Results 81 to 90 of about 153,466 (237)

The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics

open access: yesAdvanced Science, EarlyView.
Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye   +5 more
wiley   +1 more source

Osmotic Edema Rapidly Increases Neuronal Excitability Through Activation of NMDA Receptor-Dependent Slow Inward Currents in Juvenile and Adult Hippocampus. [PDF]

open access: yes, 2015
Cellular edema (cell swelling) is a principal component of numerous brain disorders including ischemia, cortical spreading depression, hyponatremia, and epilepsy.
Binder, Devin K   +5 more
core   +3 more sources

Recent Advances in Decoupling Strategies for Soft Sensors

open access: yesAdvanced Science, EarlyView.
This review provides an overview of recent advances in decoupling strategies for soft sensors. It summarizes single‐modal sensors that are insensitive to stretching, bending, crosstalk, and other environmental interferences, and highlights emerging multimodal decoupling methods enabled by spatiotemporal information and machine learning.
Yangbo Yuan   +4 more
wiley   +1 more source

Disinhibition of hippocampal CA3 neurons induced by suppression of an adenosine A1 receptor-mediated inhibitory tonus: Pre- and postsynaptic components [PDF]

open access: yes, 1993
Intracellular recordings were performed on hippocampal CA3 neuronsin vitro to investigate the inhibitory tonus generated by endogenously produced adenosine in this brain region.
Alzheimer   +60 more
core   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

open access: yesAdvanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li   +9 more
wiley   +1 more source

From Individual to Population: Circuit Organization of Pyramidal Tract and Intratelencephalic Neurons in Mouse Sensorimotor Cortex

open access: yesResearch
The sensorimotor cortex participates in diverse functions with different reciprocally connected subregions and projection-defined pyramidal neuron types therein, while the fundamental organizational logic of its circuit elements at the single-cell level ...
Mei Yao   +9 more
doaj   +1 more source

Role of microglia disturbances and immune-related marker abnormalities in cortical circuitry dysfunction in schizophrenia

open access: yesNeurobiology of Disease, 2017
Studies of genetics, serum cytokines, and autoimmune illnesses suggest that immune-related abnormalities are involved in the disease process of schizophrenia.
David W. Volk
doaj   +1 more source

Neuromodulatory control of localized dendritic spiking in critical period cortex. [PDF]

open access: yes, 2019
Sensory experience in early postnatal life, during so-called critical periods, restructures neural circuitry to enhance information processing1. Why the cortex is susceptible to sensory instruction in early life and why this susceptibility wanes with age
Ringach, Dario L   +2 more
core  

vEMRec: High‐Resolution Volume Electron Microscopy Reconstruction Based on Structure‐Preserving and High‐Fidelity 3D Alignment

open access: yesAdvanced Science, EarlyView.
vEMRec is a frequency‐adaptive computational framework for three‐dimensional alignment in volume electron microscopy. It integrates feature‐based rigid alignment with Gaussian filter‐guided elastic registration to correct rigid misalignments and nonlinear distortions while preserving structural fidelity.
Zhenbang Zhang   +7 more
wiley   +1 more source

A simulation study on the effects of dendritic morphology on layer V PFC pyramidal cell firing behavior

open access: yesFrontiers in Systems Neuroscience, 2014
The majority of neuronal cells found in the cerebral cortex are pyramidal neurons. Their function has been associated with higher cognitive and emotional functions. Pyramidal neurons have a characteristic structure, consisting of a triangular shaped soma
Maria Psarrou   +3 more
doaj   +1 more source

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