previously well 52‐year‐old immunocompetent woman, following a minor dog‐related forehead abrasion. Despite a recent course of amoxicillin/clavulanate prescribed by her general practitioner, the patient developed profound sepsis characterised by disseminated intravascular ...
Kadison Michel   +3 more
wiley   +1 more source

Intrauterine purpura fulminans

open access: yesThe Turkish Journal of Pediatrics, 1975
S Ozsoylu, S Bektaş
doaj   +2 more sources

Use of Double Dose Intravenous Immunoglobulin Therapy in the Treatment of Streptococcal Toxic Shock Syndrome

open access: yesCase Reports in Critical Care, Volume 2026, Issue 1, 2026.
Streptococcal toxic shock syndrome (STSS) is a life‐threatening condition with increasing incidence and high mortality worldwide. It is characterised by hypotension and multiorgan failure, resultant of invasive group A Streptococcus (GAS) infections. Intravenous immunoglobulin (IVIG) has been proposed as an adjunctive therapy that reduces mortality in ...
Yuning Xue, Alex Yartsev, Lipi Buch
wiley   +1 more source

Current Understanding of Meningitis Pathogens, Immunity Gap, and Future Prevention Strategies in Sri Lanka: A Narrative Review

open access: yesInternational Journal of Microbiology, Volume 2026, Issue 1, 2026.
Meningitis, an acute and life‐threatening inflammation of the protective membranes covering the brain and spinal cord caused primarily by bacterial, viral, fungal, or parasitic infections, remains a major global health challenge, causing significant morbidity and mortality, particularly among children and vulnerable populations.
Thashmila Heshani   +5 more
wiley   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami   +2 more
wiley   +1 more source

A Rare Case of Acute Infectious Purpura Fulminans Caused by Klebsiella Pneumoniae and Human Herpesvirus Type 5

open access: yes, 2022
Xiao-Lan Li,1 Chun-Yan Luan,1 Ying-Jun Fan,2 Xiao-Ying Lin,1 Dong Jiang,1 Mei-Xian Su,3 Gang Wang,4 Xu Yang5 1Department of Dermatology, The Second Affiliated Hospital of Kunming Medical University, Kunming, 650101, People’s Republic of China ...
Yang X   +7 more
core  

Purpura Fulminans with Peripheral Gangrene in severe Falciparum Malaria: a case series [PDF]

open access: yes, 2019
Background: Purpura fulminans is an acute fatal illness consisting of septicaemia, shock, and disseminated intravascular coagulation, often manifesting with gangrene of the distal extremities and necrosis of skin.
Aigbovo, E. O.   +3 more
core   +1 more source

CASE OF PURPURA FULMINANS [PDF]

open access: yesJournal of the American Medical Association, 1909
The patient was a healthy young man, aged 18. He awoke in the morning with a severe sore throat. He used hydrogen peroxid as a gargle and went to work as usual. In the evening his throat was not much better, so he used the peroxid gargle again. The next morning I was summoned and found him with a temperature of 106 F.
openaire   +2 more sources

Invasive Meningococcal Disease in a Patient With Complement 7 Deficiency

open access: yesJournal of General and Family Medicine, Volume 26, Issue 6, Page 646-649, November 2025.
ABSTRACT Neisseria meningitidis can cause invasive meningococcal disease (IMD). Individuals with primary complement deficiencies are at a higher risk of developing IMD. However, cases of IMD associated with complement deficiency have rarely been reported in Japan.
Hiroaki Nishioka   +2 more
wiley   +1 more source

Necrotizing Fasciitis of Eyelid in Children: A Rare Complication of Varicella Infection

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Necrotizing fasciitis (NF) of the eyelid is an extremely rare but severe complication of varicella zoster virus (VZV) infection in children. We present a case of an 8‐year‐old girl who developed necrotizing fasciitis of the left eyelid following varicella infection.
Govinda Bhandari   +2 more
wiley   +1 more source

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