Results 91 to 100 of about 267,739 (297)

The time window for generation of dendritic spikes by coincidence of action potentials and EPSPs is layer specific in somatosensory cortex. [PDF]

PLoS ONE, 2012
The precise timing of events in the brain has consequences for intracellular processes, synaptic plasticity, integration and network behaviour. Pyramidal neurons, the most widespread excitatory neuron of the neocortex have multiple spike initiation zones,
Debora Ledergerber, Matthew Evan Larkum
doaj   +1 more source

Flexible Sensors for Robotics Tactile Perception: A Review

Advanced Robotics Research, EarlyView.
Flexible tactile sensing for robotics is reviewed through four interconnected dimensions. Physical mechanisms include piezoresistive, capacitive, piezoelectric, triboelectric, iontronic, and optical sensing. Structural design includes bioinspired, defect‐based, and MEMS‐based tactile systems.
Yu Song, Ying Chen, Yihao Chen, Xue Feng
wiley   +1 more source

Human Cerebral Cortex Cajal-Retzius Neuron: Development, Structure and Function. A Golgi Study

Frontiers in Neuroanatomy, 2015
The development, morphology and possible functional activity of the Cajal-Retzius cell of the developing human cerebral cortex have been explored herein. The C-RC, of extracortical origin, is the essential neuron of the neocortex first lamina.
Miguel eMarín-Padilla
doaj   +1 more source

A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans

Advanced Science, EarlyView.
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao, Yu‐Xin Zhang, Xiao‐Xing Liu, Zi‐Hang Li, Tang‐Sheng Lu, Jia‐Hui Deng, Wen Zhang, Peng Li, Xiao Lin, Shu‐Fei Feng, Ting‐Ting Li, Shi‐Qiu Meng, Xiang‐Dong Tang, Tian‐Ye Jia, Trevor W. Robbins, Jie Shi, Ying Han, Yan‐Xue Xue, Lin Lu, Kai Yuan   +19 more
wiley   +1 more source

Perspective on the Multiple Pathways to Changing Brain States

Frontiers in Systems Neuroscience, 2020
In this review article, we highlight several disparate ideas that are linked to changes in brain state (i.e., sleep to arousal, Down to Up, synchronized to de-synchronized).
Malinda L. S. Tantirigama, Timothy Zolnik, Benjamin Judkewitz, Matthew E. Larkum, Robert N. S. Sachdev   +4 more
doaj   +1 more source

Pyramidal neurons of CA1 neuron in organotypic slice

Alzheimer's & Dementia
AbstractThis is a maximal intensity projection of CA1 pyramidal cell transfected with plasmid with the reporter GFP using single cell electroporation technique. In this particular case the organotypic slices were prepared from p5‐7 pups in a tissue chopper (McIlwain).
Roy, Avishek, Deforges, Severine, Mulle, Christophe   +2 more
openaire   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Unexpected Efficacy of a Novel Sodium Channel Modulator in Dravet Syndrome

Scientific Reports, 2017
Dravet syndrome, an epileptic encephalopathy affecting children, largely results from heterozygous loss-of-function mutations in the brain voltage-gated sodium channel gene SCN1A.
Lyndsey L. Anderson, Nicole A. Hawkins, Christopher H. Thompson, Jennifer A. Kearney, Alfred L. George   +4 more
doaj   +1 more source

Pyramidal neurons do not exhibit DAF-2DA fluorescence.

, 2013
(A) IR/DIC image of a recorded pyramidal neuron (arrow) and the patch pipette. Scale bar = 25 µm. (B) Fluorescence image of the recording region, revealing fluorescent cells other than the recorded one.
Yifat Levi (78862), Yasmin Abu-Ghanem (78861), Ettie Grauer (78864), Yossi Buskila (78860), Yael Amitai (33580), Arie Moran (78863)   +5 more
core   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source