Results 51 to 60 of about 12,188 (198)
Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration
Neurobiology of Disease, 2008 Axon loss in the CNS is characteristic of many neurodegenerative diseases but the mechanisms of axon degeneration are poorly understood. In particular, we know little of the inflammatory response triggered by CNS axon degeneration with comparison to that
Karine Palin +4 more
doaj +1 more source
Brain and Behavior, 2021 Background Transection‐induced axonal retrograde degeneration, in contrast to Wallerian degeneration, has not been widely recognized in clinical practice.
Yusuke Osaki +3 more
doaj +1 more source
Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons.
PLoS Biology, 2010 The molecular triggers for axon degeneration remain unknown. We identify endogenous Nmnat2 as a labile axon survival factor whose constant replenishment by anterograde axonal transport is a limiting factor for axon survival.
Jonathan Gilley, Michael P Coleman
doaj +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith +5 more
wiley +1 more source
A gene affecting Wallerian nerve degeneration maps distally on mouse chromosome 4 [PDF]
, 1993 When a nerve axon is cut or crushed, the nerve fibers in the distal part of the axon, separated from the cell body, undergo a form of spontaneous degeneration, known as Wallerian degeneration.
Atherton, D.J. +4 more
core +1 more source
Psychiatry and Clinical Psychopharmacology, 2021 The bilateral and symmetrical Wallerian degeneration (WD) of the middle cerebella peduncles (MCPs) is rarely reported in pontine hemorrhage. We described a patient with WD of bilateral MCPs secondary to a strip of unilateral and transversal pontine ...
Dawei Chen, Jin Shi
doaj +1 more source
Tempol, a Superoxide Dismutase Mimetic, Inhibits Wallerian Degeneration Following Spinal Cord Injury by Preventing Glutathione Depletion and Aldose Reductase Activation. [PDF]
J NeurotraumaSpinal cord contusion injury results in Wallerian degeneration of spinal cord axonal tracts, which are necessary for locomotor function. Axonal swelling and loss of axonal density at the contusion site, characteristic of Wallerian degeneration, commence ...
Zeman RJ +4 more
europepmc +2 more sources
Targeted Muscle Reinnervation for Intuitive Prosthetic Control
Muscle &Nerve, EarlyView.ABSTRACT The convergence of medical and technological advances has led to a substantial expansion of therapeutic approaches for patients with limb amputations. Targeted muscle reinnervation (TMR) is one of the strategies to improve control of bionic arms and has been applied for more than two decades. Through surgical rewiring of the nerves responsible
Nitay Maile +5 more
wiley +1 more source