Results 1 to 10 of about 4,864,845 (302)

Effect of juvenile social isolation on excitability of prefrontal pyramidal cells with different subcortical axonal projections [PDF]

open access: yesFrontiers in Cellular Neuroscience
BackgroundSocial experience during development is crucial for the functional maturation of the prefrontal cortex (PFC). Juvenile social isolation (JSI) causes severe PFC dysfunction. JSI reduces intrinsic excitability and excitatory synaptic inputs for a
Yosuke Nishihata   +11 more
doaj   +3 more sources

The Dendritic Density Field of a Cortical Pyramidal Cell [PDF]

open access: yesFrontiers in Neuroanatomy, 2012
Much is known about the computation in individual neurons in the cortical column. Also, the selective connectivity between many cortical neuron types has been studied in great detail. However, due to the complexity of this microcircuitry its functional role within the cortical column remains a mystery. Some of the wiring behavior between neurons can be
Hermann Cuntz   +3 more
openaire   +7 more sources

Regulating firing rate of networks of pyramidal cells

open access: yesNeurocomputing, 2001
Abstract In a minimal network model consisting of two pyramidal cells and one interneuron, we show how excitation and inhibition cooperate to produce firing rate changes in pyramidal cells that are consistent with observed place cell firing in region CA3 of the hippocampus. We show that inhibition from a common interneuron can synchronize networks of
Victoria Booth, Amitabha Bose
openaire   +3 more sources

Pyramidal Cells in Olfactory Cortex. [PDF]

open access: yesChem Senses, 2021
Abstract The neocortex and olfactory cortices share many features including their laminar organization, developmental sequences, and cell types. Previous work indicates that neocortical pyramidal cells exhibit a gradient of dendritic size: cells involved in the initial processing of information are less complex than those in subsequent ...
Brunjes PC.
europepmc   +4 more sources

All active hippocampal pyramidal cells are place cells. [PDF]

open access: yesiScience
Hippocampal place cells - neurons whose activity is modulated by spatial position - are considered an essential substrate of spatial cognition. Despite decades of research, the fraction of hippocampal place cells remains debated, with studies reporting between 20% and 90% of the recorded populations. This raises the question of whether distinct subsets
Talpir I, Sheintuch L, Rubin A, Ziv Y.
europepmc   +3 more sources

The increased in vivo firing of pyramidal cells but not interneurons in the anterior cingulate cortex after neuropathic pain

open access: yesMolecular Brain, 2022
Chronic pain damages the balance between excitation and inhibition in the sensory cortex. It has been confirmed that the activity of cortical glutamatergic pyramidal cells increases after chronic pain.
Da-Yu Zhu   +9 more
doaj   +1 more source

Layer III pyramidal cells in the prefrontal cortex reveal morphological changes in subjects with depression, schizophrenia, and suicide

open access: yesTranslational Psychiatry, 2022
Brodmann Area 46 (BA46) has long been regarded as a hotspot of disease pathology in individuals with schizophrenia (SCH) and major depressive disorder (MDD).
Nick Y. Larsen   +9 more
doaj   +1 more source

Decreased density of pyramidal cells in the cerebral cortex, and Purkinje cells in the cerebellar cortex of Sprague-Dawley rats after being exposed to filtered kretek cigarette smoke

open access: yesJournal of Biological Research, 2023
Filtered kretek cigarette smoke is a gas that contains solid components (particulates). Carcinogenic chemicals are present in this type of cigarette smoke. Furthermore, it is said that tobacco has a major negative impact on cerebral structure development,
David Tjahyadi   +5 more
doaj   +1 more source

Cell-type specific innervation of cortical pyramidal cells at their apical dendrites

open access: yeseLife, 2020
We investigated the synaptic innervation of apical dendrites of cortical pyramidal cells in a region between layers (L) 1 and 2 using 3-D electron microscopy applied to four cortical regions in mouse.
Ali Karimi   +4 more
doaj   +1 more source

Expression of Brain Derived Growth Factor in Hippocampus of Mid Gestational Human Fetuses [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: Brain Derived Growth Factor (BDNF) is a sub member of neurotrophin family and is a critical regulator of formation and plasticity of neuronal networks in hippocampal formation.
Shilpi Garg, Sabita Mishra, Swati Tiwari
doaj   +1 more source

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