Results 41 to 50 of about 12,188 (198)

Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF [PDF]

, 2002
Injury to peripheral nerves results in the infiltration of immune cells, which remove axonal- and myelin-derived material. Schwann cells could play a key role in this process by regulating macrophage infiltration.
George K. Tofaris, Kristjan R. Jessen, Rhona Mirsky, Jessen, KR, Patterson, PH, Tofaris, GK, Mirsky, R, Paul H. Patterson   +7 more
core   +1 more source

Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury

Journal of Neuroinflammation, 2019
Background Recovery of function from traumatic nerve injury depends on the ability of severed axons to grow/regenerate back to their target tissues. This is achieved by successfully crossing the lesion site where physical impact severed axons, determined
Gerard Elberg, Sigal Liraz-Zaltsman, Fanny Reichert, Takashi Matozaki, Michael Tal, Shlomo Rotshenker   +5 more
doaj   +1 more source

The Gene for Slow Wallerian Degeneration (Wlds) Is Also Protective against Vincristine Neuropathy

Neurobiology of Disease, 2001
Neurological diseases are frequently associated with axonal degeneration, which leads to dysfunction though separation of neurons from their targets. The mechanisms of axonal degeneration are largely unknown and in many cases are independent of those ...
Min-Sheng Wang, Yue Wu, Deborah G. Culver, Jonathan D. Glass   +3 more
doaj   +1 more source

Different protein expression patterns in rat spinal nerves during Wallerian degeneration assessed using isobaric tags for relative and absolute quantitation proteomics profiling

Neural Regeneration Research, 2020
Sensory and motor nerve fibers of peripheral nerves have different anatomies and regeneration functions after injury. To gain a clear understanding of the biological processes behind these differences, we used a labeling technique termed isobaric tags ...
Shuai Wei, Xue-Zhen Liang, Qian Hu, Wei-Shan Wang, Wen-Jing Xu, Xiao-Qing Cheng, Jiang Peng, Quan-Yi Guo, Shu-Yun Liu, Wen Jiang, Xiao Ding, Gong-Hai Han, Ping Liu, Chen-Hui Shi, Yu Wang   +14 more
doaj   +1 more source

Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis [PDF]

, 2017
Background: Axonal damage and loss substantially contribute to the incremental accumulation of clinical disability in progressive multiple sclerosis. Here, we assessed the amount of Wallerian degeneration in brain tissue of multiple sclerosis patients in
Dallenga, Tobias, Brigitte Maruschak, Brueck, Wolfgang, Singh, Shailender, Siebert, Heike, Wolfgang Brück, Winkler, Anne, Stadelmann, Christine, Anne Winkler, Shailender Singh, Christine Stadelmann, Tobias Dallenga, Shanu Roemer, Heike Siebert, Roemer, Shanu, Maruschak, Brigitte   +15 more
core   +1 more source

Hot Cross Bun Sign Following Bilateral Pontine Infarction: A Case Report [PDF]

Journal of Movement Disorders, 2013
The hot cross bun sign is characterized by cruciform T2 signal hyperintensity in the pons and has been reported to be a specific but not pathognomic for multiple system atrophy.
Sook Young Roh, Hyun-soon Jang, Yoon Hee Kim   +2 more
doaj   +1 more source

Ingenuity pathway analysis of gene expression profiles in distal nerve stump following nerve injury: insights into Wallerian degeneration

Frontiers in Cellular Neuroscience, 2016
Nerve injury is a common and difficult clinical problem worldwide with a high disability rate. Different from the central nervous system, the peripheral nervous system is able to regenerate after injury.
Jun Yu, Xiaosong Gu, Sheng Yi
doaj   +1 more source

Dynamic and Objective Quantification of Facial Nerve Palsy Using Smartphone‐Based 3D Facial Geometry

The Laryngoscope, EarlyView.
This prospective study evaluated smartphone‐captured high‐resolution 3D facial geometry in 99 patients with unilateral facial nerve palsy across 207 visits and 12 healthy volunteers. Dynamic motion features combined with machine learning accurately estimated signed continuous House–Brackmann severity and identified clinically significant palsy ...
Koki Hasebe, Tsuyoshi Kojima, Shintaro Fujimura, Kuniaki Takata, Shuya Otsuki, Ryohei Yuki, Yusuke Okanoue, Harukazu Hiraumi, Ryusuke Hori, Koichi Omori   +9 more
wiley   +1 more source

Tracing of Neuronal Connections in the Human Brain by Magnetic Resonance Imaging in vivo [PDF]

, 1990
Axon degeneration after disruption of fibre tracts in the mammalian nervous system is accompanied by myelin breakdown which leads to changes in its magnetic resonance properties.
Danek, Adrian, Bauer, W. M., Fries, Wolfgang   +2 more
core  

Temperature Modulation Reveals Three Distinct Stages of Wallerian Degeneration [PDF]

, 1999
After peripheral nerve transection, axons distal to the cut site rapidly degenerate, a process termed Wallerian degeneration. In wild-type mice the compound action potential (CAP) disappears by 3 d.
John W. Griffin, Jack W. Tsao, Edwin B. George   +2 more
core   +1 more source