Subliminal messages in hippocampal pyramidal cells [PDF]
The Journal of Physiology, 2002 Synaptic activity regulates gene transcription in neurons. The coupling between synaptic transmission and transcription is accomplished by the second messenger calcium, which enters the cell through synaptic receptors and voltage-gated calcium channels and binds enzymes that activate transcription factors.
Thomas G, Oertner, Karel, Svoboda
openaire +2 more sources
Electrophysiological Heterogeneity of Fast-Spiking Interneurons: Chandelier versus Basket Cells [PDF]
, 2013 In the prefrontal cortex, parvalbumin-positive inhibitory neurons play a prominent role in the neural circuitry that subserves working memory, and alterations in these neurons contribute to the pathophysiology of schizophrenia.
Povysheva, Nadezhda V. +16 more
core +1 more source
Modulation of medial prefrontal cortical activity using in vivo recordings and optogenetics
Molecular Brain, 2012 Background The medial prefrontal cortex (mPFC) serves major executive functions. mPFC output to subcortical brain areas such as the amygdala controls emotional processing and plays an important role in fear extinction.
Ji Guangchen, Neugebauer Volker
doaj +1 more source
The influence of GABAergic signaling on dendritic processing [PDF]
, 2013 GABAergic (?-aminobutyric acid-releasing) signaling plays a crucial role in integration processes of pyramidal neurons. Specific subtypes of GABA releasing interneurons innervate different compartments of pyramidal neurons; thereby modulating the ...
Willadt, Silvia
core +1 more source
Recurrent synapses and circuits in the CA3 region of the hippocampus: an associative network.
Frontiers in Cellular Neuroscience, 2014 In the CA3 region of the hippocampus, pyramidal cells excite other pyramidal cells and interneurons. The axons of CA3 pyramidal cells spread throughout most of the region to form an associative network.
Richard eMiles +4 more
doaj +1 more source
Age-related changes in the human primary motor cortex: A macroscopic and microscopic study
Asian Journal of Medical Sciences, 2021 Background: Cerebral hemisphere has outer gray matter and inner white matter. The cerebrum is folded into gyri and sulci in order to accommodate it in the skull. The thickness of the gray matter varies at sulci and gyri and the mean thickness may be from
Anne George , Usha K K
doaj +1 more source
Distinct roles of SOM and VIP interneurons during cortical Up states
Frontiers in Neural Circuits, 2016 During cortical network activity, recurrent synaptic excitation among pyramidal neurons is approximately balanced by synaptic inhibition, which is provided by a vast diversity of inhibitory interneurons.
Garrett T. Neske +2 more
doaj +1 more source
Neuroprotective effect of water lily (Nymphaea pubescens Willd) seed ethanolic extract against trimethyltin-induced cognitive impairment and neurodegeneration in mice [PDF]
Journal of HerbMed Pharmacology, 2023 Introduction: Cognitive impairments are profound outcomes of neurodegenerative disease, a global health issue. Water lily (Nymphaea pubescens, Nymphaeaceae) extracts have been reported to counteract oxidative stress.
Dinda Fadhilah Belahusna +2 more
doaj +1 more source
Adenosine A1 receptor activation mediates the developmental shift at layer 5 pyramidal cell synapses and is a determinant of mature synaptic strength [PDF]
, 2013 During the first postnatal month glutamatergic synapses between layer 5 pyramidal cells in the rodent neocortex switch from an immature state exhibiting high probability of neurotransmitter release, large unitary amplitude and synaptic depression to a ...
Richardson, Magnus J. E. +2 more
core +1 more source
Frontiers in Systems Neuroscience, 2014 The majority of neuronal cells found in the cerebral cortex are pyramidal neurons. Their function has been associated with higher cognitive and emotional functions. Pyramidal neurons have a characteristic structure, consisting of a triangular shaped soma
Maria Psarrou +3 more
doaj +1 more source