Results 31 to 40 of about 4,864,845 (302)

Drugs of Abuse Differentially Alter the Neuronal Excitability of Prefrontal Layer V Pyramidal Cell Subtypes

open access: yesFrontiers in Cellular Neuroscience, 2021
The medial prefrontal cortex (mPFC) plays an important role in regulating executive functions including reward seeking, task flexibility, and compulsivity.
Jonna M. Leyrer-Jackson   +2 more
doaj   +1 more source

Complementary Sensory and Associative Microcircuitry in Primary Olfactory Cortex [PDF]

open access: yes, 2011
The three-layered primary olfactory (piriform) cortex is the largest component of the olfactory cortex. Sensory and intracortical inputs converge on principal cells in the anterior piriform cortex (aPC).Wecharacterize organization principles of the ...
Dietmar Schmitz   +17 more
core   +1 more source

Genes, Cells and Brain Areas of Intelligence

open access: yesFrontiers in Human Neuroscience, 2019
What is the neurobiological basis of human intelligence? The brains of some people seem to be more efficient than those of others. Understanding the biological foundations of these differences is of great interest to basic and applied neuroscience ...
Natalia A. Goriounova   +1 more
doaj   +1 more source

The influence of GABAergic signaling on dendritic processing [PDF]

open access: yes, 2013
GABAergic (?-aminobutyric acid-releasing) signaling plays a crucial role in integration processes of pyramidal neurons. Specific subtypes of GABA releasing interneurons innervate different compartments of pyramidal neurons; thereby modulating the ...
Willadt, Silvia
core   +1 more source

Von Economo Neurons in the Human Medial Frontopolar Cortex

open access: yesFrontiers in Neuroanatomy, 2018
The von Economo neurons (VEN) are characterized by a large soma, spindle-like soma, with little dendritic arborization at both, the basal and apical poles.
Carlos Arturo González-Acosta   +4 more
doaj   +1 more source

Recurrent connections between CA2 pyramidal cells [PDF]

open access: yesHippocampus, 2018
Abstract Recurrent excitatory synapses are shown theoretically to play roles in memory storage and associative learning, and such recurrent synapses are well described to occur in the CA3 region of the hippocampus. Here, we report that the CA2 region also contains recurrent excitatory monosynaptic couplings.
Okamoto, Kazuki, Ikegaya, Yuji
openaire   +2 more sources

Age-dependent changes of p53 and p63 immunoreactivities in the mouse hippocampus

open access: yesLaboratory Animal Research, 2019
P53 and its family member p63 play important roles in cellular senescence and organismal aging. In this study, p53 and p63 immunoreactivity were examined in the hippocampus of young, adult and aged mice by using immunohistochemistry.
Tae-Kyeong Lee   +8 more
doaj   +1 more source

Morphological Characteristics of Electrophysiologically Characterized Layer Vb Pyramidal Cells in Rat Barrel Cortex. [PDF]

open access: yesPLoS ONE, 2016
Layer Vb pyramidal cells are the major output neurons of the neocortex and transmit the outcome of cortical columnar signal processing to distant target areas. At the same time they contribute to local tactile information processing by emitting recurrent
Jochen F Staiger   +3 more
doaj   +1 more source

Long-term potentiation at pyramidal cell to somatostatin interneuron synapses controls hippocampal network plasticity and memory

open access: yesiScience, 2022
Summary: Hippocampal somatostatin (SOM) cells are dendrite-projecting inhibitory interneurons. CA1 SOM cells receive major excitatory inputs from pyramidal cells (PC-SOM synapses) which show mGluR1a- and mTORC1-mediated long-term potentiation (LTP).
Azam Asgarihafshejani   +4 more
doaj   +1 more source

Computational Modeling of Genetic Contributions to Excitability and Neural Coding in Layer V Pyramidal Cells: Applications to Schizophrenia Pathology [PDF]

open access: yes, 2019
Pyramidal cells in layer V of the neocortex are one of the most widely studied neuron types in the mammalian brain. Due to their role as integrators of feedforward and cortical feedback inputs, they are well-positioned to contribute to the symptoms and ...
Einevoll, Gaute T   +8 more
core   +1 more source

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