Med Research, EarlyView.The AI‐enabled multimodal framework for whole‐life myopia management. Graphical abstract illustrates the transition of myopia care from premyopia to myopia, high myopia, and pathologic myopia. Multimodal data, including demographic and refractive information, genetic, behavioral and environmental factors, ophthalmic imaging, and omics profiles, can be ...
Zewei Zhang +6 more
wiley +1 more source
Inferring Parameters of Pyramidal Neuron Excitability in Mouse Models of Alzheimer's Disease Using Biophysical Modeling and Deep Learning. [PDF]
Bull Math BiolSaghafi S +6 more
europepmc +1 more source
Early Longitudinal Brain Network Changes in Huntington's Disease Before Clinical Motor Onset
Movement Disorders, EarlyView.Abstract Background Longitudinal studies of seed‐based functional connectivity (SBFC) in young adult Huntington's disease gene‐expanded (HDGE) individuals are rare, and none, to our knowledge, have examined adult cohorts decades from predicted clinical motor diagnosis.
Michela Leocadi +13 more
wiley +1 more source
Alfaxalone does not have long-term effects on goldfish pyramidal neuron action potential properties or GABA<sub>A</sub> receptor currents. [PDF]
FEBS Open BioDi Stefano D, Suganthan H, Buck L.
europepmc +1 more source
Deep‐Reorder: Refined Motion Correction for 3D Brain MRI via Iterative Data Regrouping
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose Accurate and temporally high‐resolution estimation of subject motion is paramount for effective motion‐correction in MRI. This work proposes a novel approach for estimating subject motion within a 3D MRI scan with high temporal resolution.
Laurens Beljaards +7 more
wiley +1 more source
Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Neuroprotection, EarlyView.Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source
Automatic insect identification, counting, and monitoring techniques: a review
Pest Management Science, EarlyView.Automated insect monitoring increasingly integrates optical, acoustic, infrared, radar, electrostatic, and biosensing technologies with artificial intelligence. No single approach is universally optimal; reliable deployment depends on task‐specific validation, representative datasets, robustness under field conditions, energy autonomy, connectivity ...
Mariano González García +3 more
wiley +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley +1 more source
Phytotherapy Research, EarlyView.Salidroside alleviates AlCl3/D‐galactose‐induced neuronal injury and synaptic dysfunction in AD‐like mice via regulation of the Keap1/Nrf2/GSH signaling axis. ABSTRACT Alzheimer's disease (AD) is associated with glutathione (GSH) depletion and redox imbalance in the brain, contributing to hippocampal neuronal damage and synaptic dysfunction and ...
Heying Cui +9 more
wiley +1 more source
[Enriched environment reduces pyramidal neuron excitability in the anterior cingulate cortex to alleviate restraint stress-induced anxiety-like behaviors in mice]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoChen C, Fang Q, Gao Y, Wang L, Chen L.
europepmc +1 more source