Results 51 to 60 of about 299,979 (268)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Fabrication and Characterisation of Stimuli Responsive Piezoelectric PVDF and Hydroxyapatite-Filled PVDF Fibrous Membranes [PDF]
Molecules, 2019 Poly(vinylidene fluoride) has attracted interest from the biomaterials community owing to its stimuli responsive piezoelectric property and promising results for application in the field of tissue engineering. Here, solution blow spinning and electrospinning were employed to fabricate PVDF fibres and the variation in resultant fibre properties assessed.
Biranche Tandon +4 more
openaire +4 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
PolimeryThe influence of TEOS on the rheological properties of PVDF and poly(vinylidene fluoride-co-hexafluoropropylene) was investigated. The addition of TEOS to low molecular weight PVDF results in pseudoplastic behavior. The exception is PVDF containing 5 wt%.
Monis Bin Abid +4 more
doaj +1 more source
The Effect of SWCNT and MWCNT on Properties and Crystalline Structure of Polyvinylidene Fluoride [PDF]
علوم و تکنولوژی پلیمر, 2012 Single-walled carbon nanotubes (SWCNT) and multi-walled carbon nanotubes(MWCNT) were melt-blended with polyvinylidene fluoride (PVDF).FT-IR technique revealed that SWCNT has insignificant effect on the crystalline structure of PVDF and at 3wt ...
Ali Akbar Yousefi
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
تنظیم عملگری نانوالیاف پیزوالکتریک پلی(وینیلیدن فلوئورید)/کلویزیت 30B [PDF]
علوم و تکنولوژی پلیمرفرضیه: محرک‌های پیزوالکتریک که می‌توانند انرژی الکتریکی را به انرژی مکانیکی تبدیل کنند، در سامانه‌های رباتیک، ابزارهای پزشکی، ماهیچه‌های مصنوعی و دستگاه‌های الکترونیکی مورد توجه قرار گرفته‌اند.
سبحان شرف‌خانی
doaj +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source