Results 61 to 70 of about 346,229 (227)
Structural and Functional Imaging of Motor Outcomes in Twins With Perinatal Stroke: A Case Report
Annals of the Child Neurology Society, EarlyView.ABSTRACT Background Perinatal arterial ischemic stroke (AIS) affects 1 in 4000 live births. Dystonia, affecting ~20% of children following AIS, is characterized by involuntary muscle contractions and abnormal movements. Why some develop dystonia post AIS, while others do not, remains unclear.
Prisca Hsu +8 more
wiley +1 more source
Stronger prediction of motor recovery and outcome post-stroke by cortico-spinal tract integrity than functional connectivity [PDF]
, 2018 ObjectivesTo examine longitudinal changes in structural and functional connectivity post-stroke in patients with motor impairment, and define their importance for recovery and outcome at 12 months.MethodsFirst-time stroke patients (N = 31) were studied ...
Corbetta, Maurizio +6 more
core +3 more sources
Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration
Neurobiology of Disease, 2008 Axon loss in the CNS is characteristic of many neurodegenerative diseases but the mechanisms of axon degeneration are poorly understood. In particular, we know little of the inflammatory response triggered by CNS axon degeneration with comparison to that
Karine Palin +4 more
doaj +1 more source
Brain and Behavior, 2021 Background Transection‐induced axonal retrograde degeneration, in contrast to Wallerian degeneration, has not been widely recognized in clinical practice.
Yusuke Osaki +3 more
doaj +1 more source
eNeuro, 2019 Many brain regions go through critical periods of development during which plasticity is enhanced. These critical periods are associated with extensive growth and retraction of thalamocortical and intracortical axons.
Mariska van Lier +8 more
semanticscholar +1 more source
Developmental Dynamics, EarlyView.Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore +7 more
wiley +1 more source
Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons.
PLoS Biology, 2010 The molecular triggers for axon degeneration remain unknown. We identify endogenous Nmnat2 as a labile axon survival factor whose constant replenishment by anterograde axonal transport is a limiting factor for axon survival.
Jonathan Gilley, Michael P Coleman
doaj +1 more source
Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng +6 more
wiley +1 more source
Longitudinal assessment of white matter pathology in the injured mouse spinal cord through ultra-high field (16.4T) in vivo diffusion tensor imaging [PDF]
, 2013 This study examined the sensitivity of ultra-high field (16.4 T) diffusion tensor imaging (DTI; 70 mu m in-plane resolution, 1 mm slice thickness) to evaluate the spatiotemporal development of severe mid-thoracic contusive spinal cord injury (SCI) in ...
Brennan, Faith H. +3 more
core +1 more source
Death Receptor 6 Promotes Wallerian Degeneration in Peripheral Axons
Current Biology, 2017 Axon degeneration during development is required to sculpt a functional nervous system and is also a hallmark of pathological insult, such as injury [1, 2].
K. Gamage +8 more
semanticscholar +2 more sources