Results 41 to 50 of about 32,576 (231)
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Germinated sorghum (Sorghum bicolor L.) and seedlings show expressive contents of putrescine. [PDF]
, 2022 Free bioactive amines were quantified during germination of tannin and tannin-free sorghum seeds (8 genotypes) and seedlings (2 genotypes). Among the ten amines investigated, three (putrescine, spermidine and spermine) were found.
PAIVA, C. L. +10 more
core +1 more source
Putrescine catabolism in mammalian brain [PDF]
Biochemical Journal, 1974 In contrast with putrescine (1,4-diaminobutane), which is a substrate of diamine oxidase, monoacetylputrescine is oxidatively deaminated both in vitro and in vivo by monoamine oxidase. The product of this reaction is N-acetyl-γ-aminobutyrate. The existence of a degradative pathway in mammalian brain for putrescine is shown, which comprises acetylation ...
N, Seiler, M J, Al-Therib
openaire +2 more sources
The Smell of Death: Evidence that Putrescine Elicits Threat Management Mechanisms
Frontiers in Psychology, 2015 The ability to detect and respond to chemosensory threat cues in the environment plays a vital role in survival across species. However, little is known about which chemical compounds can act as olfactory threat signals in humans.
Arnaud eWisman, Ilan eShrira
doaj +1 more source
TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
Advanced Science, EarlyView.A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
Conformational Stabilization of Rat S-Adenosylmethionine Decarboxylase by Putrescine [PDF]
, 2010 The activity and processing of mammalian S-adenosylmethionine decarboxylase (AdoMetDC) is stimulated by putrescine. To obtain new insights into the mechanism through which putrescine stimulates AdoMetDC, we investigated conformational changes in rat ...
白幡, 晶 +3 more
core +1 more source
Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia
Advanced Science, EarlyView.The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian +12 more
wiley +1 more source
Effect of mycorrhizal fungi and foliar application of putrescine on some biochemical characteristics and biomass of basil (Ocimum ciliatum L.) in two different harvesting times [PDF]
فیزیولوژی محیطی گیاهی, 2019 In order to investigate the effect of mycorrhizal fungi and foliar application of putrescine on some biochemical characteristics, essential oil content, and biomass of basil (Ocimumciliatum L.), a split plot in time experiment with three replications was
Sara Farsari, Mohammad Moghaddam
doaj
Advanced Science, EarlyView.A high‐throughput screening platform was established by integrating an in vivo cadaverine biosensor with a fluorescence‐activated cell sorting (FACS) system. Biosensor‐driven specific exporter tuning, pathway optimization and genome‐wide target mining were conducted to maximize cadaverine production in Escherichia coli.
Jia Feng +13 more
wiley +1 more source
Carrier-Mediated Process of Putrescine Elimination at the Rat Blood–Retinal Barrier
, 2023 Putrescine is a bioactive polyamine. Its retinal concentration is strictly controlled to maintain a healthy sense of vision. The present study investigated putrescine transport at the blood–retinal barrier (BRB) to gain a better understanding of ...
Hiroaki Miura +6 more
core +1 more source