Results 1 to 10 of about 103,358 (302)
Effect of juvenile social isolation on excitability of prefrontal pyramidal cells with different subcortical axonal projections [PDF]
Frontiers in Cellular NeuroscienceBackgroundSocial experience during development is crucial for the functional maturation of the prefrontal cortex (PFC). Juvenile social isolation (JSI) causes severe PFC dysfunction. JSI reduces intrinsic excitability and excitatory synaptic inputs for a
Yosuke Nishihata +11 more
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Pyramidal Cells in Olfactory Cortex. [PDF]
Chem Senses, 2021 Abstract The neocortex and olfactory cortices share many features including their laminar organization, developmental sequences, and cell types. Previous work indicates that neocortical pyramidal cells exhibit a gradient of dendritic size: cells involved in the initial processing of information are less complex than those in subsequent ...
Brunjes PC.
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All active hippocampal pyramidal cells are place cells. [PDF]
iScienceHippocampal place cells - neurons whose activity is modulated by spatial position - are considered an essential substrate of spatial cognition. Despite decades of research, the fraction of hippocampal place cells remains debated, with studies reporting between 20% and 90% of the recorded populations. This raises the question of whether distinct subsets
Talpir I, Sheintuch L, Rubin A, Ziv Y.
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Cell-type specific innervation of cortical pyramidal cells at their apical dendrites
eLife, 2020 We investigated the synaptic innervation of apical dendrites of cortical pyramidal cells in a region between layers (L) 1 and 2 using 3-D electron microscopy applied to four cortical regions in mouse.
Ali Karimi +4 more
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Excitatory and inhibitory effects of HCN channel modulation on excitability of layer V pyramidal cells. [PDF]
PLoS Computational Biology, 2022 Dendrites of cortical pyramidal cells are densely populated by hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, a.k.a. Ih channels. Ih channels are targeted by multiple neuromodulatory pathways, and thus are one of the key ion-channel ...
Tuomo Mäki-Marttunen +1 more
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Pyramidal cells make specific connections onto smooth (GABAergic) neurons in mouse visual cortex. [PDF]
PLoS Biology, 2014 One of the hallmarks of neocortical circuits is the predominance of recurrent excitation between pyramidal neurons, which is balanced by recurrent inhibition from smooth GABAergic neurons.
Rita Bopp +4 more
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Objective Morphological Classification of Neocortical Pyramidal Cells
Cerebral Cortex, 2019 A consensus on the number of morphologically different types of pyramidal cells (PCs) in the neocortex has not yet been reached, despite over a century of anatomical studies, due to the lack of agreement on the subjective classifications of neuron types, which is based on expert analyses of neuronal morphologies.
Lida Kanari +2 more
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Molecular Brain, 2022 Chronic pain damages the balance between excitation and inhibition in the sensory cortex. It has been confirmed that the activity of cortical glutamatergic pyramidal cells increases after chronic pain.
Da-Yu Zhu +9 more
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Translational Psychiatry, 2022 Brodmann Area 46 (BA46) has long been regarded as a hotspot of disease pathology in individuals with schizophrenia (SCH) and major depressive disorder (MDD).
Nick Y. Larsen +9 more
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Journal of Biological Research, 2023 Filtered kretek cigarette smoke is a gas that contains solid components (particulates). Carcinogenic chemicals are present in this type of cigarette smoke. Furthermore, it is said that tobacco has a major negative impact on cerebral structure development,
David Tjahyadi +5 more
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