Results 11 to 20 of about 4,864,845 (302)

Postnatal Development of the Hippocampus in Male Albino Rats: A Histomorphometric Study [PDF]

open access: yesThe Egyptian Journal of Histology, 2023
Introduction: In recent years, deterioration in cognitive, learning, and memory become one of the significant problems in human life. Hippocampus is a pivotal part of the brain’s limbic system which serves a critical role in memory, learning process and ...
Asmaa Ahmed   +3 more
doaj   +1 more source

Hippocampal pyramidal cells: the reemergence of cortical lamination [PDF]

open access: yesBrain Structure and Function, 2011
The increasing resolution of tract-tracing studies has led to the definition of segments along the transverse axis of the hippocampal pyramidal cell layer, which may represent functionally defined elements. This review will summarize evidence for a morphological and functional differentiation of pyramidal cells along the radial (deep to superficial ...
Slomianka, Lutz   +4 more
openaire   +5 more sources

Tonic Control of Secretory Acid Sphingomyelinase Over Ventral Hippocampal Synaptic Transmission and Neuron Excitability

open access: yesFrontiers in Cellular Neuroscience, 2021
The acid sphingomyelinase (ASM) converts sphingomyelin into ceramide. Recent work has advanced the ASM/ceramide system as a major player in the pathogenesis of major depressive disorder (MDD).
Chih-Hung Lin   +4 more
doaj   +1 more source

Subliminal messages in hippocampal pyramidal cells [PDF]

open access: yesThe Journal of Physiology, 2002
Synaptic activity regulates gene transcription in neurons. The coupling between synaptic transmission and transcription is accomplished by the second messenger calcium, which enters the cell through synaptic receptors and voltage-gated calcium channels and binds enzymes that activate transcription factors.
Thomas G, Oertner, Karel, Svoboda
openaire   +2 more sources

Presynaptic HCN channels constrain GABAergic synaptic transmission in pyramidal cells of the medial prefrontal cortex

open access: yesBiology Open, 2022
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are widely expressed in neurons in the central nervous system. It has been documented that HCN channels regulate the intrinsic excitability of pyramidal cells in the medial prefrontal ...
Wei Cai   +3 more
doaj   +1 more source

Change of Nurr1 expression in mouse hippocampal CA3 region following excitotoxic neuronal damage [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Objective(s): Nuclear receptor-related protein 1 (Nurr1), one of immediate-early genes, is a member of orphan nuclear receptor family. The aim of this study was to investigate the time-dependent change of Nurr1 protein expression in the mouse hippocampal
Choong-Hyun Lee
doaj   +1 more source

Postnatal development of dendritic calcium signaling in rat hippocampal pyramidal cells [PDF]

open access: yes, 2013
In CA1 pyramidal neurons, dendritic calcium transients in stratum radiatum were evoked in acute slices via backpropagating action potentials using patch clamp recordings.
Pohle, Jörg
core   +1 more source

Monosynaptic connections between pairs of spiny stellate cells in layer 4 and pyramidal cells in layer 5A indicate that lemniscal and paralemniscal afferent pathways converge in the infragranular somatosensory cortex. [PDF]

open access: yes, 2005
Monosynaptic interlaminar connections between spiny stellate cells in layer 4 (L4), the main cortical recipient layer for thalamic projections, and pyramidal cells in layer 5A (L5A), one of the main cortical output layers, were examined anatomically and ...
Feldmeyer, D   +5 more
core   +1 more source

Pyramidal cells in V1 of African rodents are bigger more branched and more spiny than those in primates.

open access: yesFrontiers in Neuroanatomy, 2014
Pyramidal cells are characterised by markedly different sized dendritic trees, branching patterns and spine density across the cortical mantle. Moreover, pyramidal cells have been shown to differ in structure among homologous cortical areas in different ...
Guy eElston, Paul eManger
doaj   +1 more source

Electrophysiological Heterogeneity of Fast-Spiking Interneurons: Chandelier versus Basket Cells [PDF]

open access: yes, 2013
In the prefrontal cortex, parvalbumin-positive inhibitory neurons play a prominent role in the neural circuitry that subserves working memory, and alterations in these neurons contribute to the pathophysiology of schizophrenia.
Povysheva, Nadezhda V.   +16 more
core   +2 more sources

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