Results 11 to 20 of about 346,229 (227)

Targeting Wallerian degeneration in glaucoma [PDF]

Neural Regeneration Research
Melissa Jöe, Pete A. Williams
doaj   +4 more sources

The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (Wld^S) nerves [PDF]

BMC Neuroscience, 2005
Background The progressive nature of Wallerian degeneration has long been controversial. Conflicting reports that distal stumps of injured axons degenerate anterogradely, retrogradely, or simultaneously are based on statistical observations at ...
Grumme Daniela S, Wagner Diana, Adalbert Robert, Beirowski Bogdan, Addicks Klaus, Ribchester Richard R, Coleman Michael P   +6 more
doaj   +3 more sources

Baculoviral inhibitor of apoptosis protein repeat-containing protein 3 delays early Wallerian degeneration after sciatic nerve injury [PDF]

Neural Regeneration Research, 2022
Wallerian degeneration is a complex biological process that occurs after nerve injury, and involves nerve degeneration and regeneration. Schwann cells play a crucial role in the cellular and molecular events of Wallerian degeneration of the peripheral ...
Min Cai, Jian Shao, Bryant Yung, Yi Wang, Nan-Nan Gao, Xi Xu, Huan-Huan Zhang, Yu-Mei Feng, Deng-Bing Yao   +8 more
doaj   +2 more sources

Differential gene and protein expression between rat tibial nerve and common peroneal nerve during Wallerian degeneration

Neural Regeneration Research, 2019
Wallerian degeneration and nerve regeneration after injury are complex processes involving many genes, proteins and cytokines. After different peripheral nerve injuries the regeneration rate can differ.
Yao-Fa Lin, Zheng Xie, Jun Zhou, Gang Yin, Hao-Dong Lin   +4 more
doaj   +2 more sources

Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury

Journal of Neuroinflammation, 2019
Background Recovery of function from traumatic nerve injury depends on the ability of severed axons to grow/regenerate back to their target tissues. This is achieved by successfully crossing the lesion site where physical impact severed axons, determined
Gerard Elberg, Sigal Liraz-Zaltsman, Fanny Reichert, Takashi Matozaki, Michael Tal, Shlomo Rotshenker   +5 more
doaj   +2 more sources

Imaging resident and recruited macrophage contribution to Wallerian degeneration [PDF]

J Exp Med, 2020
This work describes the spatiotemporal orchestration of recently recruited monocyte-derived and resident macrophages during Wallerian degeneration induced by chronic constriction injury of the sciatic nerve and unveils distinct contribution of these two ...
A. Boissonnas, Floriane Louboutin, Marie Laviron, Pierre-Louis Loyher, É. Reboussin, S. Barthélémy, A. Réaux-le Goazigo, C. Lobsiger, B. Combadière, S. Mélik Parsadaniantz, C. Combadière   +10 more
semanticscholar   +2 more sources

Wallerian degeneration as a therapeutic target in traumatic brain injury [PDF]

Curr Opin Neurol, 2019
Purpose of review Diffuse or traumatic axonal injury is one of the principal pathologies encountered in traumatic brain injury (TBI) and the resulting axonal loss, disconnection, and brain atrophy contribute significantly to clinical morbidity and ...
V. Koliatsos, AS Alexandris
semanticscholar   +2 more sources

Critical signaling pathways during Wallerian degeneration of peripheral nerve

Neural Regeneration Research, 2017
Wallerian degeneration is a critical biological process that occurs in distal nerve stumps after nerve injury. To systematically investigate molecular changes underlying Wallerian degeneration, we used a rat sciatic nerve transection model to examine ...
Qiong Cheng, Ya-xian Wang, Jun Yu, Sheng Yi   +3 more
doaj   +2 more sources

Neutrophils delay repair process in Wallerian degeneration by releasing NETs outside the parenchyma [PDF]

Life Science Alliance, 2022
Neutrophils accumulate at the epineurium in Wallerian degeneration (WD) and inhibit macrophage infiltration from the epineurium into the parenchyma by releasing neutrophil extracellular traps, resulting in the delay of repair processes in WD.
Yasuhiro Yamamoto, Ken Kadoya, Mohamad Alaa Terkawi, Takeshi Endo, Kohtarou Konno, Masahiko Watanabe, Satoshi Ichihara, Akira Hara, Kazuo Kaneko, Norimasa Iwasaki, Muneaki Ishijima   +10 more
doaj   +2 more sources

Wallerian degeneration of the middle cerebellar peduncles secondary to pontine infarction, case report, and review of literature [PDF]

Radiology Case Reports
Wallerian degeneration (WD) is a process of axonal degradation that occurs downstream from a primary injury site and is often seen after strokes affecting the brainstem. This case report documents WD of the bilateral middle cerebellar peduncles (MCPs) in
Zaina Brinji, Dania G Felemban, Basem Bahakeem, Mohammed H Almatrafi   +3 more
doaj   +2 more sources