Results 101 to 110 of about 12,077 (200)

Aldose reductase deficiency improves wallerian degeneration and nerve regeneration in diabetic thy1-YFP mice

, 2010
This study examined the role of aldose reductase (AR) in diabetes-associated impaired nerve regeneration using thy1-YFP (YFP) mice. Sciatic nerves of nondiabetic and streptozotocin-induced diabetic AR +/+YFP and AR-/-YFP mice were transected after 4 ...
Chung, SK, Chung, SS, Chen, YS
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Extent of pontine pyramidal tract Wallerian degeneration and outcome after supratentorial hemorrhagic stroke.

, 1994
Pyramidal tract Wallerian degeneration has been detected on magnetic resonance imaging (MRI) as T2-weighted high-intensity areas. We analyzed the relation between the extent of brain stem Wallerian degeneration and activities of daily living (ADL) after ...
Y Watanabe, K Fukui, K Sugita, I Iguchi, A Kito   +4 more
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A DLK And JNK Dependent Axon Self-Destruction Program Promotes Wallerian Degeneration

, 2011
Axon loss is a debilitating consequence of a wide range of neurological conditions. As axons degenerate, they go through a stereotyped sequence of morphological changes termed Wallerian degeneration.
Miller, Bradley
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Acute Wallerian degeneration of middle cerebellar peduncles due to basilar artery thrombosis

Indian Journal of Radiology and Imaging, 2013
Wallerian degeneration (WD) is the process of demyelination and disintegration of the distal axonal segment following the interruption of the axonal integrity or damage to the neuron.
Foram Gala, Anton Becker, Markus Pfeiffer, Spyros Kollias   +3 more
doaj   +1 more source

Intra-axonal calcium changes after axotomy in wild-type and slow Wallerian degeneration axons

, 2012
Calcium accumulation induces the breakdown of cytoskeleton and axonal fragmentation in the late stages of Wallerian degeneration. In the early stages there is no evidence for any long-lasting, extensive increase in intra-axonal calcium but there does ...
Conforti, L., Siklos, L., Bootman, Martin, Siklós, L, Adalbert, R., Coleman, M. P., Walker, S.A., Coleman, M.P., Walker, S. A., Roderick, H. L., Morreale, G., Bootman, M.D., Paizs, M., Roderick, H. Llewelyn   +13 more
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ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury [PDF]

, 2006
Neuregulin/erbB signaling is critically required for survival and proliferation of Schwann cells as well as for establishing correct myelin thickness of peripheral nerves during development.
Atanasoski, Suzana, Birchmeier, C., Garratt, Alistair N., Birchmeier, Carmen, Suter, U., Sirkowski, E., Scherer, Steven S., Atanasoski, S., Suter, Ueli, Scherer, S.S., Sirkowski, Erich, Garratt, A.N., S. Atanasoski, Leone, Dino, Leone, D.   +14 more
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The involvement of Phospholipase, A2 in Wallerian degeneration /

, 1999
Phospholipase A2 (PLA2) enzymes target membrane phospholipids to liberate free fatty acids, such as arachidonic acid, a precursor of inflammatory mediators, as well as lysophospholipids which disrupt membrane structure.
De, Susna R.
core  

Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration

, 2019
Injured axons undergo a controlled, self-destruction process, known as Wallerian degeneration. However, the underlying mechanism remains elusive.
Wang, Xuejie, Zhang, Shuang, Fang, Yanshan, Wang, Haiqiong, Wang, Qingyao, Cao, Xu, Wang, Zhao, Li, Ang, Liu, Kai, Zhang, Kai   +9 more
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Wallerian degeneration : a major component of early axonal pathology in multiple sclerosis

, 2010
Axonal loss is a major component of the pathology of multiple sclerosis (MS) and the morphological basis of permanent clinical disability. It occurs in demyelinating plaques but also in the so-called normal-appearing white matter (NAWM).
Mueller, Sven, Metz, Imke, Dallenga, Tobias, Brück, Wolfgang, König, Fatima Barbara, Koenig, Fatima Barbara, Brueck, Wolfgang, Müller, Sven, Stadelmann, Christine, Dziedzic, Tomasz   +9 more
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Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1 and interleukin-1 in Wallerian degeneration

, 2005
International audienceWallerian degeneration in the CNS and PNS consists of degradation and phagocytosis of axons and their myelin sheath distal to the site of injury.
Perrin, Florence,, Perrin, Florence, E., Lacroix, Steve, Avilés-Trigueros, Marcelino, David, Samuel   +4 more
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