Results 71 to 80 of about 12,188 (198)

Extent of pontine pyramidal tract Wallerian degeneration and outcome after supratentorial hemorrhagic stroke. [PDF]

open access: yes, 1994
Pyramidal tract Wallerian degeneration has been detected on magnetic resonance imaging (MRI) as T2-weighted high-intensity areas. We analyzed the relation between the extent of brain stem Wallerian degeneration and activities of daily living (ADL) after ...
Y Watanabe   +4 more
core   +1 more source

Bilateral Wallerian Degeneration of the Middle Cerebellar Peduncle and Unilateral Hypertrophic Olivary Degeneration Secondary to Pontine Hemorrhage: A Case Report

open access: yes대한영상의학회지, 2018
The two distinct types of axonal degeneration that occur after neuronal injury include Wallerian degeneration (WD) and transneuronal degeneration. The most commonly recognizable cause of secondary degeneration is cerebral infarction, but may also include
Jae Hong Yoon   +4 more
doaj   +1 more source

Molecular Mediators Associated With Myelination, Demyelination, and Remyelination in the Peripheral Nervous System

open access: yesJournal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT The peripheral nervous system (PNS) is responsible for innervating all regions of the body outside of the central nervous system (CNS), the latter consisting of the brain, spinal cord, and optic nerves. While myelin is an essential component for the efficient functioning of both CNS and peripheral nerve cells, it is particularly important for ...
Kathleen Margaret Hagen   +1 more
wiley   +1 more source

A DLK And JNK Dependent Axon Self-Destruction Program Promotes Wallerian Degeneration [PDF]

open access: yes, 2011
Axon loss is a debilitating consequence of a wide range of neurological conditions. As axons degenerate, they go through a stereotyped sequence of morphological changes termed Wallerian degeneration.
Miller, Bradley
core   +2 more sources

Wallerian Degeneration Is Executed by an NMN-SARM1-Dependent Late Ca2+ Influx but Only Modestly Influenced by Mitochondria

open access: yesCell Reports, 2015
Axon injury leads to rapid depletion of NAD-biosynthetic enzyme NMNAT2 and high levels of its substrate, NMN. We proposed a key role for NMN in Wallerian degeneration but downstream events and their relationship to other mediators remain unclear.
Andrea Loreto   +3 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1686-1696, August 2026.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Intra-axonal calcium changes after axotomy in wild-type and slow Wallerian degeneration axons [PDF]

open access: yes, 2012
Calcium accumulation induces the breakdown of cytoskeleton and axonal fragmentation in the late stages of Wallerian degeneration. In the early stages there is no evidence for any long-lasting, extensive increase in intra-axonal calcium but there does ...
Conforti, L.   +13 more
core   +1 more source

Wallerian degeneration of the corticospinal tracts [PDF]

open access: yesNeurology, 2004
A 35-year-old woman experienced acute onset of neck pain with dysarthria and left-sided weakness. Neurologic examination revealed a right-sided Horner’s syndrome, left facial palsy, and left hemiparesis. The diagnostic evaluation disclosed a spontaneous cervicocephalic dissection of the right internal carotid artery with infarction of the anterior ...
openaire   +2 more sources

hUC‐MSCs via β‐NGF Alleviate Cognitive Impairment After Tibial Fracture Surgery by Regulating the STMN2/NMNAT2‐SARM1‐NF‐κB Signaling Pathway

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
This study found that human umbilical cord mesenchymal stem cells secrete β‐NGF, which binds to the TrkA receptor on neurons, upregulates the protein levels of STMN2 and NMNAT2 in mice with perioperative neurocognitive disorders, and thereby downregulates the protein levels of SARM1 and p‐NF‐κB.
Kai Wang   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy