Results 41 to 50 of about 7,493 (166)

Paradoxical Alopecia Areata Induced by IL‐17 and IL‐23 Inhibitors: A Systematic Review

JEADV Clinical Practice, EarlyView.
This systematic review identifies consistent clinical patterns of alopecia areata associated with IL‐17 and IL‐23 inhibitors, most frequently involving secukinumab and ustekinumab. Disease severity varied widely, and management often required biologic discontinuation or therapeutic switching.
Isabella Kamholtz, Simonetta I. Gaumond, Joaquin J. Jimenez   +2 more
wiley   +1 more source

Subcorneal Pustular Dermatosis, a Systematic Review and Pooled Analysis of a Rare and Underdiagnosed Disease

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Subcorneal pustular dermatosis (SPD), or Sneddon–Wilkinson disease, is a rare, relapsing pustular skin condition of unknown cause, characterised by subcorneal pustules. Objectives To summarise the demographic, clinical, histopathological, management and disease course of SPD.
Mason H. Crossman, Jeffrey Weng, Alysha Vuong, Lawrence Lin, Zhao Feng Liu, Christopher Y. Chew   +5 more
wiley   +1 more source

Amicrobial Pustulosis of the Folds: Report of Three New Cases

, 2020
Amicrobial Pustulosis of the Folds: Report of Three New ...
Martina Maurelli, Francesco Bellinato, Chiara Colato, Giampiero Girolomoni   +3 more
core   +1 more source

Real World Use of the IL‐36 Receptor Antagonist Spesolimab: A Systematic Review and Analysis

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Spesolimab, an interleukin‐36 receptor antagonist, is approved for the treatment and prevention of generalised pustular psoriasis (GPP) flares. Its use has increasingly been reported in real‐world settings for both GPP and other inflammatory dermatoses.
Sophia A. Mense, Nicole Bavaro, Aashna Farishta, Jiaqi Chen, Raj Chovatiya   +4 more
wiley   +1 more source

SAPHO syndrome with a purely osteolytic form: A case report

Radiology Case Reports, 2023
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare, chronic autoinflammatory disorder that can present with a constellation of cutaneous and osteoarticular symptoms.
Akira Kakiuchi, MD, Yayoi Yamamoto, MD, PhD, Akira Kanbe, MD, Daichi Kojima, MD, Ayako Hino, MD, PhD, Ayumi Horikawa, MD, PhD, Tsunehiro Doiuchi, MD, Hiroaki Kurihara, MD, PhD   +7 more
doaj   +1 more source

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

Allergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud, Lene Heise Garvey, Elizabeth Phillips, Michael Ardern‐Jones, Sevim Bavbek, Patrizia Bonadonna, Jean‐Christoph Caubet, Ana‐Maria Copaescu, Valentina Gueli, Jose Julio Laguna, Ricardo Madrigal‐Burgaleta, Francesca Mori, Vito Sabato, Maria J Torres, Knut Brockow   +14 more
wiley   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean‐Christoph Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

Pustulosis exantemática generalizada aguda no medicamentosa, una entidad para recordar [PDF]

, 2019
Acute generalized exanthematous pustulosis is an infrequent entity, 90% of the cases are associated with the ingestion of drugs. Scarce reports exist re­garding non drug-related acute generalized exanthematous pustulosis, the tri­gger factors described ...
Ordóñez, María Fernanda, Giraldo, Daniela, Robayo, Martha Patricia   +2 more
core  

Acute generalized exanthematous pustulosis due to dextromethorphan [PDF]

, 2013
Acute generalized exanthematous pustulosis (AGEP) is a rare, severe, pustular, cutaneous reaction. We report a case in which a patient developed AGEP after the intake of 3 different antitussive agents containing dextromethorphan as the only ingredient in
Perez Paredes, G., Rodriguez Prieto, M.A., Otero Rivas, M.M., Sanchez Sambucety, P., Garcia-Ruiz de Morales, J.M., Otero Rivas, M.M. ; Sanchez Sambucety, P. ; Garcia-Ruiz de Morales, J.M. ; Perez Paredes, G. ; Rodriguez Prieto, M.A., P. Sanchez Sambucety, G. Perez Paredes, M.M. Otero Rivas, J.M. Garcia-Ruiz de Morales, M.A. Rodriguez Prieto   +10 more
core   +1 more source

The interleukin 1 receptor antagonist anakinra to reduce disease severity of palmoplantar pustulosis in adults: APRICOT RCT and PLUM mechanistic study

Efficacy and Mechanism Evaluation, 2022
Background: Palmoplantar pustulosis is a rare, debilitating, chronic skin disease involving the hands and feet, and there are limited treatment options. Mechanistic findings suggest that interleukin 1 may be a pathogenic driver.
Suzie Cro, Victoria Cornelius, Francesca Capon, Jonathan Barker, David Burden, Christopher Griffiths, Helen Jane Lachmann, Helen McAteer, Prakash Patel, Andrew Pink, Nick Reynolds, Richard Warren, Catherine Smith   +12 more
doaj   +1 more source