Results 241 to 250 of about 12,133,346 (298)

Effect of phencyclidines on hippocampal pyramidal cells

Brain Research, 1982
Phencyclidine (PCP) and several behaviorally active or inactive structural analogs were administered i.v. to urethane-anesthetized rats in order to determine their effects on CA1 pyramidal cell discharges elicited by contralateral CA3 (cCA3) stimulation.
J L, Stringer, P G, Guyenet
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Reduced compartmental models of neocortical pyramidal cells

Journal of Neuroscience Methods, 1993
Model neurons composed of hundreds of compartments are currently used for studying phenomena at the level of the single cell. Large network simulations require a simplified model of a single neuron that retains the electrotonic and synaptic integrative properties of the real cell.
P C, Bush, T J, Sejnowski
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Basilar dendrite bundles of giant pyramidal cells

Experimental Neurology, 1974
Abstract Giant pyramidal cells of Betz from primary motor cortex and large solitary cells of Meynert from the visual cortex appear to share certain characteristics including extraordinary length of their basilar dendrites and the organization of these dendrite shafts into bundles.
M E, Scheibel, T L, Davies, R D, Lindsay, A B, Scheibel   +3 more
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Cholinergic excitation of mammalian hippocampal pyramidal cells

Brain Research, 1982
Responses of CA1 pyramidal neurons to ACh were recorded with intracellular microelectrodes utilizing the in vitro guinea pig hippocampal slice preparation. ACh was delivered by drop or iontophoretic application to stratum oriens or stratum radiatum. Threshold dose for drop application was 1 mM.
L S, Benardo, D A, Prince
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Cholinergic pharmacology of mammalian hippocampal pyramidal cells

Neuroscience, 1982
Responses of CAl pyramidal cells to cholinergic compounds were recorded with intracellular microelectrodes in guinea-pig hippocampal slices. Perfusion of slices with medium containing the muscarinic antagonists atropine or scopolamine (10(-7)-10(-6)M) blocked all actions of acetylcholine.
L S, Benardo, D A, Prince
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Mechanisms of Electrical Coupling Between Pyramidal Cells

Journal of Neurophysiology, 1997
Vigmond, Edward J., Jose L. Perez Velazquez, Taufik A. Valiante, Berj L. Bardakjian, and Peter L. Carlen. Mechanisms of electrical coupling between pyramidal cells. J. Neurophysiol. 78: 3107–3116, 1997. Direct electrical coupling between neurons can be the result of both electrotonic current transfer through gap junctions and extracellular fields ...
E J, Vigmond, J L, Perez Velazquez, T A, Valiante, B L, Bardakjian, P L, Carlen   +4 more
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Ratio of pyramidal cells versus non-pyramidal cells in sector CA1 of the human Ammon's horn

Anatomy and Embryology, 1985
Combined Golgi/pigment studies revealed that pyramidal neurons and non-pyramidal cells of the Ammon's horn of the human adult can be distinguished from each other by their characteristic lipofuscin pigment deposits. In sector CA1, both the typical pyramidal neurons and the modified forms of pyramidal cells contain a modest amount of fine lipofuscin ...
H G, Olbrich, H, Braak
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Excitatory synapses from CA3 pyramidal cells onto neighboring pyramidal cells differ from those onto inhibitory interneurons

Synapse, 2001
AbstractThe glutamatergic pyramidal cell (PYR) to pyramidal cell synapse was compared to the PYR to inhibitory interneuron (INT) synapse in area CA3 of rat hippocampal roller‐tube cultures. Paired‐pulses and tetanic stimulations of a presynaptic PYR were conducted utilizing dual whole‐cell patch‐clamp recordings of either two PYRs or of a PYR and ...
G B, Aaron, M A, Dichter
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Some Mechanisms Controlling Hippocampal Pyramidal Cells

1983
Publisher Summary Early studies of the neuromuscular junction and on motoneurons formed certain classical concepts about mechanisms controlling excitable cells. Excitation was shown to be caused by a relatively non-specific permeability increase of the synaptic membrane (“short-circuit”), while inhibition was shown to be because of a specific ...
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Pyramidal Nerve Cell Loss in Alzheimer's Disease

Neurodegeneration, 1996
Loss of the large pyramidal cells of the association neocortex and hippocampus, along with plaques and tangles, is fundamental to the neuropathology of Alzheimer's disease. The extent of Alzheimer-specific cell loss, relative to controls, is age-dependent with maximal losses in younger subjects though, because of the (additive) effects of 'normal ...
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