Results 81 to 90 of about 5,652 (231)

Natural Focal Viral Fevers in the South of the European Part of Russia. Hemorrhagic Fever with Renal syndrome

Проблемы особо опасных инфекций, 2020
Objective of the study was to determine the modem epizootic and epidemic peculiarities of hemorrhagic fever with renal syndrome in the south of the European part of Russia. Materials and methods.
O. V. Maletskaya, T. V. Taran, D. A. Prislegina, A. E. Platonov, V. M. Dubyansky, A. S. Volynkina, N. F. Vasilenko, Yu. N. Tokhov, N. V. Tsapko   +8 more
doaj   +1 more source

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

WIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus, Eliana Dukhno, Rupali Kapoor, Piotr Gerlach   +3 more
wiley   +1 more source

Squirrelpox virus: assessing prevalence, transmission and environmental degradation [PDF]

, 2014
Red squirrels (Sciurus vulgaris) declined in Great Britain and Ireland during the last century, due to habitat loss and the introduction of grey squirrels (Sciurus carolinensis), which competitively exclude the red squirrel and act as a reservoir for ...
AC Scott, AD Middleton, AR Bharti, AW Sainsbury, AW Sainsbury, B Carroll, Christopher James Johnson, CJ McInnes, CJ McInnes, CM Bruemmer, Colin McInnes, CW Livingston, D Sweet, David Everest, David G. Tosh, DJ Everest, DJ Everest, DM Tompkins, ER Kallio, J Gurnell, Jaimie T. A. Dick, JP Duff, JP LaRose, JW Atkin, LA Wauters, Lisa M. Collins, Mike Scantlebury, Neil D. Warnock, Neil Reid, Nikki Marks, SP Rushton, VR Simpson, W. Ian Montgomery   +32 more
core   +2 more sources

Hantaan virus glycoprotein Gc induces NEDD4‐dependent PTEN ubiquitination and degradation to escape the restriction of autophagosomes and facilitate viral propagation

The FASEB Journal, Volume 39, Issue 1, 15 January 2025.
The proposed model of HTNV induced PTEN degradation and PTEN‐regulated autophagy in progeny virus production: In HTNV‐infected HK‐2 cells, the viral Gc glycoprotein specifically promotes NEDD4 mediated ubiquitination and degradation of PTEN. Disruption of PTEN expression prevents autophagosome formation and increases HTNV production, whereas ...
Shuang Lu, Shuliang Chen, Yuqing Zhang, Xiaoli Mou, Mingyang Li, Shaowei Zhu, Xingyuan Chen, Tomas M. Strandin, Yale Jiang, Zhoufu Xiang, Yuanyuan Liu, Hairong Xiong, Deyin Guo, Liangjun Chen, Yirong Li, Wei Hou, Fan Luo   +16 more
wiley   +1 more source

Sequential assessment of clinical and laboratory parameters in patients with hemorrhagic fever with renal syndrome. [PDF]

PLoS ONE, 2018
BACKGROUND:Information on the sequential appearance, duration, and magnitude of clinical and laboratory parameters in hemorrhagic fever with renal syndrome (HFRS) is limited.
Emil Pal, Miša Korva, Katarina Resman Rus, Nataša Kejžar, Petra Bogovič, Anica Kurent, Tatjana Avšič-Županc, Franc Strle   +7 more
doaj   +1 more source

Case report: Hemorrhagic fever with renal syndrome presenting as hemophagocytic lymphohistiocytosis

Frontiers in Medicine, 2022
Hemophagocytic lymphohistiocytosis may occur in patients with genetic predisposition and in sporadic cases due to malignancy or infection. We describe a 49-year old man with hemorrhagic fever, type 1 respiratory insufficiency and acute kidney injury ...
Maarten A. J. De Smet, Simon Bogaert, Alexander Schauwvlieghe, Amélie Dendooven, Pieter Depuydt, Patrick Druwé   +5 more
doaj   +1 more source

Acute kidney injury and tools for risk-stratification in 456 patients with hantavirus-induced nephropathia epidemica [PDF]

, 2017
BACKGROUND Puumala virus (PUUV) is the most common species of hantavirus in Central Europe. Nephropathia epidemica (NE), caused by PUUV, is characterized by acute kidney injury (AKI) and thrombocytopenia.
Alscher, M Dominik, Braun, Niko, Brockmann, Stefan, Corea, Angela, Dippon, Juergen, Fritz, Peter, Gußmann, Karl, Hoffmann, Larissa, Kimmel, Martin, Kitterer, Daniel, Latus, Joerg, Mezger, Barbara, Müller, Simon, Pieper, Friedrich-Michael, Priwitzer, Martin, Pöhlmann, Christoph, Rettenmaier, Bianka, Schwab, Andrea, Schwab, Matthias, Segerer, Stephan, Tacconelli, Evelina, Walter-Frank, Birgit, Wegener, Daniel, Wiedenmann, Albrecht, Zakim, David   +24 more
core  

Complex evolution and epidemiology of Dobrava-Belgrade hantavirus: definition of genotypes and their characteristics. [PDF]

, 2013
Dobrava-Belgrade virus (DOBV) is a human pathogen that has evolved in, and is hosted by, mice of several species of the genus Apodemus. We propose a subdivision of the species Dobrava-Belgrade virus into four related genotypes – Dobrava, Kurkino ...
Avsic-Zupanc, T., Clement, J., Dzagurova, T.K., Henttonen, Heikki, Heyman, P., Jakab, F., Klempa, B., Kruger, D.G., Maes, P., Papa, A., Tkachenko, A.A., Ulrich, R.G., Vaheri, A., Vapalahti, O.   +13 more
core   +1 more source

Reduction in mucosal‐associated invariant T cells (MAIT) in APECED patients is associated with elevated serum IFN‐γ concentration

European Journal of Immunology, Volume 54, Issue 12, December 2024.
We found a reduced frequency of circulating mucosal‐associated invariant T cells (MAITs) in patients with APECED with a clear negative correlation to inflammatory markers CRP, IL‐18, and IFN‐γ. These findings suggest that the decrease in MAITs is secondary to type 1 immune dysregulation present in the disease.
Iivo Hetemäki, Joona Sarkkinen, Huai Hui Wong, Nelli Heikkilä, Saila Laakso, Simo Miettinen, Mikko I. Mäyränpää, Outi Mäkitie, T Petteri Arstila, Eliisa Kekäläinen   +9 more
wiley   +1 more source

Hantavirus infection-induced B cell activation elevates free light chains levels in circulation.

PLoS Pathogens, 2021
In humans, orthohantaviruses can cause hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS). An earlier study reported that acute Andes virus HPS caused a massive and transient elevation in the number of circulating ...
Jussi Hepojoki, Luz E Cabrera, Satu Hepojoki, Carla Bellomo, Lauri Kareinen, Leif C Andersson, Antti Vaheri, Satu Mäkelä, Jukka Mustonen, Olli Vapalahti, Valeria Martinez, Tomas Strandin   +11 more
doaj   +1 more source