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Effect of juvenile social isolation on excitability of prefrontal pyramidal cells with different subcortical axonal projections [PDF]
BackgroundSocial experience during development is crucial for the functional maturation of the prefrontal cortex (PFC). Juvenile social isolation (JSI) causes severe PFC dysfunction. JSI reduces intrinsic excitability and excitatory synaptic inputs for a
Yosuke Nishihata +11 more
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The Dendritic Density Field of a Cortical Pyramidal Cell [PDF]
Much is known about the computation in individual neurons in the cortical column. Also, the selective connectivity between many cortical neuron types has been studied in great detail. However, due to the complexity of this microcircuitry its functional role within the cortical column remains a mystery. Some of the wiring behavior between neurons can be
Hermann Cuntz +3 more
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Regulating firing rate of networks of pyramidal cells
Abstract In a minimal network model consisting of two pyramidal cells and one interneuron, we show how excitation and inhibition cooperate to produce firing rate changes in pyramidal cells that are consistent with observed place cell firing in region CA3 of the hippocampus. We show that inhibition from a common interneuron can synchronize networks of
Victoria Booth, Amitabha Bose
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Pyramidal Cells in Olfactory Cortex. [PDF]
Abstract The neocortex and olfactory cortices share many features including their laminar organization, developmental sequences, and cell types. Previous work indicates that neocortical pyramidal cells exhibit a gradient of dendritic size: cells involved in the initial processing of information are less complex than those in subsequent ...
Brunjes PC.
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All active hippocampal pyramidal cells are place cells. [PDF]
Hippocampal place cells - neurons whose activity is modulated by spatial position - are considered an essential substrate of spatial cognition. Despite decades of research, the fraction of hippocampal place cells remains debated, with studies reporting between 20% and 90% of the recorded populations. This raises the question of whether distinct subsets
Talpir I, Sheintuch L, Rubin A, Ziv Y.
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Chronic pain damages the balance between excitation and inhibition in the sensory cortex. It has been confirmed that the activity of cortical glutamatergic pyramidal cells increases after chronic pain.
Da-Yu Zhu +9 more
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Brodmann Area 46 (BA46) has long been regarded as a hotspot of disease pathology in individuals with schizophrenia (SCH) and major depressive disorder (MDD).
Nick Y. Larsen +9 more
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Filtered kretek cigarette smoke is a gas that contains solid components (particulates). Carcinogenic chemicals are present in this type of cigarette smoke. Furthermore, it is said that tobacco has a major negative impact on cerebral structure development,
David Tjahyadi +5 more
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Cell-type specific innervation of cortical pyramidal cells at their apical dendrites
We investigated the synaptic innervation of apical dendrites of cortical pyramidal cells in a region between layers (L) 1 and 2 using 3-D electron microscopy applied to four cortical regions in mouse.
Ali Karimi +4 more
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Expression of Brain Derived Growth Factor in Hippocampus of Mid Gestational Human Fetuses [PDF]
Introduction: Brain Derived Growth Factor (BDNF) is a sub member of neurotrophin family and is a critical regulator of formation and plasticity of neuronal networks in hippocampal formation.
Shilpi Garg, Sabita Mishra, Swati Tiwari
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