Wallerian Degeneration Surveyed in Poliomyelitis [PDF]
Poliomyelitis is a highly infectious disease rendering varying degrees of respiratory illness, gastroenteritis, malaise and potentially severe forms of paralysis. Infection is generated by a virus belonging in the Picornaviridae family.
Kelliher, Kevin R. +4 more
core
Guillain-Barré syndrome: a century of progress [PDF]
In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts — novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS).
A Campbell +91 more
core +1 more source
Therapeutic potential of mesenchymal stem cells in peripheral nerve injuries in horses
Summary Peripheral nerve injuries (PNI) in horses represent a significant clinical challenge, frequently associated with functional deficits and reduced athletic performance. Conventional therapeutic approaches, primarily based on anti‐inflammatory treatments and rehabilitation, offer limited efficacy, driving the search for innovative alternatives. In
L. V. de Oliveira Ferreira +1 more
wiley +1 more source
Severity of Spinal Cord Injury Influences Diffusion Tensor Imaging of the Brain [PDF]
Background: The purpose of this study was to determine whether DTI changes in the brain induced by a thoracic spinal cord injury are sensitive to varying severity of spinal contusion in rats. Methods: A control, mild, moderate, or severe contusion injury
Budde, Matthew D. +4 more
core +1 more source
Perinatal Post‐Anoxic Spinal Cord Injury: A Barrier to Pallidal Neuromodulation? About 2 Cases
Movement Disorders Clinical Practice, EarlyView.
Marylou Grasso +4 more
wiley +1 more source
Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz +20 more
wiley +1 more source
Genomic Analysis of Drosophila Neuronal Remodeling: A Role for the RNA-Binding Protein Boule as a Negative Regulator of Axon Pruning [PDF]
Drosophila mushroom body (MB) {gamma} neurons undergo axon pruning during metamorphosis through a process of localized degeneration of specific axon branches.
Hoopfer, Eric D. +3 more
core +1 more source
Peptide‐Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries
Peptide‐incorporated biomaterials provide precise, tunable biological cues that mimic functional protein domains to regulate behaviors of neurons, Schwann cells, immune cells, and endothelial cells, thereby enhancing axon elongation, Schwann cell support, inflammatory microenvironment modulation, and vascularization, offering a promising alternative to
Zhiwei Zhao +5 more
wiley +1 more source
Early myelin breakdown following sural nerve crush: a freeze-fracture study
In this study we describe the early changes of the myelin sheath following surgical nerve crush. We used the freeze-fracture technique to better evaluate myelin alterations during an early stage of Wallerian degeneration.
A.M.B. Martinez, S. Canavarro
doaj +1 more source
Signaling mechanisms regulating Wallerian degeneration [PDF]
Wallerian degeneration (WD) occurs after an axon is cut or crushed and entails the disintegration and clearance of the severed axon distal to the injury site. WD was initially thought to result from the passive wasting away of the distal axonal fragment, presumably because it lacked a nutrient supply from the cell body.
openaire +3 more sources

