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Visualizing Wallerian degeneration in the corticospinal tract after sensorimotor cortex ischemia in mice [PDF]

open access: yesNeural Regeneration Research, 2023
Stroke can cause Wallerian degeneration in regions outside of the brain, particularly in the corticospinal tract. To investigate the fate of major glial cells and axons within affected areas of the corticospinal tract following stroke, we induced ...
Jiao Mu   +8 more
doaj   +3 more sources

Investigating the Association of Wallerian Degeneration and Diaschisis After Ischemic Stroke With BOLD Cerebrovascular Reactivity [PDF]

open access: yesFrontiers in Physiology, 2021
IntroductionWallerian degeneration and diaschisis are considered separate remote entities following ischemic stroke. They may, however, share common neurophysiological denominators, since they are both related to disruption of fiber tracts and brain ...
C. H. B. van Niftrik   +16 more
doaj   +3 more sources

Role of microtubule dynamics in Wallerian degeneration and nerve regeneration after peripheral nerve injury [PDF]

open access: yesNeural Regeneration Research, 2022
Wallerian degeneration, the progressive disintegration of distal axons and myelin that occurs after peripheral nerve injury, is essential for creating a permissive microenvironment for nerve regeneration, and involves cytoskeletal reconstruction. However,
Jingmin Liu   +16 more
doaj   +3 more sources

Macrophage-specific RhoA knockout delays Wallerian degeneration after peripheral nerve injury in mice [PDF]

open access: yesJournal of Neuroinflammation, 2021
Background Plenty of macrophages are recruited to the injured nerve to play key roles in the immunoreaction and engulf the debris of degenerated axons and myelin during Wallerian degeneration, thus creating a conducive microenvironment for nerve ...
Jiawei Xu   +11 more
doaj   +3 more sources

Ascorbic acid accelerates Wallerian degeneration after peripheral nerve injury [PDF]

open access: yesNeural Regeneration Research, 2021
Wallerian degeneration occurs after peripheral nerve injury and provides a beneficial microenvironment for nerve regeneration. Our previous study demonstrated that ascorbic acid promotes peripheral nerve regeneration, possibly through promoting Schwann ...
Lixia Li   +7 more
doaj   +3 more sources

Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration

open access: yesNeurobiology of Disease, 2020
Wallerian degeneration of physically injured axons involves a well-defined molecular pathway linking loss of axonal survival factor NMNAT2 to activation of pro-degenerative protein SARM1.
Andrea Loreto   +2 more
exaly   +4 more sources

Wallerian degeneration: From mechanism to disease to imaging [PDF]

open access: yesHeliyon
Wallerian degeneration (WD) was first discovered by Augustus Waller in 1850 in a transection of the glossopharyngeal and hypoglossal nerves in frogs. Initial studies suggested that the formation mechanism of WD is related to the nutrition of neuronal ...
Ruiqi Tian   +4 more
doaj   +3 more sources

MRI of Wallerian Degeneration in the Brainstem: A Pictorial Essay [PDF]

open access: yesJournal of the Belgian Society of Radiology, 2021
Wallerian degeneration of the cerebral peduncle is a common MRI finding after cerebral injury. The degree of peduncular atrophy reflects the extent of damage in the corticospinal tract.
Nico Hustings, Marc Lemmerling
doaj   +2 more sources

Wallerian degeneration of the ipsilateral middle cerebellar peduncle after lower pontine paramedian infarct diagnosed by magnetic resonance imaging [PDF]

open access: yesRadiology Case Reports, 2023
We reported a case of Wallerian degeneration of the unilateral middle cerebellar peduncle (MCP) that developed after ipsilateral paramedian lower pontine infarction. The patient was a 70-year-old woman with right hemiparesis and dysarthria.
Akira Uchino, MD, PhD   +1 more
doaj   +2 more sources

Phagocytosis and self-destruction break down dendrites of Drosophila sensory neurons at distinct steps of Wallerian degeneration [PDF]

open access: yesProc Natl Acad Sci U S A, 2022
Significance Mutations in the nicotinamide adenine dinucleotide (NAD+) biosynthesis pathway are associated with progressive neurodegeneration; neuronal injury causes rapid breakdown of damaged axons and dendrites.
Hui Ji   +4 more
semanticscholar   +2 more sources

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