Potent spinal parenchymal AAV9-mediated gene delivery by subpial injection in adult rats and pigs. [PDF]
, 2016 Effective in vivo use of adeno-associated virus (AAV)-based vectors to achieve gene-specific silencing or upregulation in the central nervous system has been limited by the inability to provide more than limited deep parenchymal expression in adult ...
Ahrens, Eric T +14 more
core +3 more sources
Physical and Cognitive Functioning After 3 Years Can Be Predicted Using Information From the Diagnostic Process in Recently Diagnosed Multiple Sclerosis [PDF]
, 2009 Objective\ud To predict functioning after 3 years in patients with recently diagnosed multiple sclerosis (MS).\ud \ud Design\ud Inception cohort with 3 years of follow-up.
Beckerman, Heleen +9 more
core +7 more sources
Correlation of hippocampal theta rhythm with changes in cutaneous temperature [PDF]
A possible role for the hippocampus in alerting an animal to changes in cutaneous temperature was examined. Following local warming or cooling of the ears of unanesthetized, loosely restrained rabbits, theta waves (4-7 Hz EEG waves) were recorded from ...
Horowitz, J. M. +2 more
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Amyotrophic Lateral Sclerosis [PDF]
, 2019 The word amyotrophic is derived from Greek, and means “without nourishment to muscles”, lateral means to the sides and sclerosis means hardened (“What is ALS?,” n.d.).
Georgetson, Anastasia M.
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Experimental Studies on the March of Spasm During Epileptic Convulsion [PDF]
, 1954 March of spasm in epileptic convulsions was first observed by Tackson in 1863, when he said that in certain epileptic convulsions there is a phenomenon, where the convulsion starts from a certain muscle group and gradually spreads to other muscle groups.
Jinnai, Dennosuke +3 more
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Indian Journal of Radiology and Imaging, 2018 Malformations involving the brainstem are very rare and present with a varied spectrum of clinical symptoms due to multiple cranial nerve palsies and pyramidal tract involvement.
Aanchal Bhayana +3 more
doaj +1 more source
Optimized Tractography Mapping and Quantitative Evaluation of Pyramidal Tracts for Surgical Resection of Insular Gliomas: a Correlative Study with Diffusion Tensor Imaging-Derived Metrics and Patient Motor Strength. [PDF]
J Digit Imaging, 2022 Li Y, Hou Y, Li Q, Tang J, Lu J.
europepmc +1 more source
Modeling transcranial magnetic stimulation from the induced electric fields to the membrane potentials along tractography-based white matter fiber tracts [PDF]
, 2016 Objective. Transcranial magnetic stimulation (TMS) is a promising non-invasive tool for modulating the brain activity. Despite the widespread therapeutic and diagnostic use of TMS in neurology and psychiatry, its observed response remains hard to predict,
Crevecoeur, Guillaume +2 more
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Thermal constraints on in vivo optogenetic manipulations. [PDF]
, 2019 A key assumption of optogenetics is that light only affects opsin-expressing neurons. However, illumination invariably heats tissue, and many physiological processes are temperature-sensitive.
Kreitzer, Anatol C +2 more
core
Contextual modulation of primary visual cortex by auditory signals [PDF]
, 2017 Early visual cortex receives non-feedforward input from lateral and top-down connections (Muckli & Petro 2013 Curr. Opin. Neurobiol. 23, 195–201. (doi:10.1016/j.conb.2013.01.020)), including long-range projections from auditory areas.
Muckli, L., Paton, A.T., Petro, L.S.
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