Results 41 to 50 of about 176,284 (162)
Brain and Behavior, 2021 Background Transection‐induced axonal retrograde degeneration, in contrast to Wallerian degeneration, has not been widely recognized in clinical practice.
Yusuke Osaki +3 more
doaj +1 more source
Interdisciplinary Medicine, EarlyView.Schematic depicting a gut‐brain pathway that exacerbates CST injury after ICH. Gut Microbiota Dysbiosis‐Mediated Gut NLRP3 Inflammasome Activation Exacerbates Corticospinal Tract Injury After Intracerebral Hemorrhage. Abstract Intracerebral hemorrhage (ICH) causes severe neurological deficits largely attributable to corticospinal tract (CST) injury ...
Meiqin Zeng +11 more
wiley +1 more source
Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons.
PLoS Biology, 2010 The molecular triggers for axon degeneration remain unknown. We identify endogenous Nmnat2 as a labile axon survival factor whose constant replenishment by anterograde axonal transport is a limiting factor for axon survival.
Jonathan Gilley, Michael P Coleman
doaj +1 more source
Psychiatry and Clinical Psychopharmacology, 2021 The bilateral and symmetrical Wallerian degeneration (WD) of the middle cerebella peduncles (MCPs) is rarely reported in pontine hemorrhage. We described a patient with WD of bilateral MCPs secondary to a strip of unilateral and transversal pontine ...
Dawei Chen, Jin Shi
doaj +1 more source
Dynamic and Objective Quantification of Facial Nerve Palsy Using Smartphone‐Based 3D Facial Geometry
The Laryngoscope, EarlyView.This prospective study evaluated smartphone‐captured high‐resolution 3D facial geometry in 99 patients with unilateral facial nerve palsy across 207 visits and 12 healthy volunteers. Dynamic motion features combined with machine learning accurately estimated signed continuous House–Brackmann severity and identified clinically significant palsy ...
Koki Hasebe +9 more
wiley +1 more source
Novel Injectable Supports Long‐Term Recurrent Laryngeal Nerve and Partial Peripheral Nerve Repair
The Laryngoscope, EarlyView.Following recurrent laryngeal nerve transection in C57BL/6 mice, intramuscular Agrin, neuregulin‐1, and acetylcholine treatment of the thyroarytenoid muscle supported functional reinnervation and preservation of neuromuscular structure at 84 days.
Aditya Bhatt +10 more
wiley +1 more source
Impact of Age and Nerve Impairment Interaction on Bell's Palsy Prognosis
The Laryngoscope, EarlyView.This study investigated the prognostic impact of the interaction between aging and nerve impairment severity in 181 patients with Bell's palsy. Although age alone was not an independent predictor, the interaction between older age (≥ 65 years) and a Nerve Excitability Test threshold difference (≥ 3.5 mA) significantly increased the risk of incomplete ...
Hiroyuki Yamada +7 more
wiley +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith +5 more
wiley +1 more source
Targeted Muscle Reinnervation for Intuitive Prosthetic Control
Muscle &Nerve, EarlyView.ABSTRACT The convergence of medical and technological advances has led to a substantial expansion of therapeutic approaches for patients with limb amputations. Targeted muscle reinnervation (TMR) is one of the strategies to improve control of bionic arms and has been applied for more than two decades. Through surgical rewiring of the nerves responsible
Nitay Maile +5 more
wiley +1 more source