Physical and Chemical Inactivators Evaluation for the Puumala Virus Vaccine Technology Development
Relevance. Hemorrhagic fever with renal syndrome (HFRS) is leading among natural focal human diseases in Russia, the causative agents of which - orthohantaviruses - belong to the order Bunyavirales, family Hantaviridae.
S. S. Kurashova +8 more
doaj +1 more source
Truncated recombinant puumala virus nucleocapsid proteins protect mice against challenge in vivo
In Europe, Puumala virus and Dobrava virus are the major hantaviruses that cause hemorrhagic fever with renal syndrome in humans. As hantaviruses can cause diseases with high morbidity and mortality rates, and as to date there is no specific treatment ...
Clement, Jan +6 more
core +1 more source
Detection of Antibodies Recognizing Puumala Virus Nucleocapsid and Glycoprotein Peptides in NE Serum [PDF]
© 2016, Springer Science+Business Media New York.Nephropatia epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS), is an endemic zoonosis in the Republic of Tatarstan, Russia.
Shakirova V. +8 more
core
cas imageDiffusion spatiotemporelle du virus Puumala en Europe de l'Ouest représentée sur une carte issue du serveur ...
Murri, Séverine +4 more
core +1 more source
Risk Factors for Human Infection with Puumala Virus, Southwestern Germany
Puumala virus, which causes nephropathia epidemica (NE), is the most prevalent hantavirus in Germany; bank voles serve as the main reservoir. During 2001-2007, most NE cases reported from Germany occurred in the southwestern state of Baden-Württemberg.
Schwarz, Anne Caroline +4 more
openaire +3 more sources
Detection of Antibodies Recognizing Puumala Virus Nucleocapsid and Glycoprotein Peptides in NE Serum
© 2016, Springer Science+Business Media New York.Nephropatia epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS), is an endemic zoonosis in the Republic of Tatarstan, Russia.
Shakirova V. +8 more
core
In-cell Western assay to quantify infection with pathogenic orthohantavirus Puumala virus in replication kinetics and antiviral drug testing. [PDF]
Nusshag C +4 more
europepmc +1 more source
Bunyamwera bunyavirus nonstructural protein NSs counteracts the induction of alpha/beta interferon
Production of alpha/beta interferons (IFN-α/β) in response to viral infection is one of the main defense mechanisms of the innate immune system. Many viruses therefore encode factors that subvert the IFN system to enhance their virulence.
Richard E. Randall +29 more
core +1 more source
Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses. [PDF]
Mittler E +28 more
europepmc +1 more source
Phage-displayed peptide targeting on the Puumala hantavirus neutralization site
We have selected ligands for Puumala hantavirus, the causative agent of nephropathia epidemica, from a seven-amino-acid peptide library flanked by cysteines and displayed on a filamentous phage.
Lankinen, H +3 more
core +1 more source

