Results 61 to 70 of about 176,284 (162)

SUN11602 Accelerates Early Peripheral Nerve Regeneration in an Experimental Median Nerve Transection Model

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Peripheral nerve injury (PNI) is one of the common life‐altering disabilities resulting in various degrees of impairment in movement and sensation alongside apraxia and long‐lasting pain. The gold standard for restoring the transected nerves is bridging the distal and proximal ends of disrupted autologous nerve using neurosurgical sutures ...
Giovanna Casili   +8 more
wiley   +1 more source

Longitudinal Single‐Axon‐Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant

open access: yesAdvanced Science, Volume 13, Issue 53, 24 September 2026.
A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky   +15 more
wiley   +1 more source

Decalcified and Decellularized Bone Conduits for Peripheral Nerve Regeneration: A Comparative In Vivo Study Using Rat Femur and Chicken Ulna Conduits

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Purpose: Peripheral nerve injuries (PNIs) pose a major clinical challenge, especially when nerve gaps exceed 5 mm and spontaneous regeneration is inadequate. This study aimed to evaluate the regenerative potential of novel bone‐derived nerve guidance conduits (NGCs) fabricated from rat femoral diaphysis and chicken ulna as alternatives to ...
Zahra Sepehri   +3 more
wiley   +1 more source

Case Report Bilateral Wallerian Degeneration of the Pontocerebellar Tracts

open access: yes, 2020
Wallerian degeneration is the process of progressive demyelination and disintegration of the distal axonal segment following the transection of the axon or damage to the neuron.
Aynur Turan   +4 more
core  

The role of TNF-alpha during Wallerian degeneration

open access: yes, 2000
The role of TNF-alpha in the course of Wallerian degeneration of the sciatic nerve was studied in control and TNF-alpha deficient mice. In control animals, the characteristic phenomena of Wallerian degeneration such as axon and myelin degeneration as ...
Michel, Uwe   +5 more
core   +1 more source

Calpains mediate axonal cytoskeleton disintegration during Wallerian degeneration

open access: yesNeurobiology of Disease, 2013
In both the central nervous system (CNS) and peripheral nervous system (PNS), transected axons undergo Wallerian degeneration. Even though Augustus Waller first described this process after transection of axons in 1850, the molecular mechanisms may be ...
Marek Ma   +7 more
doaj   +1 more source

Schwann Cells in Physical Nerve Injury and Tumor Perineural Invasion: A Functional Overview and Comparison

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT The nervous system exhibits remarkable stability, making its repair challenging. Compared to the central nervous system, peripheral nerve injuries demonstrate a greater potential for regeneration. Schwann cells, the unique myelinating glial cells of the peripheral nervous system, possess striking plasticity and support nerve regeneration ...
Yanni Zheng   +7 more
wiley   +1 more source

Wallerian degeneration of pyramidal tract after paramedian pons infarct

open access: yes, 2010
The intention of this study was the prospective analysis of Wallerian degeneration of the pyramidal tract after paramedian pons infarction.Patients with paramedian pons infarct underwent MR imaging including diffusion tensor imaging at admission and got ...
Gräßel, David   +23 more
core   +1 more source

Time‐Continuous Prognostic Mapping of Bell's Palsy Using Yanagihara Scores and Electroneurography

open access: yesThe Laryngoscope, Volume 136, Issue 9, Page 4015-4024, September 2026.
This study developed a novel, time‐continuous prognostic mapping for Bell's palsy by integrating longitudinal Yanagihara scores and electroneurography in patients treated with high‐dose corticosteroids. By employing a Bayesian probabilistic approach, this model enables individualized recovery estimation at any clinical time point, overcoming the ...
Shogo N. Watanabe   +4 more
wiley   +1 more source

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