Results 61 to 70 of about 13,686 (260)

Speech Biomarkers for Quantifying Effects of Subthalamic Deep Brain Stimulation in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective Dysarthria is one of the most common and disabling side effects of subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson's disease (PD). Stimulation often exacerbates speech dysfunction beyond the effects of PD progression, likely because of current spread to structures surrounding the STN.
Petr Krýže, Mário Sousa, Vojtěch Illner, Adriana Jorge, Matilde Castelli, Ines Debove, Andreia D. Magalhães, Julia Waskönig, Lenard Lachenmayer, Joan Philipp Michelis, Gerd Tinkhauser, Deborah Amstutz, Marie Elise Maradan‐Gachet, Katrin Petermann, Claudio Pollo, Tobias Nef, Paul Krack, Jan Rusz   +17 more
wiley   +1 more source

Neuroanatomical diversity in Teleocichla with new volumetric and histological insights into the encephalon of Teleocichla monogramma Kullander 1988

The Anatomical Record, EarlyView.
Abstract Teleocichla comprises small cichlids that inhabit the rapid streams of Amazonian rivers; however, there has been limited research on their encephalon morphology. This study examined the neuroanatomy of four species, focusing on volumetric measurements of their encephalon subregions, and providing a histological description of the encephalon of
Renan Leão‐Reis, Keila Xavier Magalhães, Thiago Nilton A. Pereira, Janice Muriel‐Cunha, Alberto Akama   +4 more
wiley   +1 more source

Longitudinal Magnetic Resonance Imaging Study Shows Progressive Pyramidal And Callosal Damage In Friedreich's Ataxia.

, 2016
Spinal cord and peripheral nerves are classically known to be damaged in Friedreich's ataxia, but the extent of cerebral involvement in the disease and its progression over time are not yet characterized.
Lopes-Cendes, Iscia, Yassuda, C. L., Rezende, T. J., Lopes-Cendes, I., Cendes, Fernando, Cendes, F., Campos, Brunno M, Campos, B. M., Yassuda, Clarissa L, França, Marcondes C, D'Abreu, A., França, M. C. Jr., D'Abreu, Anelyssa, Rezende, Thiago J R, Silva, Cynthia B, Silva, C. B.   +15 more
core   +1 more source

Central motor conduction in human chronic Chagas' disease

Arquivos de Neuro-Psiquiatria, 1994
The possible involvement of spinal alpha motor neurons, dorsal root ganglia and sensory fibers in human chronic Chagas' disease was previously demonstrated.
M.J. Segura, O.M. Genovese, Elsa Segura, Olga P. Sanz, R.E.P. Sica   +4 more
doaj   +1 more source

Production of 3D printed biomodels of the canine brain for veterinary neuroanatomy teaching

Anatomical Sciences Education, EarlyView.
Abstract Teaching neuroanatomy presents multiple challenges to both students and teachers, as it is a subject with highly dense content that commonly causes the development of aversion by students, a phenomenon referred to as “neurophobia,” which has been documented in human and veterinary medicine students.
João Victor Barbosa Tenório Fireman, Antônio Chaves de Assis Neto   +1 more
wiley   +1 more source

Modern competency‐based teaching of human sexual development

Anatomical Sciences Education, EarlyView.
Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler, Alessandro Bilella, Christian M. Hammer   +2 more
wiley   +1 more source

Fractional anisotropy in white matter tracts of very-low-birth-weight infants

, 2007
Background: Advances in neonatal intensive care have not yet reduced the high incidence of neurodevelopmental disability among very-low-birth-weight (VLBW) infants. As neurological deficits are related to white-matter injury, early detection is important.
Govaert, Paul, Lequin, Maarten, Dudink, Jeroen, Goudoever, Johannes B van, Lequin, MH, Jan Buijs, Buijs, JA, van Pul, C, Pul, C. (Carola) van, Buijs, J. (Jan), Buijs, Jan, Govaert, P. (Paul), Goudoever, J.B. (Hans) van, Conneman, Nikk, Conneman, N. (Nikk), Jeroen Dudink, Dudink, J. (Jeroen), Leguin, M. (Maarten), Buijs, J, Maarten Lequin, Paul Govaert, Pul, C Carola van, Dudink, J, Nikk Conneman, Carola van Pul, van Goudoever, Johannes, Johannes van Goudoever, Goudoever, Johan, van Pul, Carola   +28 more
core   +1 more source

Lower Striatal and Cortical Calretinin Interneuron Density Associated With Altered Social Behavior in Cntnap2 Knockout Mice

Autism Research, EarlyView.
ABSTRACT Variants in the CNTNAP2 gene, encoding the cell adhesion molecule CASPR2, have been identified as genetic risk factors for autism spectrum disorder (ASD). However, the mechanisms through which CNTNAP2 dysfunction alters circuit function remain unknown.
Krisztina Sáfár, Vivien Szendi, Paulina Hoppa, Yutong Wang, Fanni Á. Seres, Szilvia Bartók, Tyler Teadora, Lei Shi, Árpád Dobolyi, Gina Puska, István Adorján   +10 more
wiley   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

G51D α-synuclein mutation causes a novel parkinsonian-pyramidal syndrome.

, 2013
International audienceTo date, 3 rare missense mutations in the SNCA (α-synuclein) gene and the more frequent duplications or triplications of the wild-type gene are known to cause a broad array of clinical and pathological symptoms in familial Parkinson
K. Madiona, Verny, Christophe, R. Melki, Dürr, Alexandra, L. Pieri, Pieri, Laura, M. Anheim, L. Bousset, A. Honoré, Madiona, Karine, Bousset, Luc, N. Rozas, French Parkinson\u27s Disease Genetics Study Group, Lesage, Suzanne, Anheim, Mathieu, S. Lesage, F. Letournel, Brice, Alexis, C. Verny, Honoré, Aurélie, Rozas, Nelly, A. Dürr, A. Brice, Letournel, Franck, Melki, Ronald   +24 more
core   +1 more source